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567 related items for PubMed ID: 30569594

  • 1. Critical role of C5a in sickle cell disease.
    Vercellotti GM, Dalmasso AP, Schaid TR, Nguyen J, Chen C, Ericson ME, Abdulla F, Killeen T, Lindorfer MA, Taylor RP, Belcher JD.
    Am J Hematol; 2019 Mar; 94(3):327-337. PubMed ID: 30569594
    [Abstract] [Full Text] [Related]

  • 2. MASP-2 and MASP-3 inhibitors block complement activation, inflammation, and microvascular stasis in a murine model of vaso-occlusion in sickle cell disease.
    Belcher JD, Nguyen J, Chen C, Abdulla F, Conglin R, Ivy ZK, Cummings J, Dudler T, Vercellotti GM.
    Transl Res; 2022 Nov; 249():1-12. PubMed ID: 35878790
    [Abstract] [Full Text] [Related]

  • 3. Endothelial TLR4 Expression Mediates Vaso-Occlusive Crisis in Sickle Cell Disease.
    Beckman JD, Abdullah F, Chen C, Kirchner R, Rivera-Rodriguez D, Kiser ZM, Nguyen A, Zhang P, Nguyen J, Hebbel RP, Belcher JD, Vercellotti GM.
    Front Immunol; 2020 Nov; 11():613278. PubMed ID: 33542720
    [Abstract] [Full Text] [Related]

  • 4. Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease.
    Belcher JD, Chen C, Nguyen J, Milbauer L, Abdulla F, Alayash AI, Smith A, Nath KA, Hebbel RP, Vercellotti GM.
    Blood; 2014 Jan 16; 123(3):377-90. PubMed ID: 24277079
    [Abstract] [Full Text] [Related]

  • 5. The fucosylation inhibitor, 2-fluorofucose, inhibits vaso-occlusion, leukocyte-endothelium interactions and NF-ĸB activation in transgenic sickle mice.
    Belcher JD, Chen C, Nguyen J, Abdulla F, Nguyen P, Nguyen M, Okeley NM, Benjamin DR, Senter PD, Vercellotti GM.
    PLoS One; 2015 Jan 16; 10(2):e0117772. PubMed ID: 25706118
    [Abstract] [Full Text] [Related]

  • 6. Cold exposure induces vaso-occlusion and pain in sickle mice that depend on complement activation.
    Ivy ZK, Belcher JD, Khasabova IA, Chen C, Juliette JP, Abdulla F, Ruan C, Allen K, Nguyen J, Rogness VM, Beckman JD, Khasabov SG, Gupta K, Taylor RP, Simone DA, Vercellotti GM.
    Blood; 2023 Nov 30; 142(22):1918-1927. PubMed ID: 37774369
    [Abstract] [Full Text] [Related]

  • 7. Inter-α-inhibitor Ameliorates Endothelial Inflammation in Sepsis.
    Stober VP, Lim YP, Opal S, Zhuo L, Kimata K, Garantziotis S.
    Lung; 2019 Jun 30; 197(3):361-369. PubMed ID: 31028466
    [Abstract] [Full Text] [Related]

  • 8. Differential contribution of C5aR and C5b-9 pathways to renal thrombic microangiopathy and macrovascular thrombosis in mice carrying an atypical hemolytic syndrome-related factor H mutation.
    Ueda Y, Miwa T, Ito D, Kim H, Sato S, Gullipalli D, Zhou L, Golla M, Song D, Dunaief JL, Palmer MB, Song WC.
    Kidney Int; 2019 Jul 30; 96(1):67-79. PubMed ID: 30910380
    [Abstract] [Full Text] [Related]

  • 9. Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia.
    Belcher JD, Gomperts E, Nguyen J, Chen C, Abdulla F, Kiser ZM, Gallo D, Levy H, Otterbein LE, Vercellotti GM.
    PLoS One; 2018 Jul 30; 13(10):e0205194. PubMed ID: 30308028
    [Abstract] [Full Text] [Related]

