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Journal Abstract Search

1182 related items for PubMed ID: 30253279

  • 1. Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.
    Felszeghy S, Viiri J, Paterno JJ, Hyttinen JMT, Koskela A, Chen M, Leinonen H, Tanila H, Kivinen N, Koistinen A, Toropainen E, Amadio M, Smedowski A, Reinisalo M, Winiarczyk M, Mackiewicz J, Mutikainen M, Ruotsalainen AK, Kettunen M, Jokivarsi K, Sinha D, Kinnunen K, Petrovski G, Blasiak J, Bjørkøy G, Koskelainen A, Skottman H, Urtti A, Salminen A, Kannan R, Ferrington DA, Xu H, Levonen AL, Tavi P, Kauppinen A, Kaarniranta K.
    Redox Biol; 2019 Jan; 20():1-12. PubMed ID: 30253279
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  • 2. Mitophagy in the Retinal Pigment Epithelium of Dry Age-Related Macular Degeneration Investigated in the NFE2L2/PGC-1α-/- Mouse Model.
    Sridevi Gurubaran I, Viiri J, Koskela A, Hyttinen JMT, Paterno JJ, Kis G, Antal M, Urtti A, Kauppinen A, Felszeghy S, Kaarniranta K.
    Int J Mol Sci; 2020 Mar 13; 21(6):. PubMed ID: 32183173
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  • 3. Pgc-1α repression and high-fat diet induce age-related macular degeneration-like phenotypes in mice.
    Zhang M, Chu Y, Mowery J, Konkel B, Galli S, Theos AC, Golestaneh N.
    Dis Model Mech; 2018 Aug 16; 11(9):. PubMed ID: 29925537
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  • 6. PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis.
    Kaarniranta K, Kajdanek J, Morawiec J, Pawlowska E, Blasiak J.
    Int J Mol Sci; 2018 Aug 07; 19(8):. PubMed ID: 30087287
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  • 7. Mitochondrial damage and clearance in retinal pigment epithelial cells.
    Gurubaran IS.
    Acta Ophthalmol; 2024 Mar 07; 102 Suppl 282():3-53. PubMed ID: 38467968
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  • 8. Repressed SIRT1/PGC-1α pathway and mitochondrial disintegration in iPSC-derived RPE disease model of age-related macular degeneration.
    Golestaneh N, Chu Y, Cheng SK, Cao H, Poliakov E, Berinstein DM.
    J Transl Med; 2016 Dec 20; 14(1):344. PubMed ID: 27998274
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  • 10. PGC-1α Induces Human RPE Oxidative Metabolism and Antioxidant Capacity.
    Iacovelli J, Rowe GC, Khadka A, Diaz-Aguilar D, Spencer C, Arany Z, Saint-Geniez M.
    Invest Ophthalmol Vis Sci; 2016 Mar 20; 57(3):1038-51. PubMed ID: 26962700
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  • 13. Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD.
    Gupta U, Ghosh S, Wallace CT, Shang P, Xin Y, Nair AP, Yazdankhah M, Strizhakova A, Ross MA, Liu H, Hose S, Stepicheva NA, Chowdhury O, Nemani M, Maddipatla V, Grebe R, Das M, Lathrop KL, Sahel JA, Zigler JS, Qian J, Ghosh A, Sergeev Y, Handa JT, St Croix CM, Sinha D.
    Autophagy; 2023 Jan 20; 19(1):92-111. PubMed ID: 35473441
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  • 15. The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD.
    Ghosh S, Sharma R, Bammidi S, Koontz V, Nemani M, Yazdankhah M, Kedziora KM, Stolz DB, Wallace CT, Yu-Wei C, Franks J, Bose D, Shang P, Ambrosino HM, Dutton JR, Geng Z, Montford J, Ryu J, Rajasundaram D, Hose S, Sahel JA, Puertollano R, Finkel T, Zigler JS, Sergeev Y, Watkins SC, Goetzman ES, Ferrington DA, Flores-Bellver M, Kaarniranta K, Sodhi A, Bharti K, Handa JT, Sinha D.
    Nat Commun; 2024 Jul 21; 15(1):6150. PubMed ID: 39034314
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  • 16. Inducible RPE-specific GPX4 knockout causes oxidative stress and retinal degeneration with features of age-related macular degeneration.
    Wojciechowski AM, Bell BA, Song Y, Anderson BD, Conomikes A, Petruconis C, Dunaief JL.
    Exp Eye Res; 2024 Oct 21; 247():110028. PubMed ID: 39128667
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  • 18. Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors.
    Brown EE, DeWeerd AJ, Ildefonso CJ, Lewin AS, Ash JD.
    Redox Biol; 2019 Jun 21; 24():101201. PubMed ID: 31039480
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  • 19. Early AMD-like defects in the RPE and retinal degeneration in aged mice with RPE-specific deletion of Atg5 or Atg7.
    Zhang Y, Cross SD, Stanton JB, Marmorstein AD, Le YZ, Marmorstein LY.
    Mol Vis; 2017 Jun 21; 23():228-241. PubMed ID: 28465655
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  • 20. Intense physiological light upregulates vascular endothelial growth factor and enhances choroidal neovascularization via peroxisome proliferator-activated receptor γ coactivator-1α in mice.
    Ueta T, Inoue T, Yuda K, Furukawa T, Yanagi Y, Tamaki Y.
    Arterioscler Thromb Vasc Biol; 2012 Jun 21; 32(6):1366-71. PubMed ID: 22516064
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