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Journal Abstract Search

198 related items for PubMed ID: 30217986

  • 1. AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage.
    Fang CC, Wu CF, Liao YJ, Huang SF, Chen M, Chen YA.
    Sci Rep; 2018 Sep 14; 8(1):13802. PubMed ID: 30217986
    [Abstract] [Full Text] [Related]

  • 2. Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice.
    Martínez-Chantar ML, Vázquez-Chantada M, Ariz U, Martínez N, Varela M, Luka Z, Capdevila A, Rodríguez J, Aransay AM, Matthiesen R, Yang H, Calvisi DF, Esteller M, Fraga M, Lu SC, Wagner C, Mato JM.
    Hepatology; 2008 Apr 14; 47(4):1191-9. PubMed ID: 18318442
    [Abstract] [Full Text] [Related]

  • 3. Induction of GNMT by 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranoside through proteasome-independent MYC downregulation in hepatocellular carcinoma.
    Kant R, Yen CH, Hung JH, Lu CK, Tung CY, Chang PC, Chen YH, Tyan YC, Chen YA.
    Sci Rep; 2019 Feb 13; 9(1):1968. PubMed ID: 30760754
    [Abstract] [Full Text] [Related]

  • 4. Characterization of the GNMT-HectH9-PREX2 tripartite relationship in the pathogenesis of hepatocellular carcinoma.
    Li CH, Yen CH, Chen YF, Lee KJ, Fang CC, Zhang X, Lai CC, Huang SF, Lin HK, Arthur Chen YM.
    Int J Cancer; 2017 May 15; 140(10):2284-2297. PubMed ID: 28205209
    [Abstract] [Full Text] [Related]

  • 5. A DNA methylation signature associated with the epigenetic repression of glycine N-methyltransferase in human hepatocellular carcinoma.
    Huidobro C, Toraño EG, Fernández AF, Urdinguio RG, Rodríguez RM, Ferrero C, Martínez-Camblor P, Boix L, Bruix J, García-Rodríguez JL, Varela-Rey M, Mato JM, Martínez-Chantar ML, Fraga MF.
    J Mol Med (Berl); 2013 Aug 15; 91(8):939-50. PubMed ID: 23475283
    [Abstract] [Full Text] [Related]

  • 6. Gene Expression and DNA Methylation Alterations in the Glycine N-Methyltransferase Gene in Diet-Induced Nonalcoholic Fatty Liver Disease-Associated Carcinogenesis.
    Borowa-Mazgaj B, de Conti A, Tryndyak V, Steward CR, Jimenez L, Melnyk S, Seneshaw M, Mirshahi F, Rusyn I, Beland FA, Sanyal AJ, Pogribny IP.
    Toxicol Sci; 2019 Aug 01; 170(2):273-282. PubMed ID: 31086990
    [Abstract] [Full Text] [Related]

  • 7. MicroRNA-224 down-regulates Glycine N-methyltransferase gene expression in Hepatocellular Carcinoma.
    Hung JH, Li CH, Yeh CH, Huang PC, Fang CC, Chen YF, Lee KJ, Chou CH, Cheng HY, Huang HD, Chen M, Tsai TF, Lin AM, Yen CH, Tsou AP, Tyan YC, Chen YA.
    Sci Rep; 2018 Aug 16; 8(1):12284. PubMed ID: 30115977
    [Abstract] [Full Text] [Related]

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  • 9. Downregulation of Methionine Cycle Genes MAT1A and GNMT Enriches Protein-Associated Translation Process and Worsens Hepatocellular Carcinoma Prognosis.
    Chen PM, Tsai CH, Huang CC, Hwang HH, Li JR, Liu CC, Ko HA, Chiang EI.
    Int J Mol Sci; 2022 Jan 01; 23(1):. PubMed ID: 35008908
    [Abstract] [Full Text] [Related]

  • 10. A novel role of the tumor suppressor GNMT in cellular defense against DNA damage.
    Wang YC, Lin WL, Lin YJ, Tang FY, Chen YM, Chiang EP.
    Int J Cancer; 2014 Feb 15; 134(4):799-810. PubMed ID: 23922098
    [Abstract] [Full Text] [Related]

