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Journal Abstract Search

420 related items for PubMed ID: 30482548

  • 1. Design, synthesis and QSAR study of 2'-hydroxy-4'-alkoxy chalcone derivatives that exert cytotoxic activity by the mitochondrial apoptotic pathway.
    Marquina S, Maldonado-Santiago M, Sánchez-Carranza JN, Antúnez-Mojica M, González-Maya L, Razo-Hernández RS, Alvarez L.
    Bioorg Med Chem; 2019 Jan 01; 27(1):43-54. PubMed ID: 30482548
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological evaluation of benzo[d][1,3]dioxol-5-yl chalcones as antiproliferating agents.
    Kamal A, Balakrishna M, Loka Reddy V, Riyaz S, Bagul C, Satyanarayana BM, Venkateswar Rao J.
    Chem Biol Drug Des; 2015 Nov 01; 86(5):1267-84. PubMed ID: 26032623
    [Abstract] [Full Text] [Related]

  • 3. Discovery of thiazole-based-chalcones and 4-hetarylthiazoles as potent anticancer agents: Synthesis, docking study and anticancer activity.
    Farghaly TA, Masaret GS, Muhammad ZA, Harras MF.
    Bioorg Chem; 2020 May 01; 98():103761. PubMed ID: 32200332
    [Abstract] [Full Text] [Related]

  • 4. Novel urea linked ciprofloxacin-chalcone hybrids having antiproliferative topoisomerases I/II inhibitory activities and caspases-mediated apoptosis.
    Mohammed HHH, Abbas SH, Hayallah AM, Abuo-Rahma GEA, Mostafa YA.
    Bioorg Chem; 2021 Jan 01; 106():104422. PubMed ID: 33248713
    [Abstract] [Full Text] [Related]

  • 5. Chalcones with electron-withdrawing and electron-donating substituents: anticancer activity against TRAIL resistant cancer cells, structure-activity relationship analysis and regulation of apoptotic proteins.
    Mai CW, Yaeghoobi M, Abd-Rahman N, Kang YB, Pichika MR.
    Eur J Med Chem; 2014 Apr 22; 77():378-87. PubMed ID: 24675137
    [Abstract] [Full Text] [Related]

  • 6. New chalcone derivative exhibits antiproliferative potential by inducing G2/M cell cycle arrest, mitochondrial-mediated apoptosis and modulation of MAPK signalling pathway.
    Takac P, Kello M, Pilatova MB, Kudlickova Z, Vilkova M, Slepcikova P, Petik P, Mojzis J.
    Chem Biol Interact; 2018 Aug 25; 292():37-49. PubMed ID: 29981726
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis.
    Mohamed TK, Batran RZ, Elseginy SA, Ali MM, Mahmoud AE.
    Bioorg Chem; 2019 Apr 25; 85():253-273. PubMed ID: 30641320
    [Abstract] [Full Text] [Related]

  • 8. Discovery of novel steroidal-chalcone hybrids with potent and selective activity against triple-negative breast cancer.
    Hou Q, Lin X, Lu X, Bai C, Wei H, Luo G, Xiang H.
    Bioorg Med Chem; 2020 Dec 01; 28(23):115763. PubMed ID: 32992255
    [Abstract] [Full Text] [Related]

  • 9. New quinoline/chalcone hybrids as anti-cancer agents: Design, synthesis, and evaluations of cytotoxicity and PI3K inhibitory activity.
    Abbas SH, Abd El-Hafeez AA, Shoman ME, Montano MM, Hassan HA.
    Bioorg Chem; 2019 Feb 01; 82():360-377. PubMed ID: 30428415
    [Abstract] [Full Text] [Related]

  • 10. Hydrogen sulfide releasing enmein-type diterpenoid derivatives as apoptosis inducers through mitochondria-related pathways.
    Xu F, Gao X, Li H, Xu S, Li X, Hu X, Li Z, Xu J, Hua H, Li D.
    Bioorg Chem; 2019 Feb 01; 82():192-203. PubMed ID: 30326401
    [Abstract] [Full Text] [Related]

