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Journal Abstract Search

249 related items for PubMed ID: 30368131

  • 1. Optimization of a fragment linking hit toward Dengue and Zika virus NS5 methyltransferases inhibitors.
    Hernandez J, Hoffer L, Coutard B, Querat G, Roche P, Morelli X, Decroly E, Barral K.
    Eur J Med Chem; 2019 Jan 01; 161():323-333. PubMed ID: 30368131
    [Abstract] [Full Text] [Related]

  • 2. Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design.
    Benmansour F, Trist I, Coutard B, Decroly E, Querat G, Brancale A, Barral K.
    Eur J Med Chem; 2017 Jan 05; 125():865-880. PubMed ID: 27750202
    [Abstract] [Full Text] [Related]

  • 3. Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives.
    Coutard B, Barral K, Lichière J, Selisko B, Martin B, Aouadi W, Lombardia MO, Debart F, Vasseur JJ, Guillemot JC, Canard B, Decroly E.
    J Virol; 2017 Mar 01; 91(5):. PubMed ID: 28031359
    [Abstract] [Full Text] [Related]

  • 4. Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitors.
    Nascimento IJDS, Santos-Júnior PFDS, Aquino TM, Araújo-Júnior JX, Silva-Júnior EFD.
    Eur J Med Chem; 2021 Nov 15; 224():113698. PubMed ID: 34274831
    [Abstract] [Full Text] [Related]

  • 5. Design, Synthesis and Discovery of N,N'-Carbazoyl-aryl-urea Inhibitors of Zika NS5 Methyltransferase and Virus Replication.
    Spizzichino S, Mattedi G, Lauder K, Valle C, Aouadi W, Canard B, Decroly E, Kaptein SJF, Neyts J, Graham C, Sule Z, Barlow DJ, Silvestri R, Castagnolo D.
    ChemMedChem; 2020 Feb 17; 15(4):385-390. PubMed ID: 31805205
    [Abstract] [Full Text] [Related]

  • 6. Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase.
    Cannalire R, Tarantino D, Astolfi A, Barreca ML, Sabatini S, Massari S, Tabarrini O, Milani M, Querat G, Mastrangelo E, Manfroni G, Cecchetti V.
    Eur J Med Chem; 2018 Jan 01; 143():1667-1676. PubMed ID: 29137867
    [Abstract] [Full Text] [Related]

  • 7. Assessment of Dengue virus helicase and methyltransferase as targets for fragment-based drug discovery.
    Coutard B, Decroly E, Li C, Sharff A, Lescar J, Bricogne G, Barral K.
    Antiviral Res; 2014 Jun 01; 106():61-70. PubMed ID: 24704437
    [Abstract] [Full Text] [Related]

  • 8. Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase.
    Gharbi-Ayachi A, Santhanakrishnan S, Wong YH, Chan KWK, Tan ST, Bates RW, Vasudevan SG, El Sahili A, Lescar J.
    J Virol; 2020 Oct 14; 94(21):. PubMed ID: 32796069
    [Abstract] [Full Text] [Related]

  • 9. Structure-based and ligand-based virtual screening of novel methyltransferase inhibitors of the dengue virus.
    Lim SV, Rahman MB, Tejo BA.
    BMC Bioinformatics; 2011 Oct 14; 12 Suppl 13(Suppl 13):S24. PubMed ID: 22373153
    [Abstract] [Full Text] [Related]

  • 10. Discovery of Potent Non-nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from Fragment Screening and Structure-Guided Design.
    Lim SP, Noble CG, Nilar S, Shi PY, Yokokawa F.
    Adv Exp Med Biol; 2018 Oct 14; 1062():187-198. PubMed ID: 29845534
    [Abstract] [Full Text] [Related]

