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Journal Abstract Search

174 related items for PubMed ID: 30209037

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  • 2. In Vitro Metabolism by Aldehyde Oxidase Leads to Poor Pharmacokinetic Profile in Rats for c-Met Inhibitor MET401.
    Zhang JW, Deng HB, Zhang CY, Dai JQ, Li Q, Zheng QG, Wan HX, Yu HP, He F, Xu YC, Zhao S, Zhang JYJ.
    Eur J Drug Metab Pharmacokinet; 2019 Oct; 44(5):669-680. PubMed ID: 31030415
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  • 4. Identification of 3-substituted-6-(1-(1H-[1,2,3]triazolo[4,5-b]pyrazin-1-yl)ethyl)quinoline derivatives as highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitors via metabolite profiling-based structural optimization.
    Zhao F, Zhang LD, Hao Y, Chen N, Bai R, Wang YJ, Zhang CC, Li GS, Hao LJ, Shi C, Zhang J, Mao Y, Fan Y, Xia GX, Yu JX, Liu YJ.
    Eur J Med Chem; 2017 Jul 07; 134():147-158. PubMed ID: 28411455
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  • 5. Species-Specific Involvement of Aldehyde Oxidase and Xanthine Oxidase in the Metabolism of the Pyrimidine-Containing mGlu5-Negative Allosteric Modulator VU0424238 (Auglurant).
    Crouch RD, Blobaum AL, Felts AS, Conn PJ, Lindsley CW.
    Drug Metab Dispos; 2017 Dec 07; 45(12):1245-1259. PubMed ID: 28939686
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  • 11. Oxidative metabolic pathway of lenvatinib mediated by aldehyde oxidase.
    Inoue K, Mizuo H, Kawaguchi S, Fukuda K, Kusano K, Yoshimura T.
    Drug Metab Dispos; 2014 Aug 07; 42(8):1326-33. PubMed ID: 24914245
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  • 12. Aldehyde oxidase activity and inhibition in hepatocytes and cytosolic fractions from mouse, rat, monkey and human.
    Sahi J, Khan KK, Black CB.
    Drug Metab Lett; 2008 Aug 07; 2(3):176-83. PubMed ID: 19356090
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  • 15. Effect of structural variation on aldehyde oxidase-catalyzed oxidation of zoniporide.
    Dalvie D, Sun H, Xiang C, Hu Q, Jiang Y, Kang P.
    Drug Metab Dispos; 2012 Aug 07; 40(8):1575-87. PubMed ID: 22587988
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  • 19. Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach.
    Adusumalli S, Jamwal R, Obach RS, Ryder TF, Leggio L, Akhlaghi F.
    Drug Metab Dispos; 2019 Aug 07; 47(8):874-882. PubMed ID: 31182423
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  • 20. Evaluation of Deuterium-Labeled JNJ38877605: Pharmacokinetic, Metabolic, and in Vivo Antitumor Profiles.
    Zhan Z, Peng X, Sun Y, Ai J, Duan W.
    Chem Res Toxicol; 2018 Nov 19; 31(11):1213-1218. PubMed ID: 30284817
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