  • 11. Chalcones incorporated pyrazole ring inhibit proliferation, cell cycle progression, angiogenesis and induce apoptosis of MCF7 cell line.
    Mohamed MF, Mohamed MS, Fathi MM, Shouman SA, Abdelhamid IA.
    Anticancer Agents Med Chem; 2014 Feb 01; 14(9):1282-92. PubMed ID: 25323033
    [Abstract] [Full Text] [Related]

  • 12. Anti-tumour activity of a novel coumarin-chalcone hybrid is mediated through intrinsic apoptotic pathway by inducing PUMA and altering Bax/Bcl-2 ratio.
    Singh N, Sarkar J, Sashidhara KV, Ali S, Sinha S.
    Apoptosis; 2014 Jun 01; 19(6):1017-28. PubMed ID: 24638227
    [Abstract] [Full Text] [Related]

  • 13. Hybrid alpha-bromoacryloylamido chalcones. Design, synthesis and biological evaluation.
    Romagnoli R, Baraldi PG, Carrion MD, Cruz-Lopez O, Cara CL, Balzarini J, Hamel E, Canella A, Fabbri E, Gambari R, Basso G, Viola G.
    Bioorg Med Chem Lett; 2009 Apr 01; 19(7):2022-8. PubMed ID: 19250822
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
    Preti D, Romagnoli R, Rondanin R, Cacciari B, Hamel E, Balzarini J, Liekens S, Schols D, Estévez-Sarmiento F, Quintana J, Estévez F.
    J Enzyme Inhib Med Chem; 2018 Dec 01; 33(1):1225-1238. PubMed ID: 30141353
    [Abstract] [Full Text] [Related]

  • 15. Cytotoxicity, molecular modeling, cell cycle arrest, and apoptotic induction induced by novel tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline chalcones.
    Mohamed MF, Hassaneen HM, Abdelhamid IA.
    Eur J Med Chem; 2018 Jan 01; 143():532-541. PubMed ID: 29207336
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and biological evaluation of novel xanthine derivatives as potential apoptotic antitumor agents.
    Hisham M, Youssif BGM, Osman EEA, Hayallah AM, Abdel-Aziz M.
    Eur J Med Chem; 2019 Aug 15; 176():117-128. PubMed ID: 31108261
    [Abstract] [Full Text] [Related]

  • 17. Molecular Docking Study, Cytotoxicity, Cell Cycle Arrest and Apoptotic Induction of Novel Chalcones Incorporating Thiadiazolyl Isoquinoline in Cervical Cancer.
    Tantawy MA, Sroor FM, Mohamed MF, El-Naggar ME, Saleh FM, Hassaneen HM, Abdelhamid IA.
    Anticancer Agents Med Chem; 2020 Aug 15; 20(1):70-83. PubMed ID: 31696811
    [Abstract] [Full Text] [Related]

  • 18. Discovery of Novel Quinoline-Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity.
    Li W, Xu F, Shuai W, Sun H, Yao H, Ma C, Xu S, Yao H, Zhu Z, Yang DH, Chen ZS, Xu J.
    J Med Chem; 2019 Jan 24; 62(2):993-1013. PubMed ID: 30525584
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and evaluation of chalcone analogues containing a 4-oxoquinazolin-2-yl group as potential anti-tumor agents.
    Han X, Peng B, Xiao BB, Sheng-Li Cao, Yang CR, Wang WZ, Wang FC, Li HY, Yuan XL, Shi R, Liao J, Wang H, Li J, Xu X.
    Eur J Med Chem; 2019 Jan 15; 162():586-601. PubMed ID: 30472605
    [Abstract] [Full Text] [Related]

  • 20. Flavokawain derivative FLS induced G2/M arrest and apoptosis on breast cancer MCF-7 cell line.
    Ali NM, Akhtar MN, Ky H, Lim KL, Abu N, Zareen S, Ho WY, Alan-Ong HK, Tan SW, Alitheen NB, Ismail JB, Yeap SK, Kamarul T.
    Drug Des Devel Ther; 2016 Jan 15; 10():1897-907. PubMed ID: 27358555
    [Abstract] [Full Text] [Related]

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