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625 related items for PubMed ID: 30079598

  • 1. The specificity and role of microglia in epileptogenesis in mouse models of tuberous sclerosis complex.
    Zhang B, Zou J, Han L, Beeler B, Friedman JL, Griffin E, Piao YS, Rensing NR, Wong M.
    Epilepsia; 2018 Sep; 59(9):1796-1806. PubMed ID: 30079598
    [Abstract] [Full Text] [Related]

  • 2. Microglial activation during epileptogenesis in a mouse model of tuberous sclerosis complex.
    Zhang B, Zou J, Han L, Rensing N, Wong M.
    Epilepsia; 2016 Aug; 57(8):1317-25. PubMed ID: 27263494
    [Abstract] [Full Text] [Related]

  • 3. Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner.
    Zou J, Zhang B, Gutmann DH, Wong M.
    Epilepsia; 2017 Dec; 58(12):2053-2063. PubMed ID: 29023667
    [Abstract] [Full Text] [Related]

  • 4. Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex.
    Zeng LH, Xu L, Gutmann DH, Wong M.
    Ann Neurol; 2008 Apr; 63(4):444-53. PubMed ID: 18389497
    [Abstract] [Full Text] [Related]

  • 5. Cerebral vascular and blood brain-barrier abnormalities in a mouse model of epilepsy and tuberous sclerosis complex.
    Guo D, Zhang B, Han L, Rensing NR, Wong M.
    Epilepsia; 2024 Feb; 65(2):483-496. PubMed ID: 38049961
    [Abstract] [Full Text] [Related]

  • 6. Intermittent dosing of rapamycin maintains antiepileptogenic effects in a mouse model of tuberous sclerosis complex.
    Rensing N, Han L, Wong M.
    Epilepsia; 2015 Jul; 56(7):1088-97. PubMed ID: 26122303
    [Abstract] [Full Text] [Related]

  • 7. Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex.
    Zeng LH, Rensing NR, Zhang B, Gutmann DH, Gambello MJ, Wong M.
    Hum Mol Genet; 2011 Feb 01; 20(3):445-54. PubMed ID: 21062901
    [Abstract] [Full Text] [Related]

  • 8. A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficits.
    Feliciano DM, Lin TV, Hartman NW, Bartley CM, Kubera C, Hsieh L, Lafourcade C, O'Keefe RA, Bordey A.
    Int J Dev Neurosci; 2013 Nov 01; 31(7):667-78. PubMed ID: 23485365
    [Abstract] [Full Text] [Related]

  • 9. Sirolimus relieves seizures and neuropsychiatric symptoms via changes of microglial polarity in tuberous sclerosis complex model mice.
    Koike-Kumagai M, Fujimoto M, Wataya-Kaneda M.
    Neuropharmacology; 2022 Nov 01; 218():109203. PubMed ID: 35931213
    [Abstract] [Full Text] [Related]

  • 10. Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin.
    Carson RP, Van Nielen DL, Winzenburger PA, Ess KC.
    Neurobiol Dis; 2012 Jan 01; 45(1):369-80. PubMed ID: 21907282
    [Abstract] [Full Text] [Related]

  • 11. Early developmental electroencephalography abnormalities, neonatal seizures, and induced spasms in a mouse model of tuberous sclerosis complex.
    Rensing N, Johnson KJ, Foutz TJ, Friedman JL, Galindo R, Wong M.
    Epilepsia; 2020 May 01; 61(5):879-891. PubMed ID: 32274803
    [Abstract] [Full Text] [Related]

  • 12. Epileptogenesis and reduced inward rectifier potassium current in tuberous sclerosis complex-1-deficient astrocytes.
    Jansen LA, Uhlmann EJ, Crino PB, Gutmann DH, Wong M.
    Epilepsia; 2005 Dec 01; 46(12):1871-80. PubMed ID: 16393152
    [Abstract] [Full Text] [Related]

  • 13. Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice.
    Haji N, Riebe I, Aguilar-Valles A, Artinian J, Laplante I, Lacaille JC.
    Mol Autism; 2020 May 06; 11(1):29. PubMed ID: 32375878
    [Abstract] [Full Text] [Related]

  • 14. Effects of antiepileptic drugs in a new TSC/mTOR-dependent epilepsy mouse model.
    Koene LMC, van Grondelle SE, Proietti Onori M, Wallaard I, Kooijman NHRM, van Oort A, Schreiber J, Elgersma Y.
    Ann Clin Transl Neurol; 2019 Jul 06; 6(7):1273-1291. PubMed ID: 31353861
    [Abstract] [Full Text] [Related]

  • 15. Upregulation of 6-phosphofructo-2-kinase (PFKFB3) by hyperactivated mammalian target of rapamycin complex 1 is critical for tumor growth in tuberous sclerosis complex.
    Wang Y, Tang S, Wu Y, Wan X, Zhou M, Li H, Zha X.
    IUBMB Life; 2020 May 06; 72(5):965-977. PubMed ID: 31958214
    [Abstract] [Full Text] [Related]

  • 16. Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex.
    Zeng LH, Bero AW, Zhang B, Holtzman DM, Wong M.
    Neurobiol Dis; 2010 Mar 06; 37(3):764-71. PubMed ID: 20045054
    [Abstract] [Full Text] [Related]

  • 17. Inflammatory mechanisms contribute to the neurological manifestations of tuberous sclerosis complex.
    Zhang B, Zou J, Rensing NR, Yang M, Wong M.
    Neurobiol Dis; 2015 Aug 06; 80():70-9. PubMed ID: 26003087
    [Abstract] [Full Text] [Related]

  • 18. Novel brain permeant mTORC1/2 inhibitors are as efficacious as rapamycin or everolimus in mouse models of acquired partial epilepsy and tuberous sclerosis complex.
    Theilmann W, Gericke B, Schidlitzki A, Muneeb Anjum SM, Borsdorf S, Harries T, Roberds SL, Aguiar DJ, Brunner D, Leiser SC, Song D, Fabbro D, Hillmann P, Wymann MP, Löscher W.
    Neuropharmacology; 2020 Dec 01; 180():108297. PubMed ID: 32890589
    [Abstract] [Full Text] [Related]

  • 19. The natural history and treatment of epilepsy in a murine model of tuberous sclerosis.
    Erbayat-Altay E, Zeng LH, Xu L, Gutmann DH, Wong M.
    Epilepsia; 2007 Aug 01; 48(8):1470-6. PubMed ID: 17484760
    [Abstract] [Full Text] [Related]

  • 20. TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling.
    Martin P, Wagh V, Reis SA, Erdin S, Beauchamp RL, Shaikh G, Talkowski M, Thiele E, Sheridan SD, Haggarty SJ, Ramesh V.
    Mol Autism; 2020 Aug 01; 11(1):2. PubMed ID: 31921404
    [Abstract] [Full Text] [Related]


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