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Journal Abstract Search

159 related items for PubMed ID: 30643209

  • 1. CP-25 reverses prostaglandin E4 receptor desensitization-induced fibroblast-like synoviocyte dysfunction via the G protein-coupled receptor kinase 2 in autoimmune arthritis.
    Jia XY, Chang Y, Wei F, Dai X, Wu YJ, Sun XJ, Xu S, Wu HX, Wang C, Yang XZ, Wei W.
    Acta Pharmacol Sin; 2019 Aug; 40(8):1029-1039. PubMed ID: 30643209
    [Abstract] [Full Text] [Related]

  • 2. CP-25 inhibits PGE2-induced angiogenesis by down-regulating EP4/AC/cAMP/PKA-mediated GRK2 translocation.
    Han CC, Liu Q, Zhang Y, Li YF, Cui DQ, Luo TT, Zhang YW, Wang XM, Wang C, Ma Y, Wei W.
    Clin Sci (Lond); 2020 Feb 14; 134(3):331-347. PubMed ID: 31967309
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  • 5. Targeted inhibition of GRK2 kinase domain by CP-25 to reverse fibroblast-like synoviocytes dysfunction and improve collagen-induced arthritis in rats.
    Han C, Li Y, Zhang Y, Wang Y, Cui D, Luo T, Zhang Y, Liu Q, Li H, Wang C, Xu D, Ma Y, Wei W.
    Acta Pharm Sin B; 2021 Jul 14; 11(7):1835-1852. PubMed ID: 34386323
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  • 7. Regulatory effects of paeoniflorin-6'-O-benzene sulfonate (CP-25) on dendritic cells maturation and activation via PGE2-EP4 signaling in adjuvant-induced arthritic rats.
    Jia XY, Chang Y, Sun XJ, Wei F, Wu YJ, Dai X, Xu S, Wu HX, Wang C, Yang XZ, Wei W.
    Inflammopharmacology; 2019 Oct 14; 27(5):997-1010. PubMed ID: 30771056
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  • 8. GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice.
    Yang X, Li S, Zhao Y, Li S, Zhao T, Tai Y, Zhang B, Wang X, Wang C, Chen J, Wang Q, Zhang L, Xu D, Chang Y, Wei W.
    Cells; 2019 Dec 08; 8(12):. PubMed ID: 31818003
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  • 11. The ROS/GRK2/HIF-1α/NLRP3 Pathway Mediates Pyroptosis of Fibroblast-Like Synoviocytes and the Regulation of Monomer Derivatives of Paeoniflorin.
    Hong Z, Zhang X, Zhang T, Hu L, Liu R, Wang P, Wang H, Yu Q, Mei D, Xue Z, Zhang F, Zhang L.
    Oxid Med Cell Longev; 2022 Dec 08; 2022():4566851. PubMed ID: 35132350
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  • 12. Paeoniflorin-6'-O-benzene sulfonate down-regulates CXCR4-Gβγ-PI3K/AKT mediated migration in fibroblast-like synoviocytes of rheumatoid arthritis by inhibiting GRK2 translocation.
    Wang DD, Jiang MY, Wang W, Zhou WJ, Zhang YW, Yang M, Chen JY, Wei W.
    Biochem Biophys Res Commun; 2020 Jun 04; 526(3):805-812. PubMed ID: 32268958
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  • 13. Paeoniflorin inhibits function of synoviocytes pretreated by rIL-1α and regulates EP4 receptor expression.
    Chang Y, Zhang L, Wang C, Jia XY, Wei W.
    J Ethnopharmacol; 2011 Oct 11; 137(3):1275-82. PubMed ID: 21840386
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  • 14. Paeoniflorin inhibits proliferation of fibroblast-like synoviocytes through suppressing G-protein-coupled receptor kinase 2.
    Chen JY, Wu HX, Chen Y, Zhang LL, Wang QT, Sun WY, Wei W.
    Planta Med; 2012 May 11; 78(7):665-71. PubMed ID: 22411721
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  • 15. CP-25 exerts anti-angiogenic effects on a rat model of adjuvant-induced arthritis by promoting GRK2-induced downregulation of CXCR4-ERK1/2 signaling in endothelial cells.
    Zhang M, Gao M, Chen J, Song L, Wei W.
    Mol Med Rep; 2019 Dec 11; 20(6):4831-4842. PubMed ID: 31661133
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  • 16. CP-25 attenuates the inflammatory response of fibroblast-like synoviocytes co-cultured with BAFF-activated CD4(+) T cells.
    Jia X, Wei F, Sun X, Chang Y, Xu S, Yang X, Wang C, Wei W.
    J Ethnopharmacol; 2016 Aug 02; 189():194-201. PubMed ID: 27196292
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  • 17. Regulation of CP-25 on P-glycoprotein in synoviocytes of rats with adjuvant arthritis.
    Tang H, Wu YJ, Xiao F, Wang B, Asenso J, Wang Y, Sun W, Wang C, Wei W.
    Biomed Pharmacother; 2019 Nov 02; 119():109432. PubMed ID: 31521892
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  • 18. CP-25 inhibits the hyperactivation of rheumatic synoviocytes by suppressing the switch in Gαs-Gαi coupling to the β2-adrenergic receptor.
    Ge M, Wu L, He F, Tai Y, Fang R, Han D, Guo P, Liu H, Hu Y, Xu S, Wei W, Wang Q.
    Cell Commun Signal; 2023 Nov 30; 21(1):346. PubMed ID: 38037039
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  • 19. Exploring and characterizing a novel combination of paeoniflorin and talatizidine for the treatment of rheumatoid arthritis.
    Mao X, Li W, Chen W, Li Y, Wang Q, Wang X, Pi Z, Wang D, Xu H, Guo Q, Wu S, Cheng W, Zhang Y, Lin N.
    Pharmacol Res; 2020 Mar 30; 153():104658. PubMed ID: 32001347
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