  • 11. NS5 from Dengue Virus Serotype 2 Can Adopt a Conformation Analogous to That of Its Zika Virus and Japanese Encephalitis Virus Homologues.
    El Sahili A, Soh TS, Schiltz J, Gharbi-Ayachi A, Seh CC, Shi PY, Lim SP, Lescar J.
    J Virol; 2019 Dec 12; 94(1):. PubMed ID: 31597763
    [Abstract] [Full Text] [Related]

  • 12. Development of specific dengue virus 2'-O- and N7-methyltransferase assays for antiviral drug screening.
    Barral K, Sallamand C, Petzold C, Coutard B, Collet A, Thillier Y, Zimmermann J, Vasseur JJ, Canard B, Rohayem J, Debart F, Decroly E.
    Antiviral Res; 2013 Sep 12; 99(3):292-300. PubMed ID: 23769894
    [Abstract] [Full Text] [Related]

  • 13. Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling.
    Lim SP, Noble CG, Seh CC, Soh TS, El Sahili A, Chan GK, Lescar J, Arora R, Benson T, Nilar S, Manjunatha U, Wan KF, Dong H, Xie X, Shi PY, Yokokawa F.
    PLoS Pathog; 2016 Aug 12; 12(8):e1005737. PubMed ID: 27500641
    [Abstract] [Full Text] [Related]

  • 14. Structural Insight into NS5 of Zika Virus Leading to the Discovery of MTase Inhibitors.
    Stephen P, Baz M, Boivin G, Lin SX.
    J Am Chem Soc; 2016 Dec 21; 138(50):16212-16215. PubMed ID: 27998085
    [Abstract] [Full Text] [Related]

  • 15. In silico designing and screening of lead compounds to NS5-methyltransferase of dengue viruses.
    Sivakumar D, Sivaraman T.
    Med Chem; 2011 Nov 21; 7(6):655-62. PubMed ID: 22313305
    [Abstract] [Full Text] [Related]

  • 16. Discovery of Novel Druggable Sites on Zika Virus NS3 Helicase Using X-ray Crystallography-Based Fragment Screening.
    Munawar A, Beelen S, Munawar A, Lescrinier E, Strelkov SV.
    Int J Mol Sci; 2018 Nov 20; 19(11):. PubMed ID: 30463319
    [Abstract] [Full Text] [Related]

  • 17. Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor design.
    Zhang C, Feng T, Cheng J, Li Y, Yin X, Zeng W, Jin X, Li Y, Guo F, Jin T.
    Biochem Biophys Res Commun; 2017 Oct 28; 492(4):624-630. PubMed ID: 27866982
    [Abstract] [Full Text] [Related]

  • 18. Antiviral Activity of Compound L3 against Dengue and Zika Viruses In Vitro and In Vivo.
    Chuang FK, Liao CL, Hu MK, Chiu YL, Lee AR, Huang SM, Chiu YL, Tsai PL, Su BC, Chang TH, Lin CC, Shih CC, Yen LC.
    Int J Mol Sci; 2020 Jun 05; 21(11):. PubMed ID: 32517029
    [Abstract] [Full Text] [Related]

  • 19. Small-Molecule Inhibitor of Flaviviral NS3-NS5 Interaction with Broad-Spectrum Activity and Efficacy In Vivo.
    Celegato M, Sturlese M, Vasconcelos Costa V, Trevisan M, Lallo Dias AS, Souza Passos IB, Queiroz-Junior CM, Messa L, Favaro A, Moro S, Teixeira MM, Loregian A, Mercorelli B.
    mBio; 2023 Feb 28; 14(1):e0309722. PubMed ID: 36622141
    [Abstract] [Full Text] [Related]

  • 20. The crystal structure of Zika virus NS5 reveals conserved drug targets.
    Duan W, Song H, Wang H, Chai Y, Su C, Qi J, Shi Y, Gao GF.
    EMBO J; 2017 Apr 03; 36(7):919-933. PubMed ID: 28254839
    [Abstract] [Full Text] [Related]

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