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Journal Abstract Search


208 related items for PubMed ID: 30412832

  • 1. Novel glucopyranoside C2-derived 1,2,3-triazoles displaying selective inhibition of O-GlcNAcase (OGA).
    Igual MO, Nunes PSG, da Costa RM, Mantoani SP, Tostes RC, Carvalho I.
    Carbohydr Res; 2019 Jan 01; 471():43-55. PubMed ID: 30412832
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  • 5. GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation.
    Dorfmueller HC, Borodkin VS, Schimpl M, van Aalten DM.
    Biochem J; 2009 May 13; 420(2):221-7. PubMed ID: 19275764
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  • 7. Diazaspirononane Nonsaccharide Inhibitors of O-GlcNAcase (OGA) for the Treatment of Neurodegenerative Disorders.
    Martínez-Viturro CM, Trabanco AA, Royes J, Fernández E, Tresadern G, Vega JA, Del Cerro A, Delgado F, García Molina A, Tovar F, Shaffer P, Ebneth A, Bretteville A, Mertens L, Somers M, Alonso JM, Bartolomé-Nebreda JM.
    J Med Chem; 2020 Nov 25; 63(22):14017-14044. PubMed ID: 33197187
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  • 9. O-GlcNAcase overexpression reverses coronary endothelial cell dysfunction in type 1 diabetic mice.
    Makino A, Dai A, Han Y, Youssef KD, Wang W, Donthamsetty R, Scott BT, Wang H, Dillmann WH.
    Am J Physiol Cell Physiol; 2015 Nov 01; 309(9):C593-9. PubMed ID: 26269457
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  • 10. Defining the structural origin of the substrate sequence independence of O-GlcNAcase using a combination of molecular docking and dynamics simulation.
    Martin JC, Fadda E, Ito K, Woods RJ.
    Glycobiology; 2014 Jan 01; 24(1):85-96. PubMed ID: 24134879
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  • 11. Glycosyl triazoles as novel insect β-N-acetylhexosaminidase OfHex1 inhibitors: Design, synthesis, molecular docking and MD simulations.
    Dong L, Shen S, Chen W, Lu H, Xu D, Jin S, Yang Q, Zhang J.
    Bioorg Med Chem; 2019 Jun 15; 27(12):2315-2322. PubMed ID: 30528165
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  • 12. Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice.
    Hastings NB, Wang X, Song L, Butts BD, Grotz D, Hargreaves R, Fred Hess J, Hong KK, Huang CR, Hyde L, Laverty M, Lee J, Levitan D, Lu SX, Maguire M, Mahadomrongkul V, McEachern EJ, Ouyang X, Rosahl TW, Selnick H, Stanton M, Terracina G, Vocadlo DJ, Wang G, Duffy JL, Parker EM, Zhang L.
    Mol Neurodegener; 2017 May 18; 12(1):39. PubMed ID: 28521765
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  • 13. Cell-penetrant, nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases.
    Dorfmueller HC, Borodkin VS, Schimpl M, Zheng X, Kime R, Read KD, van Aalten DM.
    Chem Biol; 2010 Nov 24; 17(11):1250-5. PubMed ID: 21095575
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  • 14. O-GlcNAcase: Emerging Mechanism, Substrate Recognition and Small-Molecule Inhibitors.
    Elbatrawy AA, Kim EJ, Nam G.
    ChemMedChem; 2020 Jul 20; 15(14):1244-1257. PubMed ID: 32496638
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  • 15. Tautomeric modification of GlcNAc-thiazoline.
    Knapp S, Abdo M, Ajayi K, Huhn RA, Emge TJ, Kim EJ, Hanover JA.
    Org Lett; 2007 Jun 07; 9(12):2321-4. PubMed ID: 17508759
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  • 16. Inhibition of O-GlcNAcase in perfused rat hearts by NAG-thiazolines at the time of reperfusion is cardioprotective in an O-GlcNAc-dependent manner.
    Laczy B, Marsh SA, Brocks CA, Wittmann I, Chatham JC.
    Am J Physiol Heart Circ Physiol; 2010 Nov 07; 299(5):H1715-27. PubMed ID: 20833964
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  • 17. Isoindoline-based fluorogenic probes bearing a self-immolative linker for the sensitive and selective detection of O-GlcNAcase activity.
    Wu YH, Wang GJ, Guo C, Wang PP, Wang JY, Hu XL, Zang Y, James TD, Li J, He XP.
    Chem Commun (Camb); 2024 Aug 01; 60(63):8240-8243. PubMed ID: 39007923
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  • 18. GlcNAcstatin: a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-glcNAcylation levels.
    Dorfmueller HC, Borodkin VS, Schimpl M, Shepherd SM, Shpiro NA, van Aalten DM.
    J Am Chem Soc; 2006 Dec 27; 128(51):16484-5. PubMed ID: 17177381
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  • 19. Synthesis of NAM-thiazoline derivatives as novel O-GlcNAcase inhibitors.
    Kong H, Chen W, Liu T, Lu H, Yang Q, Dong Y, Liang X, Jin S, Zhang J.
    Carbohydr Res; 2016 Jun 24; 429():54-61. PubMed ID: 27233493
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