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265 related items for PubMed ID: 30108215
1. The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis. Zehender A, Huang J, Györfi AH, Matei AE, Trinh-Minh T, Xu X, Li YN, Chen CW, Lin J, Dees C, Beyer C, Gelse K, Zhang ZY, Bergmann C, Ramming A, Birchmeier W, Distler O, Schett G, Distler JHW. Nat Commun; 2018 Aug 14; 9(1):3259. PubMed ID: 30108215 [Abstract] [Full Text] [Related]
2. Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis. Zhang Y, Dees C, Beyer C, Lin NY, Distler A, Zerr P, Palumbo K, Susok L, Kreuter A, Distler O, Schett G, Distler JH. Ann Rheum Dis; 2015 May 14; 74(5):936-43. PubMed ID: 24431397 [Abstract] [Full Text] [Related]
3. MSU crystallization promotes fibroblast proliferation and renal fibrosis in diabetic nephropathy via the ROS/SHP2/TGFβ pathway. Li J, Zhang J, Zhao X, Tian L. Sci Rep; 2024 Aug 31; 14(1):20251. PubMed ID: 39215017 [Abstract] [Full Text] [Related]
4. The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis. Avouac J, Palumbo-Zerr K, Ruzehaji N, Tomcik M, Zerr P, Dees C, Distler A, Beyer C, Schneider H, Distler O, Schett G, Allanore Y, Distler JH. Arthritis Rheumatol; 2014 Nov 31; 66(11):3140-50. PubMed ID: 25155144 [Abstract] [Full Text] [Related]
5. JAK2 and SHP2 reciprocally regulate tyrosine phosphorylation and stability of proapoptotic protein ASK1. Yu L, Min W, He Y, Qin L, Zhang H, Bennett AM, Chen H. J Biol Chem; 2009 May 15; 284(20):13481-13488. PubMed ID: 19287004 [Abstract] [Full Text] [Related]
6. A shift in the IL-6/STAT3 signalling pathway imbalance towards the SHP2 pathway in severe asthma results in reduced proliferation process. Salem IH, Plante S, Gounni AS, Rouabhia M, Chakir J. Cell Signal; 2018 Mar 15; 43():47-54. PubMed ID: 29242170 [Abstract] [Full Text] [Related]
7. Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis. Chakraborty D, Šumová B, Mallano T, Chen CW, Distler A, Bergmann C, Ludolph I, Horch RE, Gelse K, Ramming A, Distler O, Schett G, Šenolt L, Distler JHW. Nat Commun; 2017 Oct 24; 8(1):1130. PubMed ID: 29066712 [Abstract] [Full Text] [Related]
8. The JAK2 pathway is activated in idiopathic pulmonary fibrosis. Milara J, Hernandez G, Ballester B, Morell A, Roger I, Montero P, Escrivá J, Lloris JM, Molina-Molina M, Morcillo E, Cortijo J. Respir Res; 2018 Feb 06; 19(1):24. PubMed ID: 29409529 [Abstract] [Full Text] [Related]
9. TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy. Zehender A, Li YN, Lin NY, Stefanica A, Nüchel J, Chen CW, Hsu HH, Zhu H, Ding X, Huang J, Shen L, Györfi AH, Soare A, Rauber S, Bergmann C, Ramming A, Plomann M, Eckes B, Schett G, Distler JHW. Nat Commun; 2021 Jul 20; 12(1):4404. PubMed ID: 34285225 [Abstract] [Full Text] [Related]
10. Natural flavonoid pectolinarigenin alleviated kidney fibrosis via inhibiting the activation of TGFβ/SMAD3 and JAK2/STAT3 signaling. Li Y, Guo F, Huang R, Ma L, Fu P. Int Immunopharmacol; 2021 Feb 20; 91():107279. PubMed ID: 33340783 [Abstract] [Full Text] [Related]
