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566 related items for PubMed ID: 30465514

  • 1. Novel Benzo[B]Furans with Anti-Microtubule Activity Upregulate Expression of Apoptotic Genes and Arrest Leukemia Cells in G2/M Phase.
    Królewska-Golińska K, Cieślak MJ, Sobczak M, Dolot R, Radzikowska-Cieciura E, Napiórkowska M, Wybrańska I, Nawrot B.
    Anticancer Agents Med Chem; 2019; 19(3):375-388. PubMed ID: 30465514
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological evaluation of novel shikonin-benzo[b]furan derivatives as tubulin polymerization inhibitors targeting the colchicine binding site.
    Shao YY, Yin Y, Lian BP, Leng JF, Xia YZ, Kong LY.
    Eur J Med Chem; 2020 Mar 15; 190():112105. PubMed ID: 32035399
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of 1-(benzofuran-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-1,2,3-triazole derivatives as tubulin polymerization inhibitors.
    Qi ZY, Hao SY, Tian HZ, Bian HL, Hui L, Chen SW.
    Bioorg Chem; 2020 Jan 15; 94():103392. PubMed ID: 31669093
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and antitumor molecular mechanism of agents based on amino 2-(3',4',5'-trimethoxybenzoyl)benzo[b]furan: inhibition of tubulin and induction of apoptosis.
    Romagnoli R, Baraldi PG, Lopez-Cara C, Cruz-Lopez O, Carrion MD, Kimatrai Salvador M, Bermejo J, Estévez S, Estévez F, Balzarini J, Brancale A, Ricci A, Chen L, Kim JG, Hamel E.
    ChemMedChem; 2011 Oct 04; 6(10):1841-53. PubMed ID: 21805646
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS, Tabeshpour J, Mirzaei S, Golmakaniyoon S, Tayarani-Najaran Z, Ghasemi A, Ghodsi R.
    Arch Pharm (Weinheim); 2019 Jun 04; 352(6):e1800307. PubMed ID: 31012156
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis, and biological evaluation of a new class of benzo[b]furan derivatives as antiproliferative agents, with in silico predicted antitubulin activity.
    Lauria A, Gentile C, Mingoia F, Palumbo Piccionello A, Bartolotta R, Delisi R, Buscemi S, Martorana A.
    Chem Biol Drug Des; 2018 Jan 04; 91(1):39-49. PubMed ID: 28639390
    [Abstract] [Full Text] [Related]

  • 7. Cytotoxic activity and cytostatic mechanism of novel 2-arylbenzo[b]furans.
    Yang H, Pang JY, Cai YC, Xu ZL, Xian LJ.
    J Pharm Pharmacol; 2006 Sep 04; 58(9):1281-7. PubMed ID: 16945188
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and biological evaluation of benzo[b]furans as inhibitors of tubulin polymerization and inducers of apoptosis.
    Kamal A, Reddy NV, Nayak VL, Reddy VS, Prasad B, Nimbarte VD, Srinivasulu V, Vishnuvardhan MV, Reddy CS.
    ChemMedChem; 2014 Jan 04; 9(1):117-28. PubMed ID: 24203459
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis and structure-activity relationship of 2-(3',4',5'-trimethoxybenzoyl)-benzo[b]furan derivatives as a novel class of inhibitors of tubulin polymerization.
    Romagnoli R, Baraldi PG, Carrion MD, Cara CL, Cruz-Lopez O, Tolomeo M, Grimaudo S, Di Cristina A, Pipitone MR, Balzarini J, Zonta N, Brancale A, Hamel E.
    Bioorg Med Chem; 2009 Oct 01; 17(19):6862-71. PubMed ID: 19736015
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors.
    Oliva P, Romagnoli R, Manfredini S, Brancale A, Ferla S, Hamel E, Ronca R, Maccarinelli F, Giacomini A, Rruga F, Mariotto E, Viola G, Bortolozzi R.
    Eur J Med Chem; 2020 Aug 15; 200():112448. PubMed ID: 32417696
    [Abstract] [Full Text] [Related]

  • 11. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
    Wang YT, Shi TQ, Zhu HL, Liu CH.
    Bioorg Med Chem; 2019 Feb 01; 27(3):502-515. PubMed ID: 30606674
    [Abstract] [Full Text] [Related]

  • 12. Design and synthesis of novel 5-(4-chlorophenyl)furan derivatives with inhibitory activity on tubulin polymerization.
    Moussa SA, A Osman EE, Eid NM, Abou-Seri SM, El Moghazy SM.
    Future Med Chem; 2018 Aug 01; 10(16):1907-1924. PubMed ID: 29966433
    [Abstract] [Full Text] [Related]

  • 13. Synthesis of benzo[d]imidazo[2,1-b]thiazole-chalcone conjugates as microtubule targeting and apoptosis inducing agents.
    Sultana F, Reddy Bonam S, Reddy VG, Nayak VL, Akunuri R, Rani Routhu S, Alarifi A, Halmuthur MSK, Kamal A.
    Bioorg Chem; 2018 Feb 01; 76():1-12. PubMed ID: 29102724
    [Abstract] [Full Text] [Related]

  • 14. New benzimidazole-2-urea derivates as tubulin inhibitors.
    Wang W, Kong D, Cheng H, Tan L, Zhang Z, Zhuang X, Long H, Zhou Y, Xu Y, Yang X, Ding K.
    Bioorg Med Chem Lett; 2014 Sep 01; 24(17):4250-3. PubMed ID: 25091926
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
    Penthala NR, Zong H, Ketkar A, Madadi NR, Janganati V, Eoff RL, Guzman ML, Crooks PA.
    Eur J Med Chem; 2015 Mar 06; 92():212-20. PubMed ID: 25557492
    [Abstract] [Full Text] [Related]

  • 17. (Z)-1-aryl-3-arylamino-2-propen-1-ones, highly active stimulators of tubulin polymerization: synthesis, structure-activity relationship (SAR), tubulin polymerization, and cell growth inhibition studies.
    Reddy MV, Akula B, Cosenza SC, Lee CM, Mallireddigari MR, Pallela VR, Subbaiah DR, Udofa A, Reddy EP.
    J Med Chem; 2012 Jun 14; 55(11):5174-87. PubMed ID: 22587519
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis, biological evaluation, and molecular docking of new benzofuran and indole derivatives as tubulin polymerization inhibitors.
    El-Sayed NF, El-Hussieny M, Ewies EF, El Shehry MF, Awad HM, Fouad MA.
    Drug Dev Res; 2022 Apr 14; 83(2):485-500. PubMed ID: 34523738
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
    Liu R, Zhang S, Huang M, Guo Z, Li L, Li M, Wu L, Guan Q, Zhang W.
    Bioorg Chem; 2021 Oct 14; 115():105220. PubMed ID: 34352709
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and bioevaluation of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazoles as tubulin polymerization inhibitors.
    Liu R, Huang M, Zhang S, Li L, Li M, Sun J, Wu L, Guan Q, Zhang W.
    Eur J Med Chem; 2021 Dec 15; 226():113826. PubMed ID: 34571171
    [Abstract] [Full Text] [Related]

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