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Journal Abstract Search

228 related items for PubMed ID: 30176537

  • 1. Discovery of novel vinyl sulfone derivatives as anti-tumor agents with microtubule polymerization inhibitory and vascular disrupting activities.
    Li W, Yin Y, Yao H, Shuai W, Sun H, Xu S, Liu J, Yao H, Zhu Z, Xu J.
    Eur J Med Chem; 2018 Sep 05; 157():1068-1080. PubMed ID: 30176537
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and biological evaluation of pyridine-chalcone derivatives as novel microtubule-destabilizing agents.
    Xu F, Li W, Shuai W, Yang L, Bi Y, Ma C, Yao H, Xu S, Zhu Z, Xu J.
    Eur J Med Chem; 2019 Jul 01; 173():1-14. PubMed ID: 30981112
    [Abstract] [Full Text] [Related]

  • 3. Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site.
    Li W, Sun H, Xu F, Shuai W, Liu J, Xu S, Yao H, Ma C, Zhu Z, Xu J.
    Bioorg Chem; 2019 Apr 01; 85():49-59. PubMed ID: 30599412
    [Abstract] [Full Text] [Related]

  • 4. Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.
    Cao D, Liu Y, Yan W, Wang C, Bai P, Wang T, Tang M, Wang X, Yang Z, Ma B, Ma L, Lei L, Wang F, Xu B, Zhou Y, Yang T, Chen L.
    J Med Chem; 2016 Jun 23; 59(12):5721-39. PubMed ID: 27213819
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 6. Discovery of novel quinazolines as potential anti-tubulin agents occupying three zones of colchicine domain.
    Li W, Yin Y, Shuai W, Xu F, Yao H, Liu J, Cheng K, Xu J, Zhu Z, Xu S.
    Bioorg Chem; 2019 Mar 01; 83():380-390. PubMed ID: 30408650
    [Abstract] [Full Text] [Related]

  • 7. Discovery of novel tubulin/HDAC dual-targeting inhibitors with strong antitumor and antiangiogenic potency.
    Wang Y, Sun M, Wang Y, Qin J, Zhang Y, Pang Y, Yao Y, Yang H, Duan Y.
    Eur J Med Chem; 2021 Dec 05; 225():113790. PubMed ID: 34454126
    [Abstract] [Full Text] [Related]

  • 8. Discovery of 3-(((9H-purin-6-yl)amino)methyl)-4,6-dimethylpyridin-2(1H)-one derivatives as novel tubulin polymerization inhibitors for treatment of cancer.
    Zhang Q, Hu X, Wan G, Wang J, Li L, Wu X, Liu Z, Yu L.
    Eur J Med Chem; 2019 Dec 15; 184():111728. PubMed ID: 31610375
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.
    Pang Y, Lin H, Ou C, Cao Y, An B, Yan J, Li X.
    Eur J Med Chem; 2019 Nov 15; 182():111670. PubMed ID: 31499359
    [Abstract] [Full Text] [Related]

  • 10. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2.
    Lee HY, Chang JY, Nien CY, Kuo CC, Shih KH, Wu CH, Chang CY, Lai WY, Liou JP.
    J Med Chem; 2011 Dec 22; 54(24):8517-25. PubMed ID: 22060033
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of carbamates derived from aminocombretastatin A-4 as vascular disrupting agents.
    Conesa-Milián L, Falomir E, Murga J, Carda M, Meyen E, Liekens S, Alberto Marco J.
    Eur J Med Chem; 2018 Mar 10; 147():183-193. PubMed ID: 29432949
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities.
    Zhang H, Fang X, Meng Q, Mao Y, Xu Y, Fan T, An J, Huang Z.
    Eur J Med Chem; 2018 Sep 05; 157():380-396. PubMed ID: 30099258
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S.
    Eur J Med Chem; 2018 Jan 20; 144():797-816. PubMed ID: 29291446
    [Abstract] [Full Text] [Related]

  • 14. Microtubule inhibitors containing immunostimulatory agents promote cancer immunochemotherapy by inhibiting tubulin polymerization and tryptophan-2,3-dioxygenase.
    Hua S, Chen F, Gou S.
    Eur J Med Chem; 2020 Feb 01; 187():111949. PubMed ID: 31830637
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis, and biological evaluation of 1-substituted -2-aryl imidazoles targeting tubulin polymerization as potential anticancer agents.
    Li L, Quan D, Chen J, Ding J, Zhao J, Lv L, Chen J.
    Eur J Med Chem; 2019 Dec 15; 184():111732. PubMed ID: 31610372
    [Abstract] [Full Text] [Related]

  • 16. N-(1'-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia.
    Salum LB, Mascarello A, Canevarolo RR, Altei WF, Laranjeira AB, Neuenfeldt PD, Stumpf TR, Chiaradia-Delatorre LD, Vollmer LL, Daghestani HN, de Souza Melo CP, Silveira AB, Leal PC, Frederico MJ, do Nascimento LF, Santos AR, Andricopulo AD, Day BW, Yunes RA, Vogt A, Yunes JA, Nunes RJ.
    Eur J Med Chem; 2015 Dec 15; 96():504-18. PubMed ID: 25951294
    [Abstract] [Full Text] [Related]

  • 17. Evaluation of the antitumor activity of NOV202, a novel microtubule targeting and vascular disrupting agent.
    Rickardson L, Kutvonen E, Orasniemi S, Högberg M, Kallio MJ, Rehnmark S.
    Drug Des Devel Ther; 2017 Dec 15; 11():1335-1351. PubMed ID: 28496304
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and bioevaluation of diarylpyrazoles as antiproliferative agents.
    Wang C, Yang S, Du J, Ni J, Wu Y, Wang J, Guan Q, Zuo D, Bao K, Wu Y, Zhang W.
    Eur J Med Chem; 2019 Jun 01; 171():1-10. PubMed ID: 30901597
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity.
    Wang F, Yang Z, Liu Y, Ma L, Wu Y, He L, Shao M, Yu K, Wu W, Pu Y, Nie C, Chen L.
    Bioorg Med Chem; 2015 Jul 01; 23(13):3337-50. PubMed ID: 25937236
    [Abstract] [Full Text] [Related]

  • 20. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X.
    Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540
    [Abstract] [Full Text] [Related]

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