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316 related items for PubMed ID: 30430732

  • 1. Phosphomimetic-mediated in vitro rescue of hypertrophic cardiomyopathy linked to R58Q mutation in myosin regulatory light chain.
    Yadav S, Kazmierczak K, Liang J, Sitbon YH, Szczesna-Cordary D.
    FEBS J; 2019 Jan; 286(1):151-168. PubMed ID: 30430732
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  • 2. Functional comparison of phosphomimetic S15D and T160D mutants of myosin regulatory light chain exchanged in cardiac muscle preparations of HCM and WT mice.
    Kazmierczak K, Liang J, Gomez-Guevara M, Szczesna-Cordary D.
    Front Cardiovasc Med; 2022 Jan; 9():988066. PubMed ID: 36204565
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  • 3. In vitro rescue study of a malignant familial hypertrophic cardiomyopathy phenotype by pseudo-phosphorylation of myosin regulatory light chain.
    Muthu P, Liang J, Schmidt W, Moore JR, Szczesna-Cordary D.
    Arch Biochem Biophys; 2014 Jun 15; 552-553():29-39. PubMed ID: 24374283
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  • 4. Phosphorylation Mimetic of Myosin Regulatory Light Chain Mitigates Cardiomyopathy-Induced Myofilament Impairment in Mouse Models of RCM and DCM.
    Kazmierczak K, Liang J, Maura LG, Scott NK, Szczesna-Cordary D.
    Life (Basel); 2023 Jun 28; 13(7):. PubMed ID: 37511838
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  • 5. Constitutive phosphorylation of cardiac myosin regulatory light chain prevents development of hypertrophic cardiomyopathy in mice.
    Yuan CC, Muthu P, Kazmierczak K, Liang J, Huang W, Irving TC, Kanashiro-Takeuchi RM, Hare JM, Szczesna-Cordary D.
    Proc Natl Acad Sci U S A; 2015 Jul 28; 112(30):E4138-46. PubMed ID: 26124132
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  • 6. Mechanistic basis for rescuing hypertrophic cardiomyopathy with myosin regulatory light chain phosphorylation.
    Liang J, Kazmierczak K, Veerasammy M, Yadav S, Takeuchi L, Kanashiro-Takeuchi R, Szczesna-Cordary D.
    Cytoskeleton (Hoboken); 2024 Dec 28; 81(12):806-814. PubMed ID: 38494592
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  • 9. Therapeutic potential of AAV9-S15D-RLC gene delivery in humanized MYL2 mouse model of HCM.
    Yadav S, Yuan CC, Kazmierczak K, Liang J, Huang W, Takeuchi LM, Kanashiro-Takeuchi RM, Szczesna-Cordary D.
    J Mol Med (Berl); 2019 Jul 28; 97(7):1033-1047. PubMed ID: 31101927
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  • 10. Hypertrophic cardiomyopathy mutation R58Q in the myosin regulatory light chain perturbs thick filament-based regulation in cardiac muscle.
    Kampourakis T, Ponnam S, Irving M.
    J Mol Cell Cardiol; 2018 Apr 28; 117():72-81. PubMed ID: 29452157
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  • 11. Diastolic dysfunction in familial hypertrophic cardiomyopathy transgenic model mice.
    Abraham TP, Jones M, Kazmierczak K, Liang HY, Pinheiro AC, Wagg CS, Lopaschuk GD, Szczesna-Cordary D.
    Cardiovasc Res; 2009 Apr 01; 82(1):84-92. PubMed ID: 19150977
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  • 14. Novel familial dilated cardiomyopathy mutation in MYL2 affects the structure and function of myosin regulatory light chain.
    Huang W, Liang J, Yuan CC, Kazmierczak K, Zhou Z, Morales A, McBride KL, Fitzgerald-Butt SM, Hershberger RE, Szczesna-Cordary D.
    FEBS J; 2015 Jun 01; 282(12):2379-93. PubMed ID: 25825243
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  • 19. Mavacamten decreases maximal force and Ca2+ sensitivity in the N47K-myosin regulatory light chain mouse model of hypertrophic cardiomyopathy.
    Awinda PO, Watanabe M, Bishaw Y, Huckabee AM, Agonias KB, Kazmierczak K, Szczesna-Cordary D, Tanner BCW.
    Am J Physiol Heart Circ Physiol; 2021 Feb 01; 320(2):H881-H890. PubMed ID: 33337957
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  • 20. Cross-bridge kinetics in myofibrils containing familial hypertrophic cardiomyopathy R58Q mutation in the regulatory light chain of myosin.
    Mettikolla P, Calander N, Luchowski R, Gryczynski I, Gryczynski Z, Zhao J, Szczesna-Cordary D, Borejdo J.
    J Theor Biol; 2011 Sep 07; 284(1):71-81. PubMed ID: 21723297
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