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Journal Abstract Search

172 related items for PubMed ID: 30226440

  • 1. c-Myc Is a Major Determinant for Antitumor Activity of Aurora A Kinase Inhibitor MLN8237 in Thyroid Cancer.
    Li Y, Li X, Pu J, Yang Q, Guan H, Ji M, Shi B, Chen M, Hou P.
    Thyroid; 2018 Dec; 28(12):1642-1654. PubMed ID: 30226440
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of Aurora A Kinase in Combination with Chemotherapy Induces Synthetic Lethality and Overcomes Chemoresistance in Myc-Overexpressing Lymphoma.
    Park SI, Lin CP, Ren N, Angus SP, Dittmer DP, Foote M, Parton T, Bhatt AP, Fedoriw YD, Roth DP, Cann ML, Johnson GL, Damania B.
    Target Oncol; 2019 Oct; 14(5):563-575. PubMed ID: 31429028
    [Abstract] [Full Text] [Related]

  • 3. Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models.
    Kogiso M, Qi L, Braun FK, Injac SG, Zhang L, Du Y, Zhang H, Lin FY, Zhao S, Lindsay H, Su JM, Baxter PA, Adesina AM, Liao D, Qian MG, Berg S, Muscal JA, Li XN.
    Clin Cancer Res; 2018 May 01; 24(9):2159-2170. PubMed ID: 29463553
    [Abstract] [Full Text] [Related]

  • 4. A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer.
    Dauch D, Rudalska R, Cossa G, Nault JC, Kang TW, Wuestefeld T, Hohmeyer A, Imbeaud S, Yevsa T, Hoenicke L, Pantsar T, Bozko P, Malek NP, Longerich T, Laufer S, Poso A, Zucman-Rossi J, Eilers M, Zender L.
    Nat Med; 2016 Jul 01; 22(7):744-53. PubMed ID: 27213815
    [Abstract] [Full Text] [Related]

  • 5. Targeting Aurora kinase-A downregulates cell proliferation and angiogenesis in neuroblastoma.
    Romain C, Paul P, Kim KW, Lee S, Qiao J, Chung DH.
    J Pediatr Surg; 2014 Jan 01; 49(1):159-65. PubMed ID: 24439602
    [Abstract] [Full Text] [Related]

  • 6. The aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cells.
    Sehdev V, Peng D, Soutto M, Washington MK, Revetta F, Ecsedy J, Zaika A, Rau TT, Schneider-Stock R, Belkhiri A, El-Rifai W.
    Mol Cancer Ther; 2012 Mar 01; 11(3):763-74. PubMed ID: 22302096
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of Aurora A enhances radiosensitivity in selected lung cancer cell lines.
    Liu N, Wang YA, Sun Y, Ecsedy J, Sun J, Li X, Wang P.
    Respir Res; 2019 Oct 23; 20(1):230. PubMed ID: 31647033
    [Abstract] [Full Text] [Related]

  • 8. Preclinical testing of selective Aurora kinase inhibitors on a medullary thyroid carcinoma-derived cell line.
    Tuccilli C, Baldini E, Prinzi N, Morrone S, Sorrenti S, Filippini A, Catania A, Alessandrini S, Rendina R, Coccaro C, D'Armiento M, Ulisse S.
    Endocrine; 2016 May 23; 52(2):287-95. PubMed ID: 26215279
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
    Yuan CX, Zhou ZW, Yang YX, He ZX, Zhang X, Wang D, Yang T, Wang NJ, Zhao RJ, Zhou SF.
    Drug Des Devel Ther; 2015 May 23; 9():487-508. PubMed ID: 25609923
    [Abstract] [Full Text] [Related]

  • 10. Combination of Eribulin and Aurora A Inhibitor MLN8237 Prevents Metastatic Colonization and Induces Cytotoxic Autophagy in Breast Cancer.
    Kozyreva VK, Kiseleva AA, Ice RJ, Jones BC, Loskutov YV, Matalkah F, Smolkin MB, Marinak K, Livengood RH, Salkeni MA, Wen S, Hazard HW, Layne GP, Walsh CM, Cantrell PS, Kilby GW, Mahavadi S, Shah N, Pugacheva EN.
    Mol Cancer Ther; 2016 Aug 23; 15(8):1809-22. PubMed ID: 27235164
    [Abstract] [Full Text] [Related]

