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Journal Abstract Search

424 related items for PubMed ID: 30333365

  • 1. Suppression of free fatty acid receptor 1 expression in pancreatic β-cells in obese type 2 diabetic db/db mice: a potential role of pancreatic and duodenal homeobox factor 1.
    Kohara K, Obata A, Kimura T, Shimoda M, Moriuchi S, Okauchi S, Hirukawa H, Mune T, Kaku K, Kaneto H.
    Endocr J; 2019 Jan 28; 66(1):43-50. PubMed ID: 30333365
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  • 2. GPR120 protects lipotoxicity-induced pancreatic β-cell dysfunction through regulation of PDX1 expression and inhibition of islet inflammation.
    Wang Y, Xie T, Zhang D, Leung PS.
    Clin Sci (Lond); 2019 Jan 15; 133(1):101-116. PubMed ID: 30523046
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  • 4. Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats.
    Gowda N, Dandu A, Singh J, Biswas S, Raghav V, Lakshmi MN, Shilpa PC, Sunil V, Reddy A, Sadasivuni M, Aparna K, Verma MK, Moolemath Y, Anup MO, Venkataranganna MV, Somesh BP, Jagannath MR.
    BMC Pharmacol Toxicol; 2013 May 21; 14():28. PubMed ID: 23692921
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  • 7. SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice.
    Iguchi H, Ikeda Y, Okamura M, Tanaka T, Urashima Y, Ohguchi H, Takayasu S, Kojima N, Iwasaki S, Ohashi R, Jiang S, Hasegawa G, Ioka RX, Magoori K, Sumi K, Maejima T, Uchida A, Naito M, Osborne TF, Yanagisawa M, Yamamoto TT, Kodama T, Sakai J.
    J Biol Chem; 2005 Nov 11; 280(45):37669-80. PubMed ID: 16148004
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  • 9. RNA m6A reader IMP2/IGF2BP2 promotes pancreatic β-cell proliferation and insulin secretion by enhancing PDX1 expression.
    Regué L, Zhao L, Ji F, Wang H, Avruch J, Dai N.
    Mol Metab; 2021 Jun 11; 48():101209. PubMed ID: 33705986
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  • 10. Dracorhodin perchlorate protects pancreatic β-cells against glucotoxicity- or lipotoxicity-induced dysfunction and apoptosis in vitro and in vivo.
    Liu L, Liang C, Mei P, Zhu H, Hou M, Yu C, Song Z, Bao Y, Huang Y, Yi J, Wang S, Wu Y, Zheng L, Sun Y, Wang G, Huo M, Yang S, Sun L, Li Y.
    FEBS J; 2019 Sep 11; 286(18):3718-3736. PubMed ID: 31349381
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  • 11. Acarbose ameliorates spontaneous type‑2 diabetes in db/db mice by inhibiting PDX‑1 methylation.
    Zhou D, Chen L, Mou X.
    Mol Med Rep; 2021 Jan 11; 23(1):. PubMed ID: 33236139
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  • 12. Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance.
    Sabrautzki S, Kaiser G, Przemeck GKH, Gerst F, Lorza-Gil E, Panse M, Sartorius T, Hoene M, Marschall S, Häring HU, Hrabě de Angelis M, Ullrich S.
    Mol Metab; 2017 Oct 11; 6(10):1304-1312. PubMed ID: 29031729
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  • 13. Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.
    Wang X, Sterr M, Burtscher I, Chen S, Hieronimus A, Machicao F, Staiger H, Häring HU, Lederer G, Meitinger T, Cernilogar FM, Schotta G, Irmler M, Beckers J, Hrabě de Angelis M, Ray M, Wright CVE, Bakhti M, Lickert H.
    Mol Metab; 2018 Mar 11; 9():57-68. PubMed ID: 29396371
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  • 14. Self-Transducible Bimodal PDX1-FOXP3 Protein Lifts Insulin Secretion and Curbs Autoimmunity, Boosting Tregs in Type 1 Diabetic Mice.
    Amatya C, Radichev IA, Ellefson J, Williams M, Savinov AY.
    Mol Ther; 2018 Jan 03; 26(1):184-198. PubMed ID: 28988715
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  • 16. TAK-875, a GPR40/FFAR1 agonist, in combination with metformin prevents progression of diabetes and β-cell dysfunction in Zucker diabetic fatty rats.
    Ito R, Tsujihata Y, Matsuda-Nagasumi K, Mori I, Negoro N, Takeuchi K.
    Br J Pharmacol; 2013 Oct 03; 170(3):568-80. PubMed ID: 23848179
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  • 17. Forkhead box O1/pancreatic and duodenal homeobox 1 intracellular translocation is regulated by c-Jun N-terminal kinase and involved in prostaglandin E2-induced pancreatic beta-cell dysfunction.
    Meng Z, Lv J, Luo Y, Lin Y, Zhu Y, Nie J, Yang T, Sun Y, Han X.
    Endocrinology; 2009 Dec 03; 150(12):5284-93. PubMed ID: 19837872
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  • 18. Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells.
    Marafie SK, Al-Shawaf EM, Abubaker J, Arefanian H.
    Biol Res; 2019 Aug 19; 52(1):44. PubMed ID: 31426858
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  • 19. Lack of GPR40/FFAR1 does not induce diabetes even under insulin resistance condition.
    Matsuda-Nagasumi K, Takami-Esaki R, Iwachidow K, Yasuhara Y, Tanaka H, Ogi K, Nakata M, Yano T, Hinuma S, Taketomi S, Odaka H, Kaisho Y.
    Diabetes Obes Metab; 2013 Jun 19; 15(6):538-45. PubMed ID: 23331570
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  • 20. Saturated fatty acids entrap PDX1 in stress granules and impede islet beta cell function.
    Zhang M, Yang C, Zhu M, Qian L, Luo Y, Cheng H, Geng R, Xu X, Qian C, Liu Y.
    Diabetologia; 2021 May 19; 64(5):1144-1157. PubMed ID: 33569632
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