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Journal Abstract Search

207 related items for PubMed ID: 30580917

  • 1. Design, synthesis and biological evaluation of novel HIV-1 protease inhibitors with pentacyclic triterpenoids as P2-ligands.
    Zhu M, Du XN, Li YG, Zhang GN, Wang JX, Wang YC.
    Bioorg Med Chem Lett; 2019 Feb 01; 29(3):357-361. PubMed ID: 30580917
    [Abstract] [Full Text] [Related]

  • 2. HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
    Rusere LN, Lockbaum GJ, Lee SK, Henes M, Kosovrasti K, Spielvogel E, Nalivaika EA, Swanstrom R, Yilmaz NK, Schiffer CA, Ali A.
    J Med Chem; 2019 Sep 12; 62(17):8062-8079. PubMed ID: 31386368
    [Abstract] [Full Text] [Related]

  • 3. Design and evaluation of novel piperidine HIV-1 protease inhibitors with potency against DRV-resistant variants.
    Zhu M, Zhou H, Ma L, Dong B, Zhou J, Zhang G, Wang M, Wang J, Cen S, Wang Y.
    Eur J Med Chem; 2021 Aug 05; 220():113450. PubMed ID: 33906049
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  • 4. Structure-based design, synthesis, X-ray studies, and biological evaluation of novel HIV-1 protease inhibitors containing isophthalamide-derived P2-ligands.
    Ghosh AK, Takayama J, Kassekert LA, Ella-Menye JR, Yashchuk S, Agniswamy J, Wang YF, Aoki M, Amano M, Weber IT, Mitsuya H.
    Bioorg Med Chem Lett; 2015 Nov 01; 25(21):4903-4909. PubMed ID: 26096678
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  • 5. Synthesis and biological evaluation of novel HIV-1 protease inhibitors using tertiary amine as P2-ligands.
    Yang ZH, Bai XG, Zhou L, Wang JX, Liu HT, Wang YC.
    Bioorg Med Chem Lett; 2015 May 01; 25(9):1880-3. PubMed ID: 25838144
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  • 7. Piperidine scaffold as the novel P2-ligands in cyclopropyl-containing HIV-1 protease inhibitors: Structure-based design, synthesis, biological evaluation and docking study.
    Zhou H, Zhu M, Ma L, Zhou J, Dong B, Zhang G, Cen S, Wang Y, Wang J.
    PLoS One; 2020 May 01; 15(7):e0235483. PubMed ID: 32697773
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  • 9. Lysine sulfonamides as novel HIV-protease inhibitors: Nepsilon-acyl aromatic alpha-amino acids.
    Stranix BR, Lavallée JF, Sévigny G, Yelle J, Perron V, LeBerre N, Herbart D, Wu JJ.
    Bioorg Med Chem Lett; 2006 Jul 01; 16(13):3459-62. PubMed ID: 16644213
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  • 10. Potent HIV-1 Protease Inhibitors Containing Carboxylic and Boronic Acids: Effect on Enzyme Inhibition and Antiviral Activity and Protein-Ligand X-ray Structural Studies.
    Ghosh AK, Xia Z, Kovela S, Robinson WL, Johnson ME, Kneller DW, Wang YF, Aoki M, Takamatsu Y, Weber IT, Mitsuya H.
    ChemMedChem; 2019 Nov 06; 14(21):1863-1872. PubMed ID: 31549492
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  • 11. Preliminary SAR and biological evaluation of potent HIV-1 protease inhibitors with pyrimidine bases as novel P2 ligands to enhance activity against DRV-resistant HIV-1 variants.
    Zhu M, Ma L, Zhou H, Dong B, Wang Y, Wang Z, Zhou J, Zhang G, Wang J, Liang C, Cen S, Wang Y.
    Eur J Med Chem; 2020 Jan 01; 185():111866. PubMed ID: 31734023
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  • 13. Design and synthesis of potent HIV-1 protease inhibitors incorporating hydroxyprolinamides as novel P2 ligands.
    Gao BL, Zhang CM, Yin YZ, Tang LQ, Liu ZP.
    Bioorg Med Chem Lett; 2011 Jun 15; 21(12):3730-3. PubMed ID: 21555220
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  • 14. Synthesis and antiviral activity of new anti-HIV amprenavir bioisosteres.
    Rocheblave L, Bihel F, De Michelis C, Priem G, Courcambeck J, Bonnet B, Chermann JC, Kraus JL.
    J Med Chem; 2002 Jul 18; 45(15):3321-4. PubMed ID: 12109915
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  • 16. Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P(2) ligands: structure-activity studies and biological evaluation.
    Ghosh AK, Chapsal BD, Baldridge A, Steffey MP, Walters DE, Koh Y, Amano M, Mitsuya H.
    J Med Chem; 2011 Jan 27; 54(2):622-34. PubMed ID: 21194227
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  • 17. Discovery of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryl-oxazolidinone-5-carboxamides as novel P2 ligands.
    Ali A, Reddy GS, Cao H, Anjum SG, Nalam MN, Schiffer CA, Rana TM.
    J Med Chem; 2006 Dec 14; 49(25):7342-56. PubMed ID: 17149864
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  • 18. Structure-based design of potent HIV-1 protease inhibitors with modified P1-biphenyl ligands: synthesis, biological evaluation, and enzyme-inhibitor X-ray structural studies.
    Ghosh AK, Yu X, Osswald HL, Agniswamy J, Wang YF, Amano M, Weber IT, Mitsuya H.
    J Med Chem; 2015 Jul 09; 58(13):5334-43. PubMed ID: 26107245
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  • 19. Synthesis and evaluation of A-seco type triterpenoids for anti-HIV-1protease activity.
    Wei Y, Ma CM, Hattori M.
    Eur J Med Chem; 2009 Oct 09; 44(10):4112-20. PubMed ID: 19493591
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  • 20. Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure-Activity Studies, Biological and X-ray Structural Analysis.
    Ghosh AK, R Nyalapatla P, Kovela S, Rao KV, Brindisi M, Osswald HL, Amano M, Aoki M, Agniswamy J, Wang YF, Weber IT, Mitsuya H.
    J Med Chem; 2018 May 24; 61(10):4561-4577. PubMed ID: 29763303
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