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187 related items for PubMed ID: 30354045

  • 1. De Novo Design and Implementation of a Tandem Acyl Carrier Protein Domain in a Type I Modular Polyketide Synthase.
    Wang Z, Bagde SR, Zavala G, Matsui T, Chen X, Kim CY.
    ACS Chem Biol; 2018 Nov 16; 13(11):3072-3077. PubMed ID: 30354045
    [Abstract] [Full Text] [Related]

  • 2. Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase.
    Chen AY, Schnarr NA, Kim CY, Cane DE, Khosla C.
    J Am Chem Soc; 2006 Mar 08; 128(9):3067-74. PubMed ID: 16506788
    [Abstract] [Full Text] [Related]

  • 3. Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases.
    Yuzawa S, Kapur S, Cane DE, Khosla C.
    Biochemistry; 2012 May 08; 51(18):3708-10. PubMed ID: 22509729
    [Abstract] [Full Text] [Related]

  • 4. Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase.
    Kapur S, Chen AY, Cane DE, Khosla C.
    Proc Natl Acad Sci U S A; 2010 Dec 21; 107(51):22066-71. PubMed ID: 21127271
    [Abstract] [Full Text] [Related]

  • 5. Enhancing the modularity of the modular polyketide synthases: transacylation in modular polyketide synthases catalyzed by malonyl-CoA:ACP transacylase.
    Kumar P, Koppisch AT, Cane DE, Khosla C.
    J Am Chem Soc; 2003 Nov 26; 125(47):14307-12. PubMed ID: 14624579
    [Abstract] [Full Text] [Related]

  • 6. Reprogramming a module of the 6-deoxyerythronolide B synthase for iterative chain elongation.
    Kapur S, Lowry B, Yuzawa S, Kenthirapalan S, Chen AY, Cane DE, Khosla C.
    Proc Natl Acad Sci U S A; 2012 Mar 13; 109(11):4110-5. PubMed ID: 22371562
    [Abstract] [Full Text] [Related]

  • 7. Insights into modular polyketide synthase loops aided by repetitive sequences.
    Hirsch M, Kumru K, Desai RR, Fitzgerald BJ, Miyazawa T, Ray KA, Saif N, Spears S, Keatinge-Clay AT.
    Proteins; 2021 Sep 13; 89(9):1099-1110. PubMed ID: 33843112
    [Abstract] [Full Text] [Related]

  • 8. Structure, function and dynamics in acyl carrier proteins.
    Farmer R, Thomas CM, Winn PJ.
    PLoS One; 2019 Sep 13; 14(7):e0219435. PubMed ID: 31291335
    [Abstract] [Full Text] [Related]

  • 9. Tandem acyl carrier protein domains in polyunsaturated fatty acid synthases.
    Jiang H, Rajski SR, Shen B.
    Methods Enzymol; 2009 Sep 13; 459():79-96. PubMed ID: 19362636
    [Abstract] [Full Text] [Related]

  • 10. Probing the interactions of an acyl carrier protein domain from the 6-deoxyerythronolide B synthase.
    Charkoudian LK, Liu CW, Capone S, Kapur S, Cane DE, Togni A, Seebach D, Khosla C.
    Protein Sci; 2011 Jul 13; 20(7):1244-55. PubMed ID: 21563224
    [Abstract] [Full Text] [Related]

  • 11. Exploring Fungal Polyketide C-Methylation through Combinatorial Domain Swaps.
    Storm PA, Pal P, Huitt-Roehl CR, Townsend CA.
    ACS Chem Biol; 2018 Nov 16; 13(11):3043-3048. PubMed ID: 30350943
    [Abstract] [Full Text] [Related]

  • 12. Biochemical characterization of the minimal polyketide synthase domains in the lovastatin nonaketide synthase LovB.
    Ma SM, Tang Y.
    FEBS J; 2007 Jun 16; 274(11):2854-64. PubMed ID: 17466016
    [Abstract] [Full Text] [Related]

  • 13. Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase.
    Kim CY, Alekseyev VY, Chen AY, Tang Y, Cane DE, Khosla C.
    Biochemistry; 2004 Nov 09; 43(44):13892-8. PubMed ID: 15518537
    [Abstract] [Full Text] [Related]

  • 14. Protein-protein recognition between acyltransferases and acyl carrier proteins in multimodular polyketide synthases.
    Wong FT, Chen AY, Cane DE, Khosla C.
    Biochemistry; 2010 Jan 12; 49(1):95-102. PubMed ID: 19921859
    [Abstract] [Full Text] [Related]

  • 15. Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate.
    Maloney FP, Gerwick L, Gerwick WH, Sherman DH, Smith JL.
    Proc Natl Acad Sci U S A; 2016 Sep 13; 113(37):10316-21. PubMed ID: 27573844
    [Abstract] [Full Text] [Related]

  • 16. Polyketide Synthase Modules Redefined.
    Keatinge-Clay AT.
    Angew Chem Int Ed Engl; 2017 Apr 18; 56(17):4658-4660. PubMed ID: 28322495
    [Abstract] [Full Text] [Related]

  • 17. Structural basis for selectivity in a highly reducing type II polyketide synthase.
    Du D, Katsuyama Y, Horiuchi M, Fushinobu S, Chen A, Davis TD, Burkart MD, Ohnishi Y.
    Nat Chem Biol; 2020 Jul 18; 16(7):776-782. PubMed ID: 32367018
    [Abstract] [Full Text] [Related]

  • 18. Engineered Chimeras Unveil Swappable Modular Features of Fatty Acid and Polyketide Synthase Acyl Carrier Proteins.
    Cho YI, Armstrong CL, Sulpizio A, Acheampong KK, Banks KN, Bardhan O, Churchill SJ, Connolly-Sporing AE, Crawford CEW, Cruz Parrilla PL, Curtis SM, De La Ossa LM, Epstein SC, Farrehi CJ, Hamrick GS, Hillegas WJ, Kang A, Laxton OC, Ling J, Matsumura SM, Merino VM, Mukhtar SH, Shah NJ, Londergan CH, Daly CA, Kokona B, Charkoudian LK.
    Biochemistry; 2022 Feb 15; 61(4):217-227. PubMed ID: 35073057
    [Abstract] [Full Text] [Related]

  • 19. Offloading Role of a Discrete Thioesterase in Type II Polyketide Biosynthesis.
    Hua K, Liu X, Zhao Y, Gao Y, Pan L, Zhang H, Deng Z, Jiang M.
    mBio; 2020 Sep 15; 11(5):. PubMed ID: 32934080
    [Abstract] [Full Text] [Related]

  • 20. Sticky swinging arm dynamics: studies of an acyl carrier protein domain from the mycolactone polyketide synthase.
    Vance S, Tkachenko O, Thomas B, Bassuni M, Hong H, Nietlispach D, Broadhurst W.
    Biochem J; 2016 Apr 15; 473(8):1097-110. PubMed ID: 26920023
    [Abstract] [Full Text] [Related]

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