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Journal Abstract Search

442 related items for PubMed ID: 30481648

  • 1. 1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inflammatory and analgesic agents with an improved gastric profile: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study.
    Sakr A, Kothayer H, Ibrahim SM, Baraka MM, Rezq S.
    Bioorg Chem; 2019 Mar; 84():76-86. PubMed ID: 30481648
    [Abstract] [Full Text] [Related]

  • 2. Design and synthesis of novel 4-fluorobenzamide-based derivatives as promising anti-inflammatory and analgesic agents with an enhanced gastric tolerability and COX-inhibitory activity.
    Halim PA, Georgey HH, George MY, El Kerdawy AM, Said MF.
    Bioorg Chem; 2021 Oct; 115():105253. PubMed ID: 34390973
    [Abstract] [Full Text] [Related]

  • 3. Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6-diphenyl-1,2,4-triazin-3(2H)-one derivatives bearing 5-substituted 1,3,4-oxadiazole as potential anti-inflammatory and analgesic agents.
    Banerjee AG, Das N, Shengule SA, Srivastava RS, Shrivastava SK.
    Eur J Med Chem; 2015 Aug 28; 101():81-95. PubMed ID: 26117820
    [Abstract] [Full Text] [Related]

  • 4. Discovery of new 2-(3-(naphthalen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazole derivatives with potential analgesic and anti-inflammatory activities: In vitro, in vivo and in silico investigations.
    Mohammed ER, Abd-El-Fatah AH, Mohamed AR, Mahrouse MA, Mohammad MA.
    Bioorg Chem; 2024 Jun 28; 147():107372. PubMed ID: 38653152
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and analgesic/anti-inflammatory evaluation of novel diarylthiazole and diarylimidazole derivatives towards selective COX-1 inhibitors with better gastric profile.
    Abdelazeem AH, El-Saadi MT, Safi El-Din AG, Omar HA, El-Moghazy SM.
    Bioorg Med Chem; 2017 Jan 15; 25(2):665-676. PubMed ID: 27916468
    [Abstract] [Full Text] [Related]

  • 6. New indomethacin analogs as selective COX-2 inhibitors: Synthesis, COX-1/2 inhibitory activity, anti-inflammatory, ulcerogenicity, histopathological, and docking studies.
    Abdellatif KRA, Abdelall EKA, Elshemy HAH, El-Nahass ES, Abdel-Fattah MM, Abdelgawad YYM.
    Arch Pharm (Weinheim); 2021 Apr 15; 354(4):e2000328. PubMed ID: 33314237
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and biological evaluation of new pyrazolone-pyridazine conjugates as anti-inflammatory and analgesic agents.
    Khalil NA, Ahmed EM, Mohamed KO, Nissan YM, Zaitone SA.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2080-9. PubMed ID: 24631365
    [Abstract] [Full Text] [Related]

  • 8. Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study.
    Moussa G, Alaaeddine R, Alaeddine LM, Nassra R, Belal ASF, Ismail A, El-Yazbi AF, Abdel-Ghany YS, Hazzaa A.
    Eur J Med Chem; 2018 Jan 20; 144():635-650. PubMed ID: 29289887
    [Abstract] [Full Text] [Related]

  • 9. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
    Abdelgawad MA, Labib MB, Abdel-Latif M.
    Bioorg Chem; 2017 Oct 20; 74():212-220. PubMed ID: 28865292
    [Abstract] [Full Text] [Related]

  • 10. Molecular docking and synthesis of caffeic acid analogous and its anti-inflammatory, analgesic and ulcerogenic studies.
    Al-Ostoot FH, Zabiulla, Grisha S, Mohammed YHE, Vivek HK, Ara Khanum S.
    Bioorg Med Chem Lett; 2021 Feb 01; 33():127743. PubMed ID: 33316405
    [Abstract] [Full Text] [Related]

  • 11. Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4(3H)-quinazolinones.
    Abdel-Aziz AA, Abou-Zeid LA, ElTahir KEH, Ayyad RR, El-Sayed MA, El-Azab AS.
    Eur J Med Chem; 2016 Oct 04; 121():410-421. PubMed ID: 27318118
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, pharmacological screening and in silico studies of new class of Diclofenac analogues as a promising anti-inflammatory agents.
    Palkar MB, Singhai AS, Ronad PM, Vishwanathswamy AH, Boreddy TS, Veerapur VP, Shaikh MS, Rane RA, Karpoormath R.
    Bioorg Med Chem; 2014 May 15; 22(10):2855-66. PubMed ID: 24751552
    [Abstract] [Full Text] [Related]

  • 13. New benzothiophene derivatives as dual COX-1/2 and 5-LOX inhibitors: synthesis, biological evaluation and docking study.
    El-Miligy MM, Hazzaa AA, El-Messmary H, Nassra RA, El-Hawash SA.
    Future Med Chem; 2017 Apr 15; 9(5):443-468. PubMed ID: 28362117
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, anti-inflammatory, analgesic and COX-1/2 inhibition activities of anilides based on 5,5-diphenylimidazolidine-2,4-dione scaffold: Molecular docking studies.
    Abdel-Aziz AA, El-Azab AS, Abou-Zeid LA, ElTahir KE, Abdel-Aziz NI, Ayyad RR, Al-Obaid AM.
    Eur J Med Chem; 2016 Jun 10; 115():121-31. PubMed ID: 26999325
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and evaluation of some pyrazolo[3,4-d]pyrimidines as anti-inflammatory agents.
    Tageldin GN, Fahmy SM, Ashour HM, Khalil MA, Nassra RA, Labouta IM.
    Bioorg Chem; 2018 Aug 10; 78():358-371. PubMed ID: 29627656
    [Abstract] [Full Text] [Related]

  • 16. Exploring of novel oxazolones and imidazolones as anti-inflammatory and analgesic candidates with cyclooxygenase inhibitory action.
    Rayan SA, George RF, Mohamed NM, Said MF.
    Future Med Chem; 2024 Aug 10; 16(10):963-981. PubMed ID: 38639393
    [Abstract] [Full Text] [Related]

  • 17. Design and synthesis of quinazolinone derivatives as anti-inflammatory agents: pharmacophore modeling and 3D QSAR studies.
    Chaitanya P, Reddy GD, Varun G, Srikanth LM, Prasad VV, Ravindernath A.
    Med Chem; 2014 Aug 10; 10(7):711-23. PubMed ID: 24286396
    [Abstract] [Full Text] [Related]

  • 18. Synthesis, anti-inflammatory screening, molecular docking, and COX-1,2/-5-LOX inhibition profile of some novel quinoline derivatives.
    Chaaban I, Rizk OH, Ibrahim TM, Henen SS, El-Khawass EM, Bayad AE, El-Ashmawy IM, Nematalla HA.
    Bioorg Chem; 2018 Aug 10; 78():220-235. PubMed ID: 29602046
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis of 2,3-disubstitued 4(3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents: COX-1/2 inhibitory activities and molecular docking studies.
    Abdel-Aziz AA, Abou-Zeid LA, ElTahir KE, Mohamed MA, Abu El-Enin MA, El-Azab AS.
    Bioorg Med Chem; 2016 Aug 15; 24(16):3818-28. PubMed ID: 27344214
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, molecular docking and biological evaluation of some newer 2-substituted-4-(benzo[d][1,3]dioxol-5-yl)-6-phenylpyridazin-3(2H)-ones as potential anti-inflammatory and analgesic agents.
    Singh J, Saini V, Kumar A, Bansal R.
    Bioorg Chem; 2017 Apr 15; 71():201-210. PubMed ID: 28236449
    [Abstract] [Full Text] [Related]

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