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Journal Abstract Search

204 related items for PubMed ID: 30206768

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  • 2. Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo.
    Zhou GB, Kang H, Wang L, Gao L, Liu P, Xie J, Zhang FX, Weng XQ, Shen ZX, Chen J, Gu LJ, Yan M, Zhang DE, Chen SJ, Wang ZY, Chen Z.
    Blood; 2007 Apr 15; 109(8):3441-50. PubMed ID: 17197433
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  • 3. Targeting of AML1-ETO in t(8;21) leukemia by oridonin generates a tumor suppressor-like protein.
    Zhen T, Wu CF, Liu P, Wu HY, Zhou GB, Lu Y, Liu JX, Liang Y, Li KK, Wang YY, Xie YY, He MM, Cao HM, Zhang WN, Chen LM, Petrie K, Chen SJ, Chen Z.
    Sci Transl Med; 2012 Mar 28; 4(127):127ra38. PubMed ID: 22461642
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  • 7. Combination of eriocalyxin B and homoharringtonine exerts synergistic anti-tumor effects against t(8;21) AML.
    Lei YC, Chen XJ, Dai YT, Dai B, Wang JY, Li MH, Liu P, Liu H, Wang KK, Jiang L, Chen B.
    Acta Pharmacol Sin; 2024 Mar 28; 45(3):633-645. PubMed ID: 38017299
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  • 8. Polyphyllin I Inhibits Proliferation and Induces Apoptosis by Downregulating AML1-ETO and Suppressing C-KIT/Akt Signaling in t(8;21) Acute Myeloid Leukemia.
    Chai Y, Si Y, Xu J, Xiang Y, Zhao H, Si Y, Zhang T, Liu Y.
    Chem Biodivers; 2018 Nov 28; 15(11):e1800314. PubMed ID: 30194712
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  • 9. C-KIT mutation cooperates with full-length AML1-ETO to induce acute myeloid leukemia in mice.
    Wang YY, Zhao LJ, Wu CF, Liu P, Shi L, Liang Y, Xiong SM, Mi JQ, Chen Z, Ren R, Chen SJ.
    Proc Natl Acad Sci U S A; 2011 Feb 08; 108(6):2450-5. PubMed ID: 21262832
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  • 10. AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: implication in stepwise leukemogenesis and response to Gleevec.
    Wang YY, Zhou GB, Yin T, Chen B, Shi JY, Liang WX, Jin XL, You JH, Yang G, Shen ZX, Chen J, Xiong SM, Chen GQ, Xu F, Liu YW, Chen Z, Chen SJ.
    Proc Natl Acad Sci U S A; 2005 Jan 25; 102(4):1104-9. PubMed ID: 15650049
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  • 11. Homoharringtonine is synergistically lethal with BCL-2 inhibitor APG-2575 in acute myeloid leukemia.
    Wei W, Huang S, Ling Q, Mao S, Qian Y, Ye W, Li F, Pan J, Lin X, Huang J, Huang X, Zhai Y, Sun J, Jin J.
    J Transl Med; 2022 Jul 06; 20(1):299. PubMed ID: 35794605
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  • 12. Oridonin Synergistically Enhances the Pro-Apoptotic Effect of Venetoclax on Acute Myeloid Leukemia Cells by Inhibiting AKT Signaling.
    Chen L, Li D, Guo X, Cheng C, Wei X.
    Front Biosci (Landmark Ed); 2023 Sep 06; 28(9):195. PubMed ID: 37796705
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  • 13. A novel combination of oridonin and valproic acid in enhancement of apoptosis induction of HL-60 leukemia cells.
    Shi M, Ren X, Wang X, Wang H, Liu G, Yuan X, Zheng S, Yu L, Pan S, Song G, Guo Q, Li L, Zhang X, Zhang Z, Ding H, Jiang G.
    Int J Oncol; 2016 Feb 06; 48(2):734-46. PubMed ID: 26676928
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  • 15. Abivertinib, a novel BTK inhibitor: Anti-Leukemia effects and synergistic efficacy with homoharringtonine in acute myeloid leukemia.
    Huang S, Pan J, Jin J, Li C, Li X, Huang J, Huang X, Yan X, Li F, Yu M, Hu C, Jin J, Xu Y, Ling Q, Ye W, Wang Y, Jin J.
    Cancer Lett; 2019 Oct 01; 461():132-143. PubMed ID: 31310800
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  • 16. High expression of c-kit mRNA predicts unfavorable outcome in adult patients with t(8;21) acute myeloid leukemia.
    Gao X, Lin J, Gao L, Deng A, Lu X, Li Y, Wang L, Yu L.
    PLoS One; 2015 Oct 01; 10(4):e0124241. PubMed ID: 25860287
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  • 19. The antitumor activity of homoharringtonine against human mast cells harboring the KIT D816V mutation.
    Jin Y, Lu Z, Cao K, Zhu Y, Chen Q, Zhu F, Qian C, Pan J.
    Mol Cancer Ther; 2010 Jan 01; 9(1):211-23. PubMed ID: 20053766
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  • 20. Oridonin Could Inhibit Inflammation and T-cell Immunoglobulin and Mucin-3/Galectin-9 (TIM-3/Gal-9) Autocrine Loop in the Acute Myeloid Leukemia Cell Line (U937) as Compared to Doxorubicin.
    Nasri F, Sadeghi F, Behranvand N, Samei A, Bolouri MR, Azari T, Abdollahi E, Ghazizadeh F, Motevalian M, Hassan ZM, Falak R.
    Iran J Allergy Asthma Immunol; 2020 Dec 19; 19(6):602-611. PubMed ID: 33463129
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