These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
8. L-Type amino acid transporter 1 (LAT1)-utilizing prodrugs are carrier-selective despite having low affinity for organic anion transporting polypeptides (OATPs). Huttunen J, Gynther M, Vellonen KS, Huttunen KM. Int J Pharm; 2019 Nov 25; 571():118714. PubMed ID: 31610281 [Abstract] [Full Text] [Related]
9. L-Type amino acid transporter 1 (lat1)-mediated targeted delivery of perforin inhibitors. Huttunen KM, Huttunen J, Aufderhaar I, Gynther M, Denny WA, Spicer JA. Int J Pharm; 2016 Feb 10; 498(1-2):205-16. PubMed ID: 26705152 [Abstract] [Full Text] [Related]
10. β-carotene reverses multidrug resistant cancer cells by selectively modulating human P-glycoprotein function. Teng YN, Sheu MJ, Hsieh YW, Wang RY, Chiang YC, Hung CC. Phytomedicine; 2016 Mar 15; 23(3):316-23. PubMed ID: 26969385 [Abstract] [Full Text] [Related]
11. Parguerenes: Marine red alga bromoditerpenes as inhibitors of P-glycoprotein (ABCB1) in multidrug resistant human cancer cells. Huang XC, Sun YL, Salim AA, Chen ZS, Capon RJ. Biochem Pharmacol; 2013 May 01; 85(9):1257-68. PubMed ID: 23415901 [Abstract] [Full Text] [Related]
12. L-type amino acid transporter 1 utilizing prodrugs: How to achieve effective brain delivery and low systemic exposure of drugs. Puris E, Gynther M, Huttunen J, Petsalo A, Huttunen KM. J Control Release; 2017 Sep 10; 261():93-104. PubMed ID: 28662899 [Abstract] [Full Text] [Related]
13. L-Type Amino Acid Transporter 1 Enables the Efficient Brain Delivery of Small-Sized Prodrug across the Blood-Brain Barrier and into Human and Mouse Brain Parenchymal Cells. Montaser AB, Järvinen J, Löffler S, Huttunen J, Auriola S, Lehtonen M, Jalkanen A, Huttunen KM. ACS Chem Neurosci; 2020 Dec 16; 11(24):4301-4315. PubMed ID: 33228353 [Abstract] [Full Text] [Related]
14. Reversal of doxorubicin, etoposide, vinblastine, and taxol resistance in multidrug resistant human sarcoma cells by a polymer of spermine. Gosland MP, Gillespie MN, Tsuboi CP, Tofiq S, Olson JW, Crooks PA, Aziz SM. Cancer Chemother Pharmacol; 1996 Dec 16; 37(6):593-600. PubMed ID: 8612315 [Abstract] [Full Text] [Related]
16. P-glycoprotein, multidrug resistance-associated proteins and human organic anion transporting polypeptide influence the intracellular accumulation of atazanavir. Janneh O, Anwar T, Jungbauer C, Kopp S, Khoo SH, Back DJ, Chiba P. Antivir Ther; 2009 Dec 16; 14(7):965-74. PubMed ID: 19918100 [Abstract] [Full Text] [Related]
17. Amino acid prodrug of quinidine: an approach to circumvent P-glycoprotein mediated cellular efflux. Patel M, Mandava NK, Pal D, Mitra AK. Int J Pharm; 2014 Apr 10; 464(1-2):196-204. PubMed ID: 24440401 [Abstract] [Full Text] [Related]
18. Zosuquidar and an albumin-binding prodrug of zosuquidar reverse multidrug resistance in breast cancer cells of doxorubicin and an albumin-binding prodrug of doxorubicin. Abu Ajaj K, Graeser R, Kratz F. Breast Cancer Res Treat; 2012 Jul 10; 134(1):117-29. PubMed ID: 22228402 [Abstract] [Full Text] [Related]