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245 related items for PubMed ID: 30308208

  • 1. In silico modeling of Plasmodium falciparum chloroquine resistance transporter protein and biochemical studies suggest its key contribution to chloroquine resistance.
    Antony HA, Topno NS, Gummadi SN, Siva Sankar D, Krishna R, Parija SC.
    Acta Trop; 2019 Jan; 189():84-93. PubMed ID: 30308208
    [Abstract] [Full Text] [Related]

  • 2. A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs.
    Jida M, Sanchez CP, Urgin K, Ehrhardt K, Mounien S, Geyer A, Elhabiri M, Lanzer M, Davioud-Charvet E.
    ACS Infect Dis; 2017 Feb 10; 3(2):119-131. PubMed ID: 28183182
    [Abstract] [Full Text] [Related]

  • 3. Functional characteristics of the malaria parasite's "chloroquine resistance transporter": implications for chemotherapy.
    Summers RL, Martin RE.
    Virulence; 2010 Feb 10; 1(4):304-8. PubMed ID: 21178460
    [Abstract] [Full Text] [Related]

  • 4. Is PfCRT a channel or a carrier? Two competing models explaining chloroquine resistance in Plasmodium falciparum.
    Sanchez CP, Stein WD, Lanzer M.
    Trends Parasitol; 2007 Jul 10; 23(7):332-9. PubMed ID: 17493873
    [Abstract] [Full Text] [Related]

  • 5. Chloroquine transport via the malaria parasite's chloroquine resistance transporter.
    Martin RE, Marchetti RV, Cowan AI, Howitt SM, Bröer S, Kirk K.
    Science; 2009 Sep 25; 325(5948):1680-2. PubMed ID: 19779197
    [Abstract] [Full Text] [Related]

  • 6. Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance Transporter.
    Richards SN, Nash MN, Baker ES, Webster MW, Lehane AM, Shafik SH, Martin RE.
    PLoS Pathog; 2016 Jul 25; 12(7):e1005725. PubMed ID: 27441371
    [Abstract] [Full Text] [Related]

  • 7. Combinatorial Genetic Modeling of pfcrt-Mediated Drug Resistance Evolution in Plasmodium falciparum.
    Gabryszewski SJ, Modchang C, Musset L, Chookajorn T, Fidock DA.
    Mol Biol Evol; 2016 Jun 25; 33(6):1554-70. PubMed ID: 26908582
    [Abstract] [Full Text] [Related]

  • 8. Prevalence of crt and mdr-1 mutations in Plasmodium falciparum isolates from Grande Comore island after withdrawal of chloroquine.
    Huang B, Wang Q, Deng C, Wang J, Yang T, Huang S, Su XZ, Liu Y, Pan L, Li G, Li D, Zhang H, Bacar A, Abdallah KS, Attoumane R, Mliva AM, Zheng S, Xu Q, Lu F, Guan Y, Song J.
    Malar J; 2016 Aug 15; 15(1):414. PubMed ID: 27527604
    [Abstract] [Full Text] [Related]

  • 9. Survey of chloroquine-resistant mutations in the Plasmodium falciparum pfcrt and pfmdr-1 genes in Hadhramout, Yemen.
    Bamaga OA, Mahdy MA, Lim YA.
    Acta Trop; 2015 Sep 15; 149():59-63. PubMed ID: 26001972
    [Abstract] [Full Text] [Related]

  • 10. Structure and drug resistance of the Plasmodium falciparum transporter PfCRT.
    Kim J, Tan YZ, Wicht KJ, Erramilli SK, Dhingra SK, Okombo J, Vendome J, Hagenah LM, Giacometti SI, Warren AL, Nosol K, Roepe PD, Potter CS, Carragher B, Kossiakoff AA, Quick M, Fidock DA, Mancia F.
    Nature; 2019 Dec 15; 576(7786):315-320. PubMed ID: 31776516
    [Abstract] [Full Text] [Related]

