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Journal Abstract Search

473 related items for PubMed ID: 30293795

  • 1. Synthesis, in vitro and in vivo biological evaluation, COX-1/2 inhibition and molecular docking study of indole-N-acylhydrazone derivatives.
    Moraes ADTO, Miranda MDS, Jacob ÍTT, Amorim CADC, Moura RO, Silva SÂSD, Soares MBP, Almeida SMV, Souza TRCL, Oliveira JF, Silva TGD, Melo CML, Moreira DRM, Lima MDCA.
    Bioorg Med Chem; 2018 Nov 01; 26(20):5388-5396. PubMed ID: 30293795
    [Abstract] [Full Text] [Related]

  • 2. Synthesis, biological evaluation and docking analysis of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones as potential cyclooxygenase-2 (COX-2) inhibitors.
    Grover J, Kumar V, Sobhia ME, Jachak SM.
    Bioorg Med Chem Lett; 2014 Oct 01; 24(19):4638-4642. PubMed ID: 25219899
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of pyridazinone derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents.
    Ahmed EM, Kassab AE, El-Malah AA, Hassan MSA.
    Eur J Med Chem; 2019 Jun 01; 171():25-37. PubMed ID: 30904755
    [Abstract] [Full Text] [Related]

  • 4. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
    Abdelgawad MA, Labib MB, Abdel-Latif M.
    Bioorg Chem; 2017 Oct 01; 74():212-220. PubMed ID: 28865292
    [Abstract] [Full Text] [Related]

  • 5. Anti-inflammatory drug approach: Synthesis and biological evaluation of novel pyrazolo[3,4-d]pyrimidine compounds.
    Atatreh N, Youssef AM, Ghattas MA, Al Sorkhy M, Alrawashdeh S, Al-Harbi KB, El-Ashmawy IM, Almundarij TI, Abdelghani AA, Abd-El-Aziz AS.
    Bioorg Chem; 2019 May 01; 86():393-400. PubMed ID: 30763886
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis, biological evaluation and docking study of novel indole-2-amide as anti-inflammatory agents with dual inhibition of COX and 5-LOX.
    Huang Y, Zhang B, Li J, Liu H, Zhang Y, Yang Z, Liu W.
    Eur J Med Chem; 2019 Oct 15; 180():41-50. PubMed ID: 31299586
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis and anti-inflammatory assessment of certain substituted 1,2,4-triazoles bearing tetrahydroisoquinoline scaffold as COX 1/2-inhibitors.
    Abo-Elmagd MI, Hassan RM, Aboutabl ME, Amin KM, El-Azzouny AA, Aboul-Enein MN.
    Bioorg Chem; 2024 Sep 15; 150():107577. PubMed ID: 38941697
    [Abstract] [Full Text] [Related]

  • 8. New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
    El-Miligy MMM, Hazzaa AA, El-Messmary H, Nassra RA, El-Hawash SAM.
    Bioorg Chem; 2017 Jun 15; 72():102-115. PubMed ID: 28390993
    [Abstract] [Full Text] [Related]

  • 9. Synthesis, molecular docking, and biological evaluation of some novel hydrazones and pyrazole derivatives as anti-inflammatory agents.
    Mohammed KO, Nissan YM.
    Chem Biol Drug Des; 2014 Oct 15; 84(4):473-88. PubMed ID: 24720475
    [Abstract] [Full Text] [Related]

  • 10. 1,3,4-Trisubstituted pyrazole analogues as promising anti-inflammatory agents.
    Alegaon SG, Alagawadi KR, Garg MK, Dushyant K, Vinod D.
    Bioorg Chem; 2014 Jun 15; 54():51-9. PubMed ID: 24793214
    [Abstract] [Full Text] [Related]

  • 11. Exploring Anti-inflammatory Potential of Thiazolidinone Derivatives of Benzenesulfonamide via Synthesis, Molecular Docking and Biological Evaluation.
    Bari SB, Firake SD.
    Antiinflamm Antiallergy Agents Med Chem; 2016 Jun 15; 15(1):44-53. PubMed ID: 27216235
    [Abstract] [Full Text] [Related]

  • 12. Discovery of new 2-(3-(naphthalen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazole derivatives with potential analgesic and anti-inflammatory activities: In vitro, in vivo and in silico investigations.
    Mohammed ER, Abd-El-Fatah AH, Mohamed AR, Mahrouse MA, Mohammad MA.
    Bioorg Chem; 2024 Jun 15; 147():107372. PubMed ID: 38653152
    [Abstract] [Full Text] [Related]

  • 13. Exploring of novel oxazolones and imidazolones as anti-inflammatory and analgesic candidates with cyclooxygenase inhibitory action.
    Rayan SA, George RF, Mohamed NM, Said MF.
    Future Med Chem; 2024 Jun 15; 16(10):963-981. PubMed ID: 38639393
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study.
    Abdel-Aziz AA, ElTahir KE, Asiri YA.
    Eur J Med Chem; 2011 May 15; 46(5):1648-55. PubMed ID: 21388719
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study.
    El-Sayed MA, Abdel-Aziz NI, Abdel-Aziz AA, El-Azab AS, Asiri YA, Eltahir KE.
    Bioorg Med Chem; 2011 Jun 01; 19(11):3416-24. PubMed ID: 21570309
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, in-vitro, in-vivo anti-inflammatory activities and molecular docking studies of acyl and salicylic acid hydrazide derivatives.
    Munir A, Khushal A, Saeed K, Sadiq A, Ullah R, Ali G, Ashraf Z, Ullah Mughal E, Saeed Jan M, Rashid U, Hussain I, Mumtaz A.
    Bioorg Chem; 2020 Nov 01; 104():104168. PubMed ID: 32947133
    [Abstract] [Full Text] [Related]

  • 17. New pyrazole derivatives: Synthesis, anti-inflammatory activity, cycloxygenase inhibition assay and evaluation of mPGES.
    Hassan GS, Abdel Rahman DE, Abdelmajeed EA, Refaey RH, Alaraby Salem M, Nissan YM.
    Eur J Med Chem; 2019 Jun 01; 171():332-342. PubMed ID: 30928706
    [Abstract] [Full Text] [Related]

  • 18. New pyridazine derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents; design, synthesis and biological evaluation.
    Ahmed EM, Hassan MSA, El-Malah AA, Kassab AE.
    Bioorg Chem; 2020 Jan 01; 95():103497. PubMed ID: 31838289
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and biological evaluation of new nicotinate derivatives as potential anti-inflammatory agents targeting COX-2 enzyme.
    El-Dash Y, Khalil NA, Ahmed EM, Hassan MSA.
    Bioorg Chem; 2021 Feb 01; 107():104610. PubMed ID: 33454504
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and analgesic/anti-inflammatory evaluation of novel diarylthiazole and diarylimidazole derivatives towards selective COX-1 inhibitors with better gastric profile.
    Abdelazeem AH, El-Saadi MT, Safi El-Din AG, Omar HA, El-Moghazy SM.
    Bioorg Med Chem; 2017 Jan 15; 25(2):665-676. PubMed ID: 27916468
    [Abstract] [Full Text] [Related]

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