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Journal Abstract Search

814 related items for PubMed ID: 30197030

  • 1. (E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction.
    Wang G, Peng Z, Peng S, Qiu J, Li Y, Lan Y.
    Bioorg Med Chem Lett; 2018 Nov 01; 28(20):3350-3355. PubMed ID: 30197030
    [Abstract] [Full Text] [Related]

  • 2. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 01; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 3. Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors.
    Sana S, Tokala R, Bajaj DM, Nagesh N, Bokara KK, Kiranmai G, Lakshmi UJ, Vadlamani S, Talla V, Shankaraiah N.
    Bioorg Chem; 2019 Dec 01; 93():103317. PubMed ID: 31586714
    [Abstract] [Full Text] [Related]

  • 4. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.
    Yang F, He CP, Diao PC, Hong KH, Rao JJ, Zhao PL.
    Bioorg Med Chem Lett; 2019 Jan 01; 29(1):22-27. PubMed ID: 30448234
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, biological evaluation and molecular docking studies of a new series of chalcones containing naphthalene moiety as anticancer agents.
    Wang G, Qiu J, Xiao X, Cao A, Zhou F.
    Bioorg Chem; 2018 Feb 01; 76():249-257. PubMed ID: 29197743
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological evaluation of imidazo[2,1-b][1,3,4]thiadiazole-linked oxindoles as potent tubulin polymerization inhibitors.
    Kamal A, Rao MP, Das P, Swapna P, Polepalli S, Nimbarte VD, Mullagiri K, Kovvuri J, Jain N.
    ChemMedChem; 2014 Jul 01; 9(7):1463-75. PubMed ID: 24715721
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding site.
    Wang G, Liu W, Gong Z, Huang Y, Li Y, Peng Z.
    J Enzyme Inhib Med Chem; 2020 Dec 01; 35(1):139-144. PubMed ID: 31724435
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis, and biological evaluation of novel 2,3-Di-O-Aryl/Alkyl sulfonate derivatives of l-ascorbic acid: Efficient access to novel anticancer agents via in vitro screening, tubulin polymerization inhibition, molecular docking study and ADME predictions.
    Deshmukh SR, Nalkar AS, Sarkate AP, Tiwari SV, Lokwani DK, Thopate SR.
    Bioorg Chem; 2024 Jun 01; 147():107402. PubMed ID: 38688199
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors.
    Khelifi I, Naret T, Renko D, Hamze A, Bernadat G, Bignon J, Lenoir C, Dubois J, Brion JD, Provot O, Alami M.
    Eur J Med Chem; 2017 Feb 15; 127():1025-1034. PubMed ID: 28166995
    [Abstract] [Full Text] [Related]

  • 10. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):640-658. PubMed ID: 33588683
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS, Tabeshpour J, Mirzaei S, Golmakaniyoon S, Tayarani-Najaran Z, Ghasemi A, Ghodsi R.
    Arch Pharm (Weinheim); 2019 Jun 15; 352(6):e1800307. PubMed ID: 31012156
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and structure-activity relationship of 3,6-diaryl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines as novel tubulin inhibitors.
    Xu Q, Bao K, Sun M, Xu J, Wang Y, Tian H, Zuo D, Guan Q, Wu Y, Zhang W.
    Sci Rep; 2017 Sep 20; 7(1):11997. PubMed ID: 28931885
    [Abstract] [Full Text] [Related]

  • 13. Design and synthesis of aminostilbene-arylpropenones as tubulin polymerization inhibitors.
    Kamal A, Kumar GB, Polepalli S, Shaik AB, Reddy VS, Reddy MK, Reddy ChR, Mahesh R, Kapure JS, Jain N.
    ChemMedChem; 2014 Nov 20; 9(11):2565-79. PubMed ID: 25146959
    [Abstract] [Full Text] [Related]

  • 14. Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization.
    Jadala C, Sathish M, Anchi P, Tokala R, Lakshmi UJ, Reddy VG, Shankaraiah N, Godugu C, Kamal A.
    ChemMedChem; 2019 Dec 17; 14(24):2052-2060. PubMed ID: 31674147
    [Abstract] [Full Text] [Related]

  • 15. Synthesis, Anticancer Activity and Molecular Modeling Studies of Novel Chalcone Derivatives Containing Indole and Naphthalene Moieties as Tubulin Polymerization Inhibitors.
    Wang G, Peng Z, Li Y.
    Chem Pharm Bull (Tokyo); 2019 Jul 01; 67(7):725-728. PubMed ID: 30982797
    [Abstract] [Full Text] [Related]

  • 16. 1H-benzimidazole-2-yl hydrazones as tubulin-targeting agents: Synthesis, structural characterization, anthelmintic activity and antiproliferative activity against MCF-7 breast carcinoma cells and molecular docking studies.
    Anichina K, Argirova M, Tzoneva R, Uzunova V, Mavrova A, Vuchev D, Popova-Daskalova G, Fratev F, Guncheva M, Yancheva D.
    Chem Biol Interact; 2021 Aug 25; 345():109540. PubMed ID: 34139148
    [Abstract] [Full Text] [Related]

  • 17. Synthesis, biological evaluation and molecular docking studies of aminochalcone derivatives as potential anticancer agents by targeting tubulin colchicine binding site.
    Wang G, Peng Z, Zhang J, Qiu J, Xie Z, Gong Z.
    Bioorg Chem; 2018 Aug 25; 78():332-340. PubMed ID: 29627654
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors.
    Rahimzadeh Oskuei S, Mirzaei S, Reza Jafari-Nik M, Hadizadeh F, Eisvand F, Mosaffa F, Ghodsi R.
    Bioorg Chem; 2021 Jul 25; 112():104904. PubMed ID: 33933802
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors.
    Wang G, Peng F, Cao D, Yang Z, Han X, Liu J, Wu W, He L, Ma L, Chen J, Sang Y, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2013 Nov 01; 21(21):6844-54. PubMed ID: 23993668
    [Abstract] [Full Text] [Related]

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