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Journal Abstract Search

127 related items for PubMed ID: 30625324

  • 1. The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer.
    Zhu Q, Fang L, Heuberger J, Kranz A, Schipper J, Scheckenbach K, Vidal RO, Sunaga-Franze DY, Müller M, Wulf-Goldenberg A, Sauer S, Birchmeier W.
    Cell Rep; 2019 Jan 08; 26(2):415-428.e5. PubMed ID: 30625324
    [Abstract] [Full Text] [Related]

  • 2. Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours.
    Wend P, Fang L, Zhu Q, Schipper JH, Loddenkemper C, Kosel F, Brinkmann V, Eckert K, Hindersin S, Holland JD, Lehr S, Kahn M, Ziebold U, Birchmeier W.
    EMBO J; 2013 Jul 17; 32(14):1977-89. PubMed ID: 23736260
    [Abstract] [Full Text] [Related]

  • 3. The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
    Grinat J, Heuberger J, Vidal RO, Goveas N, Kosel F, Berenguer-Llergo A, Kranz A, Wulf-Goldenberg A, Behrens D, Melcher B, Sauer S, Vieth M, Batlle E, Stewart AF, Birchmeier W.
    Nat Commun; 2020 Dec 21; 11(1):6422. PubMed ID: 33349639
    [Abstract] [Full Text] [Related]

  • 4. miR-193a targets MLL1 mRNA and drastically decreases MLL1 protein production: Ectopic expression of the miRNA aberrantly lowers H3K4me3 content of the chromatin and hampers cell proliferation and viability.
    Sengupta D, Deb M, Kar S, Parbin S, Pradhan N, Patra SK.
    Gene; 2019 Jul 15; 705():22-35. PubMed ID: 31005612
    [Abstract] [Full Text] [Related]

  • 5. The STAT4/MLL1 Epigenetic Axis Regulates the Antimicrobial Functions of Murine Macrophages.
    Carson WF, Cavassani KA, Soares EM, Hirai S, Kittan NA, Schaller MA, Scola MM, Joshi A, Matsukawa A, Aronoff DM, Johnson CN, Dou Y, Gallagher KA, Kunkel SL.
    J Immunol; 2017 Sep 01; 199(5):1865-1874. PubMed ID: 28733487
    [Abstract] [Full Text] [Related]

  • 6. Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.
    Zhou C, Zhang Y, Dai J, Zhou M, Liu M, Wang Y, Chen XZ, Tang J.
    Sci Rep; 2016 Feb 23; 6():22066. PubMed ID: 26902498
    [Abstract] [Full Text] [Related]

  • 7. Break the loop, escape the cycle?
    van Amerongen R, Berns A.
    EMBO J; 2013 Jul 17; 32(14):1967-9. PubMed ID: 23749211
    [Abstract] [Full Text] [Related]

  • 8. Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.
    Cao F, Townsend EC, Karatas H, Xu J, Li L, Lee S, Liu L, Chen Y, Ouillette P, Zhu J, Hess JL, Atadja P, Lei M, Qin ZS, Malek S, Wang S, Dou Y.
    Mol Cell; 2014 Jan 23; 53(2):247-61. PubMed ID: 24389101
    [Abstract] [Full Text] [Related]

  • 9. Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex.
    Weirich S, Kudithipudi S, Jeltsch A.
    Mol Oncol; 2017 Apr 23; 11(4):373-387. PubMed ID: 28182322
    [Abstract] [Full Text] [Related]

  • 10. Decreased mixed lineage leukemia 1 is involved in endometriosis-related infertility.
    Wen X, Xiong Y, Liu H, Geng T, Jin L, Zhang M, Ma L, Zhang Y.
    J Mol Endocrinol; 2021 Jan 23; 66(1):45-57. PubMed ID: 33151904
    [Abstract] [Full Text] [Related]

  • 11. Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk.
    Wang Q, Trevino LS, Wong RL, Medvedovic M, Chen J, Ho SM, Shen J, Foulds CE, Coarfa C, O'Malley BW, Shilatifard A, Walker CL.
    Mol Endocrinol; 2016 Aug 23; 30(8):856-71. PubMed ID: 27219490
    [Abstract] [Full Text] [Related]

  • 12. The histone lysine methyltransferase MLL1 regulates the activation and functional specialization of regulatory T cells.
    Wang T, Guo J, Liping Li, Jin Q, Zhang F, Hou B, Zhang Y, Zhou X.
    Cell Rep; 2024 May 28; 43(5):114222. PubMed ID: 38735046
    [Abstract] [Full Text] [Related]

  • 13. Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes.
    Wiersma M, Bussiere M, Halsall JA, Turan N, Slany R, Turner BM, Nightingale KP.
    Epigenetics Chromatin; 2016 May 28; 9():52. PubMed ID: 27895715
    [Abstract] [Full Text] [Related]

  • 14. Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.
    Denissov S, Hofemeister H, Marks H, Kranz A, Ciotta G, Singh S, Anastassiadis K, Stunnenberg HG, Stewart AF.
    Development; 2014 Feb 28; 141(3):526-37. PubMed ID: 24423662
    [Abstract] [Full Text] [Related]

  • 15. MLL1 is required for maintenance of intestinal stem cells.
    Goveas N, Waskow C, Arndt K, Heuberger J, Zhang Q, Alexopoulou D, Dahl A, Birchmeier W, Anastassiadis K, Stewart AF, Kranz A.
    PLoS Genet; 2021 Dec 28; 17(12):e1009250. PubMed ID: 34860830
    [Abstract] [Full Text] [Related]

  • 16. The Histone Methyltransferase MLL1 Directs Macrophage-Mediated Inflammation in Wound Healing and Is Altered in a Murine Model of Obesity and Type 2 Diabetes.
    Kimball AS, Joshi A, Carson WF, Boniakowski AE, Schaller M, Allen R, Bermick J, Davis FM, Henke PK, Burant CF, Kunkel SL, Gallagher KA.
    Diabetes; 2017 Sep 28; 66(9):2459-2471. PubMed ID: 28663191
    [Abstract] [Full Text] [Related]

  • 17. MLL1/WDR5 complex in leukemogenesis and epigenetic regulation.
    Wu M, Shu HB.
    Chin J Cancer; 2011 Apr 28; 30(4):240-6. PubMed ID: 21439245
    [Abstract] [Full Text] [Related]

  • 18. High-affinity small molecular blockers of mixed lineage leukemia 1 (MLL1)-WDR5 interaction inhibit MLL1 complex H3K4 methyltransferase activity.
    Li DD, Chen WL, Wang ZH, Xie YY, Xu XL, Jiang ZY, Zhang XJ, You QD, Guo XK.
    Eur J Med Chem; 2016 Nov 29; 124():480-489. PubMed ID: 27598236
    [Abstract] [Full Text] [Related]

  • 19. MLL1, a H3K4 methyltransferase, regulates the TNFα-stimulated activation of genes downstream of NF-κB.
    Wang X, Zhu K, Li S, Liao Y, Du R, Zhang X, Shu HB, Guo AY, Li L, Wu M.
    J Cell Sci; 2012 Sep 01; 125(Pt 17):4058-66. PubMed ID: 22623725
    [Abstract] [Full Text] [Related]

  • 20. Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes.
    Ayoub A, Park SH, Lee YT, Cho US, Dou Y.
    Biochemistry; 2022 Jan 04; 61(1):1-9. PubMed ID: 34928138
    [Abstract] [Full Text] [Related]

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