  • 11. MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis.
    Fernández-Ramos D, Fernández-Tussy P, Lopitz-Otsoa F, Gutiérrez-de-Juan V, Navasa N, Barbier-Torres L, Zubiete-Franco I, Simón J, Fernández AF, Arbelaiz A, Aransay AM, Lavín JL, Beraza N, Perugorria MJ, Banales JM, Villa E, Fraga MF, Anguita J, Avila MA, Berasain C, Iruzibieta P, Crespo J, Lu SC, Varela-Rey M, Mato JM, Delgado TC, Martínez-Chantar ML.
    Cell Death Dis; 2018 Sep 20; 9(10):958. PubMed ID: 30237481
    [Abstract] [Full Text] [Related]

  • 12. Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma: Implications of the gender disparity in liver cancer susceptibility.
    Liao YJ, Liu SP, Lee CM, Yen CH, Chuang PC, Chen CY, Tsai TF, Huang SF, Lee YH, Chen YM.
    Int J Cancer; 2009 Feb 15; 124(4):816-26. PubMed ID: 19035462
    [Abstract] [Full Text] [Related]

  • 13. Identification of 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranoside as a Glycine N-Methyltransferase Enhancer by High-Throughput Screening of Natural Products Inhibits Hepatocellular Carcinoma.
    Kant R, Yen CH, Lu CK, Lin YC, Li JH, Chen YM.
    Int J Mol Sci; 2016 May 04; 17(5):. PubMed ID: 27153064
    [Abstract] [Full Text] [Related]

  • 14. Tumor suppressor gene glycine N-methyltransferase and its potential in liver disorders and hepatocellular carcinoma.
    Chen M, Yang MH, Chang MM, Tyan YC, Chen YA.
    Toxicol Appl Pharmacol; 2019 Sep 01; 378():114607. PubMed ID: 31170416
    [Abstract] [Full Text] [Related]

  • 15. Dysregulated transmethylation leading to hepatocellular carcinoma compromises redox homeostasis and glucose formation.
    Hughey CC, James FD, Wang Z, Goelzer M, Wasserman DH.
    Mol Metab; 2019 May 01; 23():1-13. PubMed ID: 30850319
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of natural killer cells protects the liver against acute injury in the absence of glycine N-methyltransferase.
    Gomez-Santos L, Luka Z, Wagner C, Fernandez-Alvarez S, Lu SC, Mato JM, Martinez-Chantar ML, Beraza N.
    Hepatology; 2012 Aug 01; 56(2):747-59. PubMed ID: 22392635
    [Abstract] [Full Text] [Related]

  • 17. Discovery of an Orally Efficacious MYC Inhibitor for Liver Cancer Using a GNMT-Based High-Throughput Screening System and Structure-Activity Relationship Analysis.
    Kant R, Yang MH, Tseng CH, Yen CH, Li WY, Tyan YC, Chen M, Tzeng CC, Chen WC, You K, Wang WC, Chen YL, Chen YA.
    J Med Chem; 2021 Jul 08; 64(13):8992-9009. PubMed ID: 34132534
    [Abstract] [Full Text] [Related]

  • 18. Preferential targeting of disseminated liver tumors using a recombinant adeno-associated viral vector.
    Della Peruta M, Badar A, Rosales C, Chokshi S, Kia A, Nathwani D, Galante E, Yan R, Arstad E, Davidoff AM, Williams R, Lythgoe MF, Nathwani AC.
    Hum Gene Ther; 2015 Feb 08; 26(2):94-103. PubMed ID: 25569358
    [Abstract] [Full Text] [Related]

  • 19. Functional characterization of glycine N-methyltransferase and its interactive protein DEPDC6/DEPTOR in hepatocellular carcinoma.
    Yen CH, Lu YC, Li CH, Lee CM, Chen CY, Cheng MY, Huang SF, Chen KF, Cheng AL, Liao LY, Lee YH, Chen YM.
    Mol Med; 2012 Mar 30; 18(1):286-96. PubMed ID: 22160218
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