  • 11. Aurora inhibitor MLN8237 in combination with docetaxel enhances apoptosis and anti-tumor activity in mantle cell lymphoma.
    Qi W, Cooke LS, Liu X, Rimsza L, Roe DJ, Manziolli A, Persky DO, Miller TP, Mahadevan D.
    Biochem Pharmacol; 2011 Apr 01; 81(7):881-90. PubMed ID: 21291867
    [Abstract] [Full Text] [Related]

  • 12. Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells.
    Ding YH, Zhou ZW, Ha CF, Zhang XY, Pan ST, He ZX, Edelman JL, Wang D, Yang YX, Zhang X, Duan W, Yang T, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Apr 01; 9():425-64. PubMed ID: 25624750
    [Abstract] [Full Text] [Related]

  • 13. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP, Yang YX, Liu QL, Pan ST, He ZX, Zhang X, Yang T, Chen XW, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Apr 01; 9():1627-52. PubMed ID: 25834401
    [Abstract] [Full Text] [Related]

  • 14. Effects of selective inhibitors of Aurora kinases on anaplastic thyroid carcinoma cell lines.
    Baldini E, Tuccilli C, Prinzi N, Sorrenti S, Antonelli A, Gnessi L, Morrone S, Moretti C, Bononi M, Arlot-Bonnemains Y, D'Armiento M, Ulisse S.
    Endocr Relat Cancer; 2014 Oct 01; 21(5):797-811. PubMed ID: 25074669
    [Abstract] [Full Text] [Related]

  • 15. A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma.
    Görgün G, Calabrese E, Hideshima T, Ecsedy J, Perrone G, Mani M, Ikeda H, Bianchi G, Hu Y, Cirstea D, Santo L, Tai YT, Nahar S, Zheng M, Bandi M, Carrasco RD, Raje N, Munshi N, Richardson P, Anderson KC.
    Blood; 2010 Jun 24; 115(25):5202-13. PubMed ID: 20382844
    [Abstract] [Full Text] [Related]

  • 16. Cisplatin-resistant cancer cells are sensitive to Aurora kinase A inhibition by alisertib.
    Wang L, Arras J, Katsha A, Hamdan S, Belkhiri A, Ecsedy J, El-Rifai W.
    Mol Oncol; 2017 Aug 24; 11(8):981-995. PubMed ID: 28417568
    [Abstract] [Full Text] [Related]

  • 17. Initial testing of the aurora kinase A inhibitor MLN8237 by the Pediatric Preclinical Testing Program (PPTP).
    Maris JM, Morton CL, Gorlick R, Kolb EA, Lock R, Carol H, Keir ST, Reynolds CP, Kang MH, Wu J, Smith MA, Houghton PJ.
    Pediatr Blood Cancer; 2010 Jul 15; 55(1):26-34. PubMed ID: 20108338
    [Abstract] [Full Text] [Related]

  • 18. Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer.
    Pitts TM, Bradshaw-Pierce EL, Bagby SM, Hyatt SL, Selby HM, Spreafico A, Tentler JJ, McPhillips K, Klauck PJ, Capasso A, Diamond JR, Davis SL, Tan AC, Arcaroli JJ, Purkey A, Messersmith WA, Ecsedy JA, Eckhardt SG.
    Oncotarget; 2016 Aug 02; 7(31):50290-50301. PubMed ID: 27385211
    [Abstract] [Full Text] [Related]

  • 19. Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition.
    Wen QJ, Yang Q, Goldenson B, Malinge S, Lasho T, Schneider RK, Breyfogle LJ, Schultz R, Gilles L, Koppikar P, Abdel-Wahab O, Pardanani A, Stein B, Gurbuxani S, Mullally A, Levine RL, Tefferi A, Crispino JD.
    Nat Med; 2015 Dec 02; 21(12):1473-80. PubMed ID: 26569382
    [Abstract] [Full Text] [Related]

  • 20. The investigational Aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell-cycle progression in malignant bladder cancer cells in vitro and in vivo.
    Zhou N, Singh K, Mir MC, Parker Y, Lindner D, Dreicer R, Ecsedy JA, Zhang Z, Teh BT, Almasan A, Hansel DE.
    Clin Cancer Res; 2013 Apr 01; 19(7):1717-28. PubMed ID: 23403633
    [Abstract] [Full Text] [Related]

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