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Journal Abstract Search

491 related items for PubMed ID: 30119174

  • 1. Novel steroid derivatives: synthesis, antileishmanial activity, mechanism of action, and in silico physicochemical and pharmacokinetics studies.
    da Trindade Granato J, Dos Santos JA, Calixto SL, Prado da Silva N, da Silva Martins J, da Silva AD, Coimbra ES.
    Biomed Pharmacother; 2018 Oct; 106():1082-1090. PubMed ID: 30119174
    [Abstract] [Full Text] [Related]

  • 2. Novel organic salts based on quinoline derivatives: The in vitro activity trigger apoptosis inhibiting autophagy in Leishmania spp.
    Calixto SL, Glanzmann N, Xavier Silveira MM, da Trindade Granato J, Gorza Scopel KK, Torres de Aguiar T, DaMatta RA, Macedo GC, da Silva AD, Coimbra ES.
    Chem Biol Interact; 2018 Sep 25; 293():141-151. PubMed ID: 30098941
    [Abstract] [Full Text] [Related]

  • 3. Synthesis, biological activity, and mechanism of action of new 2-pyrimidinyl hydrazone and N-acylhydrazone derivatives, a potent and new classes of antileishmanial agents.
    Coimbra ES, Nora de Souza MV, Terror MS, Pinheiro AC, da Trindade Granato J.
    Eur J Med Chem; 2019 Dec 15; 184():111742. PubMed ID: 31605866
    [Abstract] [Full Text] [Related]

  • 4. Quinoline derivatives: Synthesis, leishmanicidal activity and involvement of mitochondrial oxidative stress as mechanism of action.
    Coimbra ES, Antinarelli LM, Silva NP, Souza IO, Meinel RS, Rocha MN, Soares RP, da Silva AD.
    Chem Biol Interact; 2016 Dec 25; 260():50-57. PubMed ID: 27789199
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  • 5. Novel functionalized 1,2,3-triazole derivatives exhibit antileishmanial activity, increase in total and mitochondrial-ROS and depolarization of mitochondrial membrane potential of Leishmania amazonensis.
    Meinel RS, Almeida ADC, Stroppa PHF, Glanzmann N, Coimbra ES, da Silva AD.
    Chem Biol Interact; 2020 Jan 05; 315():108850. PubMed ID: 31634447
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  • 6. Antileishmanial Thioureas: Synthesis, Biological Activity and in Silico Evaluations of New Promising Derivatives.
    Viana GM, Soares DC, Santana MV, do Amaral LH, Meireles PW, Nunes RP, da Silva LCRP, Aguiar LCS, Rodrigues CR, de Sousa VP, Castro HC, Abreu PA, Sathler PC, Saraiva EM, Cabral LM.
    Chem Pharm Bull (Tokyo); 2017 Jan 05; 65(10):911-919. PubMed ID: 28966275
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, Biological Activity, and Mechanism of Action of 2-Pyrazyl and Pyridylhydrazone Derivatives, New Classes of Antileishmanial Agents.
    Coimbra ES, Antinarelli LMR, de A Crispi M, Nogueira TCM, Pinheiro AC, de Souza MVN.
    ChemMedChem; 2018 Jul 18; 13(14):1387-1394. PubMed ID: 29790287
    [Abstract] [Full Text] [Related]

  • 8. Investigation of the antileishmanial activity and mechanisms of action of acetyl-thiohydantoins.
    Bortoleti BTDS, Gonçalves MD, Tomiotto-Pellissier F, Camargo PG, Assolini JP, Concato VM, Detoni MB, Bidóia DL, Bispo MLF, Lima CHDS, de Macedo FC, Conchon-Costa I, Miranda-Sapla MM, Wowk PF, Pavanelli WR.
    Chem Biol Interact; 2022 Jan 05; 351():109690. PubMed ID: 34637778
    [Abstract] [Full Text] [Related]