  • 11. Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum.
    Valderramos SG, Valderramos JC, Musset L, Purcell LA, Mercereau-Puijalon O, Legrand E, Fidock DA.
    PLoS Pathog; 2010 May 13; 6(5):e1000887. PubMed ID: 20485514
    [Abstract] [Full Text] [Related]

  • 12. Structural and evolutionary analyses of the Plasmodium falciparum chloroquine resistance transporter.
    Coppée R, Sabbagh A, Clain J.
    Sci Rep; 2020 Mar 16; 10(1):4842. PubMed ID: 32179795
    [Abstract] [Full Text] [Related]

  • 13. Functional Comparison of 45 Naturally Occurring Isoforms of the Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT).
    Callaghan PS, Hassett MR, Roepe PD.
    Biochemistry; 2015 Aug 18; 54(32):5083-94. PubMed ID: 26208441
    [Abstract] [Full Text] [Related]

  • 14. Return of chloroquine sensitivity to Africa? Surveillance of African Plasmodium falciparum chloroquine resistance through malaria imported to China.
    Lu F, Zhang M, Culleton RL, Xu S, Tang J, Zhou H, Zhu G, Gu Y, Zhang C, Liu Y, Wang W, Cao Y, Li J, He X, Cao J, Gao Q.
    Parasit Vectors; 2017 Jul 26; 10(1):355. PubMed ID: 28747223
    [Abstract] [Full Text] [Related]

  • 15. Changes in genotypes of Plasmodium falciparum human malaria parasite following withdrawal of chloroquine in Tiwi, Kenya.
    Mang'era CM, Mbai FN, Omedo IA, Mireji PO, Omar SA.
    Acta Trop; 2012 Sep 26; 123(3):202-7. PubMed ID: 22641431
    [Abstract] [Full Text] [Related]

  • 16. The return of chloroquine-sensitive Plasmodium falciparum parasites in Jazan region, southwestern Saudi Arabia over a decade after the adoption of artemisinin-based combination therapy: analysis of genetic mutations in the pfcrt gene.
    Madkhali AM, Abdulhaq AA, Atroosh WM, Ghzwani AH, Zain KA, Ghailan KY, Hamali HA, Mobarki AA, Eisa ZM, Lau YL, Al-Mekhlafi HM.
    Parasitol Res; 2021 Nov 26; 120(11):3771-3781. PubMed ID: 34561749
    [Abstract] [Full Text] [Related]

  • 17. Large-scale survey for novel genotypes of Plasmodium falciparum chloroquine-resistance gene pfcrt.
    Takahashi N, Tanabe K, Tsukahara T, Dzodzomenyo M, Dysoley L, Khamlome B, Sattabongkot J, Nakamura M, Sakurai M, Kobayashi J, Kaneko A, Endo H, Hombhanje F, Tsuboi T, Mita T.
    Malar J; 2012 Mar 28; 11():92. PubMed ID: 22453078
    [Abstract] [Full Text] [Related]

  • 18. Therapeutic efficacy of chloroquine and sequence variation in pfcrt gene among patients with falciparum malaria in central India.
    Bharti PK, Alam MT, Boxer R, Shukla MM, Gautam SP, Sharma YD, Singh N.
    Trop Med Int Health; 2010 Jan 28; 15(1):33-40. PubMed ID: 19912592
    [Abstract] [Full Text] [Related]

  • 19. A 2-amino quinoline, 5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid, interacts with PfMDR1 and inhibits its drug transport in Plasmodium falciparum.
    Edaye S, Reiling SJ, Leimanis ML, Wunderlich J, Rohrbach P, Georges E.
    Mol Biochem Parasitol; 2014 Jun 28; 195(1):34-42. PubMed ID: 24914817
    [Abstract] [Full Text] [Related]

  • 20. Glutathione transport: a new role for PfCRT in chloroquine resistance.
    Patzewitz EM, Salcedo-Sora JE, Wong EH, Sethia S, Stocks PA, Maughan SC, Murray JA, Krishna S, Bray PG, Ward SA, Müller S.
    Antioxid Redox Signal; 2013 Sep 01; 19(7):683-95. PubMed ID: 23256874
    [Abstract] [Full Text] [Related]

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