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Journal Abstract Search

250 related items for PubMed ID: 30608603

  • 1. It takes a team: a gain-of-function story of p53-R249S.
    Wang H, Liao P, Zeng SX, Lu H.
    J Mol Cell Biol; 2019 Apr 01; 11(4):277-283. PubMed ID: 30608603
    [Abstract] [Full Text] [Related]

  • 2. Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding.
    Liao P, Zeng SX, Zhou X, Chen T, Zhou F, Cao B, Jung JH, Del Sal G, Luo S, Lu H.
    Mol Cell; 2017 Dec 21; 68(6):1134-1146.e6. PubMed ID: 29225033
    [Abstract] [Full Text] [Related]

  • 3. Prevalence of aflatoxin induced p53 mutation at codon 249 (R249s) in hepatocellular carcinoma patients with and without hepatitis B surface antigen (HBsAg).
    Chittmittrapap S, Chieochansin T, Chaiteerakij R, Treeprasertsuk S, Klaikaew N, Tangkijvanich P, Komolmit P, Poovorawan Y.
    Asian Pac J Cancer Prev; 2013 Dec 21; 14(12):7675-9. PubMed ID: 24460352
    [Abstract] [Full Text] [Related]

  • 4. Co-targeting p53-R249S and CDK4 synergistically suppresses survival of hepatocellular carcinoma cells.
    Wang H, Liao P, Zeng SX, Lu H.
    Cancer Biol Ther; 2020 Dec 21; 21(3):269-277. PubMed ID: 31747859
    [Abstract] [Full Text] [Related]

  • 5. The p53 mutation spectrum in hepatocellular carcinoma from Guangxi, China : role of chronic hepatitis B virus infection and aflatoxin B1 exposure.
    Qi LN, Bai T, Chen ZS, Wu FX, Chen YY, De Xiang B, Peng T, Han ZG, Li LQ.
    Liver Int; 2015 Mar 21; 35(3):999-1009. PubMed ID: 24461059
    [Abstract] [Full Text] [Related]

  • 6. Effects of the TP53 p.R249S mutant on proliferation and clonogenic properties in human hepatocellular carcinoma cell lines: interaction with hepatitis B virus X protein.
    Gouas DA, Shi H, Hautefeuille AH, Ortiz-Cuaran SL, Legros PC, Szymanska KJ, Galy O, Egevad LA, Abedi-Ardekani B, Wiman KG, Hantz O, Caron de Fromentel C, Chemin IA, Hainaut PL.
    Carcinogenesis; 2010 Aug 21; 31(8):1475-82. PubMed ID: 20538734
    [Abstract] [Full Text] [Related]

  • 7. TP53 R249S mutation, genetic variations in HBX and risk of hepatocellular carcinoma in The Gambia.
    Gouas DA, Villar S, Ortiz-Cuaran S, Legros P, Ferro G, Kirk GD, Lesi OA, Mendy M, Bah E, Friesen MD, Groopman J, Chemin I, Hainaut P.
    Carcinogenesis; 2012 Jun 21; 33(6):1219-24. PubMed ID: 22759751
    [Abstract] [Full Text] [Related]

  • 8. Hepatitis B virus genetic variation and TP53 R249S mutation in patients with hepatocellular carcinoma in Thailand.
    Thongbai C, Sa-nguanmoo P, Kranokpiruk P, Poovorawan K, Poovorawan Y, Tangkijvanich P.
    Asian Pac J Cancer Prev; 2013 Jun 21; 14(6):3555-9. PubMed ID: 23886144
    [Abstract] [Full Text] [Related]

  • 9. The Effect of p53-R249S on the Suppression of Hepatocellular Carcinoma Cells Survival Induced by Podophyllum Derivatives.
    Chen H, Zhang M, Wang Z, Li L, Li Q, Wang H.
    Anticancer Agents Med Chem; 2020 Jun 21; 20(7):865-874. PubMed ID: 32067620
    [Abstract] [Full Text] [Related]

  • 10. Seasonal variation in TP53 R249S-mutated serum DNA with aflatoxin exposure and hepatitis B virus infection.
    Villar S, Le Roux-Goglin E, Gouas DA, Plymoth A, Ferro G, Boniol M, Lereau M, Bah E, Hall AJ, Wild CP, Mendy M, Norder H, van der Sande M, Whittle H, Friesen MD, Groopman JD, Hainaut P.
    Environ Health Perspect; 2011 Nov 21; 119(11):1635-40. PubMed ID: 21768053
    [Abstract] [Full Text] [Related]