  • 9. Grandiflorenic acid promotes death of promastigotes via apoptosis-like mechanism and affects amastigotes by increasing total iron bound capacity.
    Bortoleti BTDS, Gonçalves MD, Tomiotto-Pellissier F, Miranda-Sapla MM, Assolini JP, Carloto ACM, de Carvalho PGC, Cardoso ILA, Simão ANC, Arakawa NS, Costa IN, Conchon-Costa I, Pavanelli WR.
    Phytomedicine; 2018 Jul 15; 46():11-20. PubMed ID: 30097110
    [Abstract] [Full Text] [Related]

  • 10. Antileishmanial Activity, Cytotoxicity and Mechanism of Action of Clioquinol Against Leishmania infantum and Leishmania amazonensis Species.
    Tavares GSV, Mendonça DVC, Lage DP, Granato JDT, Ottoni FM, Ludolf F, Chávez-Fumagalli MA, Duarte MC, Tavares CAP, Alves RJ, Coimbra ES, Coelho EAF.
    Basic Clin Pharmacol Toxicol; 2018 Sep 15; 123(3):236-246. PubMed ID: 29481714
    [Abstract] [Full Text] [Related]

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  • 12. Morinda citrifolia Linn. fruit (Noni) juice induces an increase in NO production and death of Leishmania amazonensis amastigotes in peritoneal macrophages from BALB/c.
    Almeida-Souza F, de Souza Cda S, Taniwaki NN, Silva JJ, de Oliveira RM, Abreu-Silva AL, Calabrese Kda S.
    Nitric Oxide; 2016 Aug 31; 58():51-8. PubMed ID: 27328771
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  • 16. An effective in vitro and in vivo antileishmanial activity and mechanism of action of 8-hydroxyquinoline against Leishmania species causing visceral and tegumentary leishmaniasis.
    Costa Duarte M, dos Reis Lage LM, Lage DP, Mesquita JT, Salles BC, Lavorato SN, Menezes-Souza D, Roatt BM, Alves RJ, Tavares CA, Tempone AG, Coelho EA.
    Vet Parasitol; 2016 Feb 15; 217():81-8. PubMed ID: 26827866
    [Abstract] [Full Text] [Related]

  • 17. Solidagenone acts on promastigotes of L. amazonensis by inducing apoptosis-like processes on intracellular amastigotes by IL-12p70/ROS/NO pathway activation.
    Bortoleti BTDS, Gonçalves MD, Tomiotto-Pellissier F, Contato VM, Silva TF, de Matos RLN, Detoni MB, Rodrigues ACJ, Carloto AC, Lazarin DB, Arakawa NS, Costa IN, Conchon-Costa I, Miranda-Sapla MM, Wowk PF, Pavanelli WR.
    Phytomedicine; 2021 May 15; 85():153536. PubMed ID: 33765552
    [Abstract] [Full Text] [Related]

  • 18. The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programed Cell Death and Presents Therapeutic Potential in Experimental Cutaneous Leishmaniasis.
    Yamamoto ES, Campos BL, Jesus JA, Laurenti MD, Ribeiro SP, Kallás EG, Rafael-Fernandes M, Santos-Gomes G, Silva MS, Sessa DP, Lago JH, Levy D, Passero LF.
    PLoS One; 2015 May 15; 10(12):e0144946. PubMed ID: 26674781
    [Abstract] [Full Text] [Related]

  • 19. In vitro antileishmanial activity and cytotoxicity of essential oil from Lippia sidoides Cham.
    de Medeiros Md, da Silva AC, Citó AM, Borges AR, de Lima SG, Lopes JA, Figueiredo RC.
    Parasitol Int; 2011 Sep 15; 60(3):237-41. PubMed ID: 21421075
    [Abstract] [Full Text] [Related]

  • 20. Evaluation of antileishmanial activity of eupomatenoid-5, a compound isolated from leaves of Piper regnellii var. pallescens.
    Vendrametto MC, Santos AO, Nakamura CV, Dias Filho BP, Cortez DA, Ueda-Nakamura T.
    Parasitol Int; 2010 Jun 15; 59(2):154-8. PubMed ID: 20064628
    [Abstract] [Full Text] [Related]

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