  • 10. Endothelial activation by platelets from sickle cell anemia patients.
    Proença-Ferreira R, Brugnerotto AF, Garrido VT, Dominical VM, Vital DM, Ribeiro Mde F, dos Santos ME, Traina F, Olalla-Saad ST, Costa FF, Conran N.
    PLoS One; 2014 Jul 30; 9(2):e89012. PubMed ID: 24551209
    [Abstract] [Full Text] [Related]

  • 11. Inhibiting the C5-C5a receptor axis.
    Woodruff TM, Nandakumar KS, Tedesco F.
    Mol Immunol; 2011 Aug 30; 48(14):1631-42. PubMed ID: 21549429
    [Abstract] [Full Text] [Related]

  • 12. Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model.
    Atkinson SM, Nansen A, Usher PA, Sondergaard BC, Mackay CR, Friedrichsen B, Chang CC, Tang R, Skov S, Haase C, Hornum L.
    Autoimmunity; 2015 Aug 30; 48(7):460-70. PubMed ID: 25915570
    [Abstract] [Full Text] [Related]

  • 13. Activated monocytes in sickle cell disease: potential role in the activation of vascular endothelium and vaso-occlusion.
    Belcher JD, Marker PH, Weber JP, Hebbel RP, Vercellotti GM.
    Blood; 2000 Oct 01; 96(7):2451-9. PubMed ID: 11001897
    [Abstract] [Full Text] [Related]

  • 14. Real-Time Imaging of Interactions of Neutrophils with Cryptococcus neoformans Demonstrates a Crucial Role of Complement C5a-C5aR Signaling.
    Sun D, Zhang M, Liu G, Wu H, Zhu X, Zhou H, Shi M.
    Infect Immun; 2016 Jan 01; 84(1):216-29. PubMed ID: 26502909
    [Abstract] [Full Text] [Related]

  • 15. Complement component c5a is integral to the febrile response of mice to lipopolysaccharide.
    Li S, Boackle SA, Holers VM, Lambris JD, Blatteis CM.
    Neuroimmunomodulation; 2005 Jan 01; 12(2):67-80. PubMed ID: 15785108
    [Abstract] [Full Text] [Related]

  • 16. Mesenchymal stem cells alleviate acute kidney injury by down-regulating C5a/C5aR pathway activation.
    Tang M, Zhang K, Li Y, He QH, Li GQ, Zheng QY, Zhang KQ.
    Int Urol Nephrol; 2018 Aug 01; 50(8):1545-1553. PubMed ID: 29594894
    [Abstract] [Full Text] [Related]

  • 17. Critical role of endothelial cell activation in hypoxia-induced vasoocclusion in transgenic sickle mice.
    Belcher JD, Mahaseth H, Welch TE, Vilback AE, Sonbol KM, Kalambur VS, Bowlin PR, Bischof JC, Hebbel RP, Vercellotti GM.
    Am J Physiol Heart Circ Physiol; 2005 Jun 01; 288(6):H2715-25. PubMed ID: 15665055
    [Abstract] [Full Text] [Related]

  • 18. Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation.
    Skjeflo EW, Christiansen D, Fure H, Ludviksen JK, Woodruff TM, Espevik T, Nielsen EW, Brekke OL, Mollnes TE.
    J Thromb Haemost; 2018 May 01; 16(5):905-918. PubMed ID: 29437288
    [Abstract] [Full Text] [Related]

  • 19. Cobalt chloride-induced signaling in endothelium leading to the augmented adherence of sickle red blood cells and transendothelial migration of monocyte-like HL-60 cells is blocked by PAF-receptor antagonist.
    Sultana C, Shen Y, Johnson C, Kalra VK.
    J Cell Physiol; 1999 Apr 01; 179(1):67-78. PubMed ID: 10082134
    [Abstract] [Full Text] [Related]

  • 20. Blockade of the C5a-C5aR axis alleviates lung damage in hDPP4-transgenic mice infected with MERS-CoV.
    Jiang Y, Zhao G, Song N, Li P, Chen Y, Guo Y, Li J, Du L, Jiang S, Guo R, Sun S, Zhou Y.
    Emerg Microbes Infect; 2018 Apr 24; 7(1):77. PubMed ID: 29691378
    [Abstract] [Full Text] [Related]

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