  • 11. TP53 R249S mutations, exposure to aflatoxin, and occurrence of hepatocellular carcinoma in a cohort of chronic hepatitis B virus carriers from Qidong, China.
    Szymañska K, Chen JG, Cui Y, Gong YY, Turner PC, Villar S, Wild CP, Parkin DM, Hainaut P.
    Cancer Epidemiol Biomarkers Prev; 2009 May 21; 18(5):1638-43. PubMed ID: 19366907
    [Abstract] [Full Text] [Related]

  • 12. Genome-wide association study of the TP53 R249S mutation in hepatocellular carcinoma with aflatoxin B1 exposure and infection with hepatitis B virus.
    Han C, Yu T, Qin W, Liao X, Huang J, Liu Z, Yu L, Liu X, Chen Z, Yang C, Wang X, Mo S, Zhu G, Su H, Li J, Qin X, Gui Y, Mo Z, Li L, Peng T.
    J Gastrointest Oncol; 2020 Dec 21; 11(6):1333-1349. PubMed ID: 33457005
    [Abstract] [Full Text] [Related]

  • 13. Nicotine Promotes WRL68 Cells Proliferation Due to the Mutant p53 Gain-of-Function by Activating CDK6-p53-RS-PIN1-STAT1 Signaling Pathway.
    Wang H, Chen L, Zhou T, Zhang Z, Zeng C.
    Chem Res Toxicol; 2020 Sep 21; 33(9):2361-2373. PubMed ID: 32820905
    [Abstract] [Full Text] [Related]

  • 14. Aflatoxin-induced TP53 R249S mutation in hepatocellular carcinoma in Thailand: association with tumors developing in the absence of liver cirrhosis.
    Villar S, Ortiz-Cuaran S, Abedi-Ardekani B, Gouas D, Nogueira da Costa A, Plymoth A, Khuhaprema T, Kalalak A, Sangrajrang S, Friesen MD, Groopman JD, Hainaut P.
    PLoS One; 2012 Sep 21; 7(6):e37707. PubMed ID: 22675488
    [Abstract] [Full Text] [Related]

  • 15. TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk.
    Lam YK, Yu J, Huang H, Ding X, Wong AM, Leung HH, Chan AW, Ng KK, Xu M, Wang X, Wong N.
    Hepatology; 2023 Sep 01; 78(3):727-740. PubMed ID: 36221953
    [Abstract] [Full Text] [Related]

  • 16. Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53.
    Fei Q, Shang K, Zhang J, Chuai S, Kong D, Zhou T, Fu S, Liang Y, Li C, Chen Z, Zhao Y, Yu Z, Huang Z, Hu M, Ying H, Chen Z, Zhang Y, Xing F, Zhu J, Xu H, Zhao K, Lu C, Atadja P, Xiao ZX, Li E, Shou J.
    Nat Commun; 2015 Oct 16; 6():8651. PubMed ID: 26471002
    [Abstract] [Full Text] [Related]

  • 17. Expression and significance of Pin1, β-catenin and cyclin D1 in hepatocellular carcinoma.
    Ao R, Zhang DR, Du YQ, Wang Y.
    Mol Med Rep; 2014 Oct 16; 10(4):1893-8. PubMed ID: 25109821
    [Abstract] [Full Text] [Related]

  • 18. Recombinant human adenovirus-p53 injection induced apoptosis in hepatocellular carcinoma cell lines mediated by p53-Fbxw7 pathway, which controls c-Myc and cyclin E.
    Tu K, Zheng X, Zhou Z, Li C, Zhang J, Gao J, Yao Y, Liu Q.
    PLoS One; 2013 Oct 16; 8(7):e68574. PubMed ID: 23840897
    [Abstract] [Full Text] [Related]

  • 19. Mutations in the p53 tumor suppressor gene in tree shrew hepatocellular carcinoma associated with hepatitis B virus infection and intake of aflatoxin B1.
    Park US, Su JJ, Ban KC, Qin L, Lee EH, Lee YI.
    Gene; 2000 Jun 13; 251(1):73-80. PubMed ID: 10863098
    [Abstract] [Full Text] [Related]

  • 20. Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis.
    Edamoto Y, Hara A, Biernat W, Terracciano L, Cathomas G, Riehle HM, Matsuda M, Fujii H, Scoazec JY, Ohgaki H.
    Int J Cancer; 2003 Sep 01; 106(3):334-41. PubMed ID: 12845670
    [Abstract] [Full Text] [Related]

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