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Journal Abstract Search

635 related items for PubMed ID: 30606674

  • 21. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.
    Yang F, He CP, Diao PC, Hong KH, Rao JJ, Zhao PL.
    Bioorg Med Chem Lett; 2019 Jan 01; 29(1):22-27. PubMed ID: 30448234
    [Abstract] [Full Text] [Related]

  • 22. Synthesis and biological evaluation of Schizandrin derivatives as tubulin polymerization inhibitors.
    Dileep Kumar G, Siva B, Bharathi K, Devi A, Pavan Kumar P, Anusha K, Lambhate S, Karunakar T, Kumar Tiwari A, Suresh Babu K.
    Bioorg Med Chem Lett; 2020 Aug 15; 30(16):127354. PubMed ID: 32631552
    [Abstract] [Full Text] [Related]

  • 23. Synthesis and biological evaluation of (1-aryl-1H-pyrazol-4-yl) (3,4,5-trimethoxyphenyl)methanone derivatives as tubulin inhibitors.
    Zhai M, Wang L, Liu S, Wang L, Yan P, Wang J, Zhang J, Guo H, Guan Q, Bao K, Wu Y, Zhang W.
    Eur J Med Chem; 2018 Aug 05; 156():137-147. PubMed ID: 30006160
    [Abstract] [Full Text] [Related]

  • 24. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 25. Synthesis and biological evaluation of imidazo[1,5-a]pyridine-benzimidazole hybrids as inhibitors of both tubulin polymerization and PI3K/Akt pathway.
    Kamal A, Rao AV, Nayak VL, Reddy NV, Swapna K, Ramakrishna G, Alvala M.
    Org Biomol Chem; 2014 Dec 28; 12(48):9864-80. PubMed ID: 25354805
    [Abstract] [Full Text] [Related]

  • 26. Development of Benzimidazole-Substituted Spirocyclopropyl Oxindole Derivatives as Cytotoxic Agents: Tubulin Polymerization Inhibition and Apoptosis Inducing Studies.
    Sakla AP, Bazaz MR, Mahale A, Sharma P, Valapil DG, Kulkarni OP, Dandekar MP, Shankaraiah N.
    ChemMedChem; 2024 Jun 17; 19(12):e202400052. PubMed ID: 38517377
    [Abstract] [Full Text] [Related]

  • 27. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S.
    Anticancer Agents Med Chem; 2021 Jun 17; 21(8):1047-1055. PubMed ID: 32981511
    [Abstract] [Full Text] [Related]

  • 28. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S.
    Eur J Med Chem; 2018 Jan 20; 144():797-816. PubMed ID: 29291446
    [Abstract] [Full Text] [Related]

  • 29. Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization.
    Jadala C, Sathish M, Anchi P, Tokala R, Lakshmi UJ, Reddy VG, Shankaraiah N, Godugu C, Kamal A.
    ChemMedChem; 2019 Dec 17; 14(24):2052-2060. PubMed ID: 31674147
    [Abstract] [Full Text] [Related]

  • 30. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
    Liu R, Zhang S, Huang M, Guo Z, Li L, Li M, Wu L, Guan Q, Zhang W.
    Bioorg Chem; 2021 Oct 17; 115():105220. PubMed ID: 34352709
    [Abstract] [Full Text] [Related]

  • 31. Design, synthesis, molecular modeling, and biological evaluation of pyrazole-naphthalene derivatives as potential anticancer agents on MCF-7 breast cancer cells by inhibiting tubulin polymerization.
    Wang G, Liu W, Peng Z, Huang Y, Gong Z, Li Y.
    Bioorg Chem; 2020 Oct 17; 103():104141. PubMed ID: 32750611
    [Abstract] [Full Text] [Related]

  • 32. Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor.
    Ameri A, Khodarahmi G, Forootanfar H, Hassanzadeh F, Hakimelahi GH.
    Chem Biodivers; 2018 Mar 17; 15(3):e1700518. PubMed ID: 29292595
    [Abstract] [Full Text] [Related]

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  • 34. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 35. Discovery of novel 2-substituted 2, 3-dihydroquinazolin-4(1H)-one derivatives as tubulin polymerization inhibitors for anticancer therapy: The in vitro and in vivo biological evaluation.
    Shi C, Yang B, He Z, Yang J, Li L, Song J, Xu S, Song W, Yang J.
    Eur J Med Chem; 2024 Nov 05; 277():116766. PubMed ID: 39163776
    [Abstract] [Full Text] [Related]

  • 36. 1,3,4-oxadiazole-2-thione Derivatives; Novel Approach for Anticancer and Tubulin Polymerization Inhibitory Activities.
    Abdel-Aziz M, Metwally KA, Gamal-Eldeen AM, Aly OM.
    Anticancer Agents Med Chem; 2015 Nov 05; 16(2):269-77. PubMed ID: 26343141
    [Abstract] [Full Text] [Related]

  • 37. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
    Kamal A, Srinivasa Reddy T, Polepalli S, Shalini N, Reddy VG, Subba Rao AV, Jain N, Shankaraiah N.
    Bioorg Med Chem; 2014 Oct 01; 22(19):5466-75. PubMed ID: 25131956
    [Abstract] [Full Text] [Related]

  • 38. Synthesis and bioevaluation of N-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-amines as tubulin polymerization inhibitors with anti-angiogenic effects.
    Hao SY, Qi ZY, Wang S, Wang XR, Chen SW.
    Bioorg Med Chem; 2021 Feb 01; 31():115985. PubMed ID: 33421913
    [Abstract] [Full Text] [Related]

  • 39. Novel Benzo[B]Furans with Anti-Microtubule Activity Upregulate Expression of Apoptotic Genes and Arrest Leukemia Cells in G2/M Phase.
    Królewska-Golińska K, Cieślak MJ, Sobczak M, Dolot R, Radzikowska-Cieciura E, Napiórkowska M, Wybrańska I, Nawrot B.
    Anticancer Agents Med Chem; 2019 Feb 01; 19(3):375-388. PubMed ID: 30465514
    [Abstract] [Full Text] [Related]

  • 40. Discovery, biological evaluation, structure-activity relationships and mechanism of action of pyrazolo[3,4-b]pyridin-6-one derivatives as a new class of anticancer agents.
    Guo Q, Luo Y, Zhai S, Jiang Z, Zhao C, Xu J, Wang L.
    Org Biomol Chem; 2019 Jun 26; 17(25):6201-6214. PubMed ID: 31179474
    [Abstract] [Full Text] [Related]

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