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Journal Abstract Search

283 related items for PubMed ID: 30525584

  • 1. Discovery of Novel Quinoline-Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity.
    Li W, Xu F, Shuai W, Sun H, Yao H, Ma C, Xu S, Yao H, Zhu Z, Yang DH, Chen ZS, Xu J.
    J Med Chem; 2019 Jan 24; 62(2):993-1013. PubMed ID: 30525584
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site.
    Li W, Shuai W, Sun H, Xu F, Bi Y, Xu J, Ma C, Yao H, Zhu Z, Xu S.
    Eur J Med Chem; 2019 Feb 01; 163():428-442. PubMed ID: 30530194
    [Abstract] [Full Text] [Related]

  • 3. Discovery of novel N-benzylbenzamide derivatives as tubulin polymerization inhibitors with potent antitumor activities.
    Zhu H, Li W, Shuai W, Liu Y, Yang L, Tan Y, Zheng T, Yao H, Xu J, Zhu Z, Yang DH, Chen ZS, Xu S.
    Eur J Med Chem; 2021 Apr 15; 216():113316. PubMed ID: 33676300
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  • 5. Synthesis of benzo[d]imidazo[2,1-b]thiazole-chalcone conjugates as microtubule targeting and apoptosis inducing agents.
    Sultana F, Reddy Bonam S, Reddy VG, Nayak VL, Akunuri R, Rani Routhu S, Alarifi A, Halmuthur MSK, Kamal A.
    Bioorg Chem; 2018 Feb 15; 76():1-12. PubMed ID: 29102724
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  • 7. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):640-658. PubMed ID: 33588683
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  • 9. Synthesis, Anticancer Activity and Molecular Modeling Studies of Novel Chalcone Derivatives Containing Indole and Naphthalene Moieties as Tubulin Polymerization Inhibitors.
    Wang G, Peng Z, Li Y.
    Chem Pharm Bull (Tokyo); 2019 Jul 01; 67(7):725-728. PubMed ID: 30982797
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  • 11. New quinoline/chalcone hybrids as anti-cancer agents: Design, synthesis, and evaluations of cytotoxicity and PI3K inhibitory activity.
    Abbas SH, Abd El-Hafeez AA, Shoman ME, Montano MM, Hassan HA.
    Bioorg Chem; 2019 Feb 01; 82():360-377. PubMed ID: 30428415
    [Abstract] [Full Text] [Related]

  • 12. Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
    Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, Neamatallah T, Abdel-Samii ZK, Safo MK, Elshaier YAMM.
    J Enzyme Inhib Med Chem; 2021 Dec 01; 36(1):802-818. PubMed ID: 33730937
    [Abstract] [Full Text] [Related]

  • 13. Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding site.
    Wang G, Liu W, Gong Z, Huang Y, Li Y, Peng Z.
    J Enzyme Inhib Med Chem; 2020 Dec 01; 35(1):139-144. PubMed ID: 31724435
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological evaluation of novel chalcone derivatives as a new class of microtubule destabilizing agents.
    Huang X, Huang R, Li L, Gou S, Wang H.
    Eur J Med Chem; 2017 May 26; 132():11-25. PubMed ID: 28340411
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  • 15. Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site.
    Li W, Sun H, Xu F, Shuai W, Liu J, Xu S, Yao H, Ma C, Zhu Z, Xu J.
    Bioorg Chem; 2019 Apr 26; 85():49-59. PubMed ID: 30599412
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
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  • 18. Discovery of potent cytotoxic ortho-aryl chalcones as new scaffold targeting tubulin and mitosis with affinity-based fluorescence.
    Zhu C, Zuo Y, Wang R, Liang B, Yue X, Wen G, Shang N, Huang L, Chen Y, Du J, Bu X.
    J Med Chem; 2014 Aug 14; 57(15):6364-82. PubMed ID: 25061803
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  • 19. Design, synthesis and biological evaluation of novel acridine and quinoline derivatives as tubulin polymerization inhibitors with anticancer activities.
    Ren Y, Ruan Y, Cheng B, Li L, Liu J, Fang Y, Chen J.
    Bioorg Med Chem; 2021 Sep 15; 46():116376. PubMed ID: 34455231
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  • 20. Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.
    Viola G, Cecconet L, Leszl A, Basso G, Brun P, Salvador A, Dall'Acqua F, Diana P, Barraja P, Cirrincione G.
    Cancer Chemother Pharmacol; 2009 Nov 15; 64(6):1235-51. PubMed ID: 19363609
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