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Journal Abstract Search

122 related items for PubMed ID: 30380557

  • 1. A Novel Inhibitor of Homodimerization Targeting MyD88 Ameliorates Renal Interstitial Fibrosis by Counteracting TGF-β1-Induced EMT in Vivo and in Vitro.
    Liu JH, He L, Zou ZM, Ding ZC, Zhang X, Wang H, Zhou P, Xie L, Xing S, Yi CZ.
    Kidney Blood Press Res; 2018; 43(5):1677-1687. PubMed ID: 30380557
    [Abstract] [Full Text] [Related]

  • 2. Pharmacological inhibition of MyD88 homodimerization counteracts renal ischemia reperfusion-induced progressive renal injury in vivo and in vitro.
    Zhang LM, Liu JH, Xue CB, Li MQ, Xing S, Zhang X, He WT, Jiang FC, Lu X, Zhou P.
    Sci Rep; 2016 Jun 01; 6():26954. PubMed ID: 27246399
    [Abstract] [Full Text] [Related]

  • 3. Targeting of MyD88 Homodimerization by Novel Synthetic Inhibitor TJ-M2010-5 in Preventing Colitis-Associated Colorectal Cancer.
    Xie L, Jiang FC, Zhang LM, He WT, Liu JH, Li MQ, Zhang X, Xing S, Guo H, Zhou P.
    J Natl Cancer Inst; 2016 Apr 01; 108(4):. PubMed ID: 26712311
    [Abstract] [Full Text] [Related]

  • 4. TJ-M2010-5, A self-developed MyD88 inhibitor, attenuates liver fibrosis by inhibiting the NF-κB pathway.
    Xie Y, Du D, Zhang L, Yang Y, Zou Z, Li Z, Zhou L, Shang R, Zhou P.
    Chem Biol Interact; 2022 Feb 25; 354():109839. PubMed ID: 35101388
    [Abstract] [Full Text] [Related]

  • 5. The MyD88 inhibitor TJ-M2010-2 suppresses proliferation, migration and invasion of breast cancer cells by regulating MyD88/GSK-3β and MyD88/NF-κB signalling pathways.
    Liu JH, Chen C, Li ZY, Zou ZM, Gao DC, Zhang X, Kuang XW, Sun ZH, Zheng WJ, Zhou P, Sun SR.
    Exp Cell Res; 2020 Sep 15; 394(2):112157. PubMed ID: 32610185
    [Abstract] [Full Text] [Related]

  • 6. Total flavonoids from Smilax glabra Roxb blocks epithelial-mesenchymal transition and inhibits renal interstitial fibrosis by targeting miR-21/PTEN signaling.
    Luo Q, Cai Z, Tu J, Ling Y, Wang D, Cai Y.
    J Cell Biochem; 2019 Mar 15; 120(3):3861-3873. PubMed ID: 30304552
    [Abstract] [Full Text] [Related]

  • 7. Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways.
    Li R, Guo Y, Zhang Y, Zhang X, Zhu L, Yan T.
    Int J Mol Sci; 2019 Mar 04; 20(5):. PubMed ID: 30836660
    [Abstract] [Full Text] [Related]

  • 8. Ursolic acid inhibits epithelial-mesenchymal transition in vitro and in vivo.
    Xu CG, Zhu XL, Wang W, Zhou XJ.
    Pharm Biol; 2019 Dec 04; 57(1):169-175. PubMed ID: 30905239
    [Abstract] [Full Text] [Related]

  • 9. Short-term use of MyD88 inhibitor TJ-M2010-5 prevents d-galactosamine/lipopolysaccharide-induced acute liver injury in mice.
    Ding Z, Du D, Yang Y, Yang M, Miao Y, Zou Z, Zhang X, Li Z, Zhang X, Zhang L, Wang X, Zhao Y, Jiang J, Jiang F, Zhou P.
    Int Immunopharmacol; 2019 Feb 04; 67():356-365. PubMed ID: 30583234
    [Abstract] [Full Text] [Related]

  • 10. Short-term Pharmacological Inhibition of MyD88 Homodimerization by a Novel Inhibitor Promotes Robust Allograft Tolerance in Mouse Cardiac and Skin Transplantation.
    Li C, Zhang LM, Zhang X, Huang X, Liu Y, Li MQ, Xing S, Yang T, Xie L, Jiang FC, Jiang HY, He WT, Zhou P.
    Transplantation; 2017 Feb 04; 101(2):284-293. PubMed ID: 27607533
    [Abstract] [Full Text] [Related]

