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183 related items for PubMed ID: 30243240
21. Brain uptake of ketoprofen-lysine prodrug in rats. Gynther M, Jalkanen A, Lehtonen M, Forsberg M, Laine K, Ropponen J, Leppänen J, Knuuti J, Rautio J. Int J Pharm; 2010 Oct 31; 399(1-2):121-8. PubMed ID: 20727958 [Abstract] [Full Text] [Related]
22. Amino Acid Promoieties Alter Valproic Acid Pharmacokinetics and Enable Extended Brain Exposure. Gynther M, Peura L, Vernerová M, Leppänen J, Kärkkäinen J, Lehtonen M, Rautio J, Huttunen KM. Neurochem Res; 2016 Oct 31; 41(10):2797-2809. PubMed ID: 27412117 [Abstract] [Full Text] [Related]
24. In vitro hydrolysis and transesterification of CDP323, an α4β1/α4β7 integrin antagonist ester prodrug. Chanteux H, Rosa M, Delatour C, Prakash C, Smith S, Nicolas JM. Drug Metab Dispos; 2014 Jan 31; 42(1):153-61. PubMed ID: 24179032 [Abstract] [Full Text] [Related]
29. Down-regulation of carboxylesterases 1 and 2 plays an important role in prodrug metabolism in immunological liver injury rats. Zhang C, Xu Y, Gao P, Lu J, Li X, Liu D. Int Immunopharmacol; 2015 Feb 31; 24(2):153-158. PubMed ID: 25499727 [Abstract] [Full Text] [Related]
31. In vitro and in vivo evaluations of the metabolism, pharmacokinetics, and bioavailability of ester prodrugs of L-767,679, a potent fibrinogen receptor antagonist: an approach for the selection of a prodrug candidate. Prueksaritanont T, Gorham LM, Breslin MJ, Hutchinson JH, Hartman GD, Vyas KP, Baillie TA. Drug Metab Dispos; 1997 Aug 31; 25(8):978-84. PubMed ID: 9280406 [Abstract] [Full Text] [Related]
34. Hydrolytic biotransformation of the bumetanide ester prodrug DIMAEB to bumetanide by esterases in neonatal human and rat serum and neonatal rat brain-A new treatment strategy for neonatal seizures? Theilmann W, Brandt C, Bohnhorst B, Winstroth AM, Das AM, Gramer M, Kipper A, Kalesse M, Löscher W. Epilepsia; 2021 Jan 31; 62(1):269-278. PubMed ID: 33140458 [Abstract] [Full Text] [Related]
38. [Evaluation of the Oral Absorption of Ester-type Prodrugs]. Ohura K. Yakugaku Zasshi; 2020 Jan 31; 140(3):369-376. PubMed ID: 32115554 [Abstract] [Full Text] [Related]
39. Stereospecific activity and nature of metabolizing esterases for propranolol prodrug in hairless mouse skin, liver and plasma. Ahmed S, Imai T, Yoshigae Y, Otagiri M. Life Sci; 1997 Jan 31; 61(19):1879-87. PubMed ID: 9364192 [Abstract] [Full Text] [Related]