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473 related items for PubMed ID: 30551398

  • 1. Piperlongumine, a piper alkaloid targets Ras/PI3K/Akt/mTOR signaling axis to inhibit tumor cell growth and proliferation in DMH/DSS induced experimental colon cancer.
    Kumar S, Agnihotri N.
    Biomed Pharmacother; 2019 Jan; 109():1462-1477. PubMed ID: 30551398
    [Abstract] [Full Text] [Related]

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  • 3. Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells.
    Shrivastava S, Kulkarni P, Thummuri D, Jeengar MK, Naidu VG, Alvala M, Redddy GB, Ramakrishna S.
    Apoptosis; 2014 Jul; 19(7):1148-64. PubMed ID: 24729100
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  • 5. Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death.
    Makhov P, Golovine K, Teper E, Kutikov A, Mehrazin R, Corcoran A, Tulin A, Uzzo RG, Kolenko VM.
    Br J Cancer; 2014 Feb 18; 110(4):899-907. PubMed ID: 24434432
    [Abstract] [Full Text] [Related]

  • 6. Anticancer activity of safranal against colon carcinoma is due to induction of apoptosis and G2/M cell cycle arrest mediated by suppression of mTOR/PI3K/Akt pathway.
    Zhang Y, Zhao Y, Guo J, Cui H, Liu S.
    J BUON; 2018 Feb 18; 23(3):574-578. PubMed ID: 30003721
    [Abstract] [Full Text] [Related]

  • 7. Deoxyshikonin isolated from Arnebia euchroma inhibits colorectal cancer by down-regulating the PI3K/Akt/mTOR pathway.
    Zhu Y, Zhong Y, Long X, Zhu Z, Zhou Y, Ye H, Zeng X, Zheng X.
    Pharm Biol; 2019 Dec 18; 57(1):412-423. PubMed ID: 31230505
    [Abstract] [Full Text] [Related]

  • 8. Piclamilast mitigates 1,2-dimethylhydrazine induced colon cancer in rats through modulation of Ras/PI3K/Akt/mTOR and NF-κβ signaling.
    Abdel-Wahab BA, Alqhtani H, Walbi IA, Albarqi HA, Aljadaan AM, Khateeb MM, Hassanein EHM.
    Chem Biol Interact; 2021 Dec 01; 350():109686. PubMed ID: 34627785
    [Abstract] [Full Text] [Related]

  • 9. Delicaflavone induces ROS-mediated apoptosis and inhibits PI3K/AKT/mTOR and Ras/MEK/Erk signaling pathways in colorectal cancer cells.
    Yao W, Lin Z, Shi P, Chen B, Wang G, Huang J, Sui Y, Liu Q, Li S, Lin X, Liu Q, Yao H.
    Biochem Pharmacol; 2020 Jan 01; 171():113680. PubMed ID: 31669234
    [Abstract] [Full Text] [Related]

  • 10. Oxymatrine synergistically enhances antitumor activity of oxaliplatin in colon carcinoma through PI3K/AKT/mTOR pathway.
    Liu Y, Bi T, Wang Z, Wu G, Qian L, Gao Q, Shen G.
    Apoptosis; 2016 Dec 01; 21(12):1398-1407. PubMed ID: 27671687
    [Abstract] [Full Text] [Related]

  • 11. Piperlongumine induces G2/M phase arrest and apoptosis in cholangiocarcinoma cells through the ROS-JNK-ERK signaling pathway.
    Thongsom S, Suginta W, Lee KJ, Choe H, Talabnin C.
    Apoptosis; 2017 Nov 01; 22(11):1473-1484. PubMed ID: 28913568
    [Abstract] [Full Text] [Related]

  • 12. Piperine induces autophagy of colon cancer cells: Dual modulation of AKT/mTOR signaling pathway and ROS production.
    Xia J, Guo P, Yang J, Zhang T, Pan K, Wei H.
    Biochem Biophys Res Commun; 2024 Oct 08; 728():150340. PubMed ID: 38968770
    [Abstract] [Full Text] [Related]

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  • 14. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST, Qin Y, Zhou ZW, He ZX, Zhang X, Yang T, Yang YX, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Oct 08; 9():1601-26. PubMed ID: 25834400
    [Abstract] [Full Text] [Related]

  • 15. Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways.
    Leu WJ, Swain ShP, Chan SH, Hsu JL, Liu SP, Chan ML, Yu CC, Hsu LC, Chou YL, Chang WL, Hou DR, Guh JH.
    Oncotarget; 2016 Nov 22; 7(47):76995-77009. PubMed ID: 27769069
    [Abstract] [Full Text] [Related]

  • 16. Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer.
    Moench R, Grimmig T, Kannen V, Tripathi S, Faber M, Moll EM, Chandraker A, Lissner R, Germer CT, Waaga-Gasser AM, Gasser M.
    Oncotarget; 2016 Oct 18; 7(42):68749-68767. PubMed ID: 27626684
    [Abstract] [Full Text] [Related]

  • 17. Chloroform extract from Sophora Tonkinensis Gagnep. inhibit proliferation, migration, invasion and promote apoptosis of nasopharyngeal carcinoma cells by silencing the PI3K/AKT/mTOR signaling pathway.
    ShuoWang, Song Z, Gong X, Ou C, Zhang W, Wang J, Yao C, Qin S, Yan B, Li Q, Wei K, Hou X, Zhou X, Miao J.
    J Ethnopharmacol; 2021 May 10; 271():113879. PubMed ID: 33524509
    [Abstract] [Full Text] [Related]

  • 18. Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway.
    Han B, Jiang P, Li Z, Yu Y, Huang T, Ye X, Li X.
    Phytomedicine; 2018 Sep 15; 48():152-160. PubMed ID: 30195873
    [Abstract] [Full Text] [Related]

  • 19. Brevilin A induces apoptosis and autophagy of colon adenocarcinoma cell CT26 via mitochondrial pathway and PI3K/AKT/mTOR inactivation.
    You P, Wu H, Deng M, Peng J, Li F, Yang Y.
    Biomed Pharmacother; 2018 Feb 15; 98():619-625. PubMed ID: 29289836
    [Abstract] [Full Text] [Related]

  • 20. A marine sponge alkaloid derivative 4-chloro fascaplysin inhibits tumor growth and VEGF mediated angiogenesis by disrupting PI3K/Akt/mTOR signaling cascade.
    Sharma S, Guru SK, Manda S, Kumar A, Mintoo MJ, Prasad VD, Sharma PR, Mondhe DM, Bharate SB, Bhushan S.
    Chem Biol Interact; 2017 Sep 25; 275():47-60. PubMed ID: 28756150
    [Abstract] [Full Text] [Related]

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