  • 11. Beyond knockout: A novel homodimerization-targeting MyD88 inhibitor prevents and cures type 1 diabetes in NOD mice.
    Zhang X, Xing S, Li M, Zhang L, Xie L, He W, Liu J, Chang S, Jiang F, Zhou P.
    Metabolism; 2016 Sep 04; 65(9):1267-77. PubMed ID: 27506734
    [Abstract] [Full Text] [Related]

  • 12. miR-21 overexpression enhances TGF-β1-induced epithelial-to-mesenchymal transition by target smad7 and aggravates renal damage in diabetic nephropathy.
    Wang JY, Gao YB, Zhang N, Zou DW, Wang P, Zhu ZY, Li JY, Zhou SN, Wang SC, Wang YY, Yang JK.
    Mol Cell Endocrinol; 2014 Jul 05; 392(1-2):163-72. PubMed ID: 24887517
    [Abstract] [Full Text] [Related]

  • 13. Salvianolic acid B prevents epithelial-to-mesenchymal transition through the TGF-beta1 signal transduction pathway in vivo and in vitro.
    Wang QL, Tao YY, Yuan JL, Shen L, Liu CH.
    BMC Cell Biol; 2010 May 05; 11():31. PubMed ID: 20441599
    [Abstract] [Full Text] [Related]

  • 14. Modulating the conformation of the TIR domain by a neoteric MyD88 inhibitor leads to the separation of GVHD from GVT.
    Xing S, Zhang X, Huang X, Xie L, Jiang F, Zhou P.
    Leuk Lymphoma; 2019 Jun 05; 60(6):1528-1539. PubMed ID: 30501537
    [Abstract] [Full Text] [Related]

  • 15. Liuwei Dihuang Decoction Drug-containing Serum Attenuates Transforming Growth Factor-β1-induced Epithelial-mesenchymal Transition in HK-2 Cells by Inhibiting NF-κB/Snail Signaling Pathway.
    Pan J, Jiang Y, Huang Y, Zhang H, Wang X, Luo C, Wang H, Tang M, Pei G, Tang Q.
    Curr Pharm Biotechnol; 2023 Jun 05; 24(12):1589-1602. PubMed ID: 36852808
    [Abstract] [Full Text] [Related]

  • 16. Alpha1-Antitrypsin Attenuates Renal Fibrosis by Inhibiting TGF-β1-Induced Epithelial Mesenchymal Transition.
    Cho JH, Ryu HM, Oh EJ, Yook JM, Ahn JS, Jung HY, Choi JY, Park SH, Kim YL, Kwak IS, Kim CD.
    PLoS One; 2016 Jun 05; 11(9):e0162186. PubMed ID: 27607429
    [Abstract] [Full Text] [Related]

  • 17. TJ-M2010-5 Attenuates Severe Myocardial Ischemia/Reperfusion Injury in Heart Transplantation by Inhibiting MyD88 Homodimerization In Vivo.
    Yang H, Zhou P, Li Q, Zhou X, Li J, Wang J, Wang J, Zhao Y, Yang B, Zhang B, Dai C, Zou Z, Yang Y, Chen Z.
    J Cardiovasc Transl Res; 2022 Dec 05; 15(6):1366-1376. PubMed ID: 35411418
    [Abstract] [Full Text] [Related]

  • 18. The regulatory peptide apelin: a novel inhibitor of renal interstitial fibrosis.
    Wang LY, Diao ZL, Zhang DL, Zheng JF, Zhang QD, Ding JX, Liu WH.
    Amino Acids; 2014 Dec 05; 46(12):2693-704. PubMed ID: 25164121
    [Abstract] [Full Text] [Related]

  • 19. Pirfenidone suppresses MAPK signalling pathway to reverse epithelial-mesenchymal transition and renal fibrosis.
    Li Z, Liu X, Wang B, Nie Y, Wen J, Wang Q, Gu C.
    Nephrology (Carlton); 2017 Aug 05; 22(8):589-597. PubMed ID: 27245114
    [Abstract] [Full Text] [Related]

  • 20. BMP-2 suppresses renal interstitial fibrosis by regulating epithelial-mesenchymal transition.
    Yang YL, Ju HZ, Liu SF, Lee TC, Shih YW, Chuang LY, Guh JY, Yang YY, Liao TN, Hung TJ, Hung MY.
    J Cell Biochem; 2011 Sep 05; 112(9):2558-65. PubMed ID: 21590708
    [Abstract] [Full Text] [Related]

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