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390 related items for PubMed ID: 30661182

  • 1. Bag-1 silencing enhanced chemotherapeutic drug-induced apoptosis in MCF-7 breast cancer cells affecting PI3K/Akt/mTOR and MAPK signaling pathways.
    Kilbas PO, Akcay IM, Doganay GD, Arisan ED.
    Mol Biol Rep; 2019 Feb; 46(1):847-860. PubMed ID: 30661182
    [Abstract] [Full Text] [Related]

  • 2. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP, Yang YX, Liu QL, Pan ST, He ZX, Zhang X, Yang T, Chen XW, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Feb; 9():1627-52. PubMed ID: 25834401
    [Abstract] [Full Text] [Related]

  • 3. Bag-1 promotes cell survival through c-Myc-mediated ODC upregulation that is not preferred under apoptotic stimuli in MCF-7 cells.
    Ozfiliz P, Kizilboga T, Demir S, Alkurt G, Palavan-Unsal N, Arisan ED, Dinler-Doganay G.
    Cell Biochem Funct; 2015 Jul; 33(5):293-307. PubMed ID: 26178413
    [Abstract] [Full Text] [Related]

  • 4. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Jul; 9():1555-84. PubMed ID: 25792811
    [Abstract] [Full Text] [Related]

  • 5. Tunicamycin potentiates paclitaxel-induced apoptosis through inhibition of PI3K/AKT and MAPK pathways in breast cancer.
    Huang S, Wang D, Zhang S, Huang X, Wang D, Ijaz M, Shi Y.
    Cancer Chemother Pharmacol; 2017 Oct; 80(4):685-696. PubMed ID: 28779263
    [Abstract] [Full Text] [Related]

  • 6. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST, Qin Y, Zhou ZW, He ZX, Zhang X, Yang T, Yang YX, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Oct; 9():1601-26. PubMed ID: 25834400
    [Abstract] [Full Text] [Related]

  • 7. Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity.
    Menendez JA, Vellon L, Colomer R, Lupu R.
    Int J Cancer; 2005 May 20; 115(1):19-35. PubMed ID: 15657900
    [Abstract] [Full Text] [Related]

  • 8. Effects of endoplasmic reticulum stress on the autophagy, apoptosis, and chemotherapy resistance of human breast cancer cells by regulating the PI3K/AKT/mTOR signaling pathway.
    Zhong JT, Yu J, Wang HJ, Shi Y, Zhao TS, He BX, Qiao B, Feng ZW.
    Tumour Biol; 2017 May 20; 39(5):1010428317697562. PubMed ID: 28459209
    [Abstract] [Full Text] [Related]

  • 9. Regulation of the cell cycle and PI3K/Akt/mTOR signaling pathway by tanshinone I in human breast cancer cell lines.
    Wang L, Wu J, Lu J, Ma R, Sun D, Tang J.
    Mol Med Rep; 2015 Feb 20; 11(2):931-9. PubMed ID: 25355053
    [Abstract] [Full Text] [Related]

  • 10. Bag-1 stimulates Bad phosphorylation through activation of Akt and Raf kinases to mediate cell survival in breast cancer.
    Kizilboga T, Baskale EA, Yildiz J, Akcay IM, Zemheri E, Can ND, Ozden C, Demir S, Ezberci F, Dinler-Doganay G.
    BMC Cancer; 2019 Dec 28; 19(1):1254. PubMed ID: 31883527
    [Abstract] [Full Text] [Related]

  • 11. The phosphatidylinositol 3-kinase/AKT signal transduction pathway plays a critical role in the expression of p21WAF1/CIP1/SDI1 induced by cisplatin and paclitaxel.
    Mitsuuchi Y, Johnson SW, Selvakumaran M, Williams SJ, Hamilton TC, Testa JR.
    Cancer Res; 2000 Oct 01; 60(19):5390-4. PubMed ID: 11034077
    [Abstract] [Full Text] [Related]

  • 12. Silencing PCMT1 enhances the sensitivity of breast cancer cells to paclitaxel through the PI3K/Akt/STMN1 pathway.
    Zhang K, Li JY, Li K.
    Chem Biol Drug Des; 2024 Jun 01; 103(6):e14559. PubMed ID: 38853025
    [Abstract] [Full Text] [Related]

  • 13. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
    Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.
    Eur J Pharmacol; 2007 Jun 01; 563(1-3):49-60. PubMed ID: 17341418
    [Abstract] [Full Text] [Related]

  • 14. Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways.
    Zhang L, Huo X, Liao Y, Yang F, Gao L, Cao L.
    Sci Rep; 2017 May 10; 7(1):1669. PubMed ID: 28490807
    [Abstract] [Full Text] [Related]

  • 15. Downregulation of BAG‑1 in T47D cells promotes resistance to tamoxifen via activation of the PI3K/Akt/mTOR signaling pathway.
    Lu S, Du Y, Cui F, Feng X, Ma Y, Liu H.
    Oncol Rep; 2019 Mar 10; 41(3):1901-1910. PubMed ID: 30747221
    [Abstract] [Full Text] [Related]

  • 16. Inhibitory effects of everolimus in combination with paclitaxel on adriamycin-resistant breast cancer cell line MDA-MB-231.
    Xu T, Liu P, Li Q, Shi C, Wang X.
    Taiwan J Obstet Gynecol; 2020 Nov 10; 59(6):828-834. PubMed ID: 33218396
    [Abstract] [Full Text] [Related]

  • 17. Benzo[b]furan derivatives induces apoptosis by targeting the PI3K/Akt/mTOR signaling pathway in human breast cancer cells.
    Kamal A, Lakshma Nayak V, Nagesh N, Vishnuvardhan MV, Subba Reddy NV.
    Bioorg Chem; 2016 Jun 10; 66():124-31. PubMed ID: 27149364
    [Abstract] [Full Text] [Related]

  • 18. Magnoflorine improves sensitivity to doxorubicin (DOX) of breast cancer cells via inducing apoptosis and autophagy through AKT/mTOR and p38 signaling pathways.
    Wei T, Xiaojun X, Peilong C.
    Biomed Pharmacother; 2020 Jan 10; 121():109139. PubMed ID: 31707337
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of Autophagy Increases Proliferation Inhibition and Apoptosis Induced by the PI3K/mTOR Inhibitor NVP-BEZ235 in Breast Cancer Cells.
    Ji Y, Di W, Yang Q, Lu Z, Cai W, Wu J.
    Clin Lab; 2015 Jan 10; 61(8):1043-51. PubMed ID: 26427150
    [Abstract] [Full Text] [Related]

  • 20. Dual PI3K/mTOR inhibitor BEZ235 as a promising therapeutic strategy against paclitaxel-resistant gastric cancer via targeting PI3K/Akt/mTOR pathway.
    Chen D, Lin X, Zhang C, Liu Z, Chen Z, Li Z, Wang J, Li B, Hu Y, Dong B, Shen L, Ji J, Gao J, Zhang X.
    Cell Death Dis; 2018 Jan 26; 9(2):123. PubMed ID: 29374144
    [Abstract] [Full Text] [Related]

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