11. Stimulation of the soluble guanylate cyclase (sGC) inhibits fibrosis by blocking non-canonical TGFβ signalling. Beyer C, Zenzmaier C, Palumbo-Zerr K, Mancuso R, Distler A, Dees C, Zerr P, Huang J, Maier C, Pachowsky ML, Friebe A, Sandner P, Distler O, Schett G, Berger P, Distler JH. Ann Rheum Dis; 2015 Jul 20; 74(7):1408-16. PubMed ID: 24567525 [Abstract] [Full Text] [Related]
12. SHP2 is induced by the HBx-NF-κB pathway and contributes to fibrosis during human early hepatocellular carcinoma development. Kang HJ, Chung DH, Sung CO, Yoo SH, Yu E, Kim N, Lee SH, Song JY, Kim CJ, Choi J. Oncotarget; 2017 Apr 18; 8(16):27263-27276. PubMed ID: 28460481 [Abstract] [Full Text] [Related]
13. PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling. Zhang P, Yang B, Yao YY, Zhong LX, Chen XY, Kong QY, Wu ML, Li C, Li H, Liu J. Gynecol Oncol; 2015 Dec 18; 139(3):529-35. PubMed ID: 26432044 [Abstract] [Full Text] [Related]
14. Decreased expression of caveolin 1 in patients with systemic sclerosis: crucial role in the pathogenesis of tissue fibrosis. Del Galdo F, Sotgia F, de Almeida CJ, Jasmin JF, Musick M, Lisanti MP, Jiménez SA. Arthritis Rheum; 2008 Sep 18; 58(9):2854-65. PubMed ID: 18759267 [Abstract] [Full Text] [Related]
15. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex. Bode JG, Schweigart J, Kehrmann J, Ehlting C, Schaper F, Heinrich PC, Häussinger D. J Immunol; 2003 Jul 01; 171(1):257-66. PubMed ID: 12817006 [Abstract] [Full Text] [Related]
16. 5-HT2 and 5-HT2B antagonists attenuate pro-fibrotic phenotype in human adult dermal fibroblasts by blocking TGF-β1 induced non-canonical signaling pathways including STAT3 : implications for fibrotic diseases like scleroderma. Chaturvedi S, Misra DP, Prasad N, Rastogi K, Singh H, Rai MK, Agarwal V. Int J Rheum Dis; 2018 Dec 01; 21(12):2128-2138. PubMed ID: 30207074 [Abstract] [Full Text] [Related]
17. The tyrosine phosphatase SHP2 increases robustness and information transfer within IL-6-induced JAK/STAT signalling. Fiebelkow J, Guendel A, Guendel B, Mehwald N, Jetka T, Komorowski M, Waldherr S, Schaper F, Dittrich A. Cell Commun Signal; 2021 Sep 16; 19(1):94. PubMed ID: 34530865 [Abstract] [Full Text] [Related]
18. LncRNA MEG8 sponging miR-181a-5p contributes to M1 macrophage polarization by regulating SHP2 expression in Henoch-Schonlein purpura rats. Jiang M, Dai J, Yin M, Jiang C, Ren M, Tian L. Ann Med; 2021 Dec 16; 53(1):1576-1588. PubMed ID: 34477472 [Abstract] [Full Text] [Related]
19. Pro-fibrotic effect of IL-6 via aortic adventitial fibroblasts indicates IL-6 as a treatment target in Takayasu arteritis. Kong X, Ma L, Ji Z, Dong Z, Zhang Z, Hou J, Zhang S, Ma L, Jiang L. Clin Exp Rheumatol; 2018 Dec 16; 36(1):62-72. PubMed ID: 28770707 [Abstract] [Full Text] [Related]
20. Seasonal leptin resistance is associated with impaired signalling via JAK2-STAT3 but not ERK, possibly mediated by reduced hypothalamic GRB2 protein. Tups A, Stöhr S, Helwig M, Barrett P, Krol E, Schachtner J, Mercer JG, Klingenspor M. J Comp Physiol B; 2012 May 16; 182(4):553-67. PubMed ID: 22198805 [Abstract] [Full Text] [Related] Page: [Next] [New Search]