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231 related items for PubMed ID: 30496567

  • 1. Neuroprotection From Organophosphate-Induced Damage by Novel Phenoxyalkyl Pyridinium Oximes in Rat Brain.
    Pringle RB, Meek EC, Chambers HW, Chambers JE.
    Toxicol Sci; 2018 Dec 01; 166(2):420-427. PubMed ID: 30496567
    [Abstract] [Full Text] [Related]

  • 2. Testing of novel brain-penetrating oxime reactivators of acetylcholinesterase inhibited by nerve agent surrogates.
    Chambers JE, Chambers HW, Meek EC, Pringle RB.
    Chem Biol Interact; 2013 Mar 25; 203(1):135-8. PubMed ID: 23123249
    [Abstract] [Full Text] [Related]

  • 3. Efficacy of novel phenoxyalkyl pyridinium oximes as brain-penetrating reactivators of cholinesterase inhibited by surrogates of sarin and VX.
    Chambers JE, Chambers HW, Funck KE, Meek EC, Pringle RB, Ross MK.
    Chem Biol Interact; 2016 Nov 25; 259(Pt B):154-159. PubMed ID: 27387540
    [Abstract] [Full Text] [Related]

  • 4. Novel centrally active oxime reactivators of acetylcholinesterase inhibited by surrogates of sarin and VX.
    Chambers JE, Meek EC.
    Neurobiol Dis; 2020 Jan 25; 133():104487. PubMed ID: 31158460
    [Abstract] [Full Text] [Related]

  • 5. Novel substituted phenoxyalkyl pyridinium oximes enhance survival and attenuate seizure-like behavior of rats receiving lethal levels of nerve agent surrogates.
    Chambers JE, Meek EC, Bennett JP, Bennett WS, Chambers HW, Leach CA, Pringle RB, Wills RW.
    Toxicology; 2016 Jan 02; 339():51-57. PubMed ID: 26705700
    [Abstract] [Full Text] [Related]

  • 6. Novel Brain-Penetrating Oxime Acetylcholinesterase Reactivators Attenuate Organophosphate-Induced Neuropathology in the Rat Hippocampus.
    Dail MB, Leach CA, Meek EC, Olivier AK, Pringle RB, Green CE, Chambers JE.
    Toxicol Sci; 2019 Jun 01; 169(2):465-474. PubMed ID: 30835286
    [Abstract] [Full Text] [Related]

  • 7. Effects of novel brain-penetrating oxime acetylcholinesterase reactivators on sarin surrogate-induced changes in rat brain gene expression.
    Dail ME, Brino MLM, Chambers JE.
    J Biochem Mol Toxicol; 2021 Jun 01; 35(6):1-10. PubMed ID: 33682265
    [Abstract] [Full Text] [Related]

  • 8. Reactivation by novel pyridinium oximes of rat serum and skeletal muscle acetylcholinesterase inhibited by organophosphates.
    Bennett JP, Meek EC, Chambers JE.
    J Biochem Mol Toxicol; 2024 Jul 01; 38(7):e23750. PubMed ID: 38952032
    [Abstract] [Full Text] [Related]

  • 9. Novel brain-penetrating oximes for reactivation of cholinesterase inhibited by sarin and VX surrogates.
    Chambers JE, Meek EC, Chambers HW.
    Ann N Y Acad Sci; 2016 Jun 01; 1374(1):52-8. PubMed ID: 27153507
    [Abstract] [Full Text] [Related]

  • 10. Novel pyridinium oximes enhance 24-h survivability against a lethal dose of nerve agent surrogate in adult female rats.
    Garcia JM, Meek EC, Chambers JE.
    Toxicology; 2020 Dec 15; 446():152626. PubMed ID: 33159982
    [Abstract] [Full Text] [Related]

  • 11. The effect of PON1 enhancers on reducing acetylcholinesterase inhibition following organophosphate anticholinesterase exposure in rats.
    Meek EC, Chambers HW, Pringle RB, Chambers JE.
    Toxicology; 2015 Oct 02; 336():79-83. PubMed ID: 26275814
    [Abstract] [Full Text] [Related]

  • 12. Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surrogates.
    Chambers JE, Meek EC.
    Ann N Y Acad Sci; 2020 Nov 02; 1479(1):5-12. PubMed ID: 32319115
    [Abstract] [Full Text] [Related]

  • 13. Interactions between xylene-linked carbamoyl bis-pyridinium mono-oximes and organophosphates inhibited-AChE: a kinetic study.
    Sharma R, Gupta B, Acharya J, Kaushik MP, Ghosh KK.
    Toxicology; 2014 Feb 28; 316():1-8. PubMed ID: 24345352
    [Abstract] [Full Text] [Related]

  • 14. Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents.
    Prchalova E, Andrys R, Pejchal J, Kohoutova Z, Knittelova K, Hofmanova T, Skarka A, Dlabkova A, Psotka M, Prchal L, Musilek K, Karasova JZ, Malinak D.
    Arch Toxicol; 2024 Sep 28; 98(9):2937-2952. PubMed ID: 38789714
    [Abstract] [Full Text] [Related]

  • 15. Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro.
    Kuca K, Jun D, Bajgar J.
    Drug Chem Toxicol; 2007 Sep 28; 30(1):31-40. PubMed ID: 17364862
    [Abstract] [Full Text] [Related]

  • 16. Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates.
    Worek F, Reiter G, Eyer P, Szinicz L.
    Arch Toxicol; 2002 Sep 28; 76(9):523-9. PubMed ID: 12242610
    [Abstract] [Full Text] [Related]

  • 17. Pharmacokinetics of three novel pyridinium aldoxime acetylcholinesterase reactivators in female rats.
    Backer BS, Meek EC, Ross MK, Chambers JE.
    Toxicol Appl Pharmacol; 2022 Jul 01; 446():116046. PubMed ID: 35550885
    [Abstract] [Full Text] [Related]

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  • 20. In vitro reactivation of sarin-inhibited human acetylcholinesterase (AChE) by bis-pyridinium oximes connected by xylene linkers.
    Acharya J, Dubey DK, Srivastava AK, Raza SK.
    Toxicol In Vitro; 2011 Feb 01; 25(1):251-6. PubMed ID: 20688148
    [Abstract] [Full Text] [Related]

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