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199 related items for PubMed ID: 30685490

  • 1. Withaferin A-mediated apoptosis in breast cancer cells is associated with alterations in mitochondrial dynamics.
    Sehrawat A, Samanta SK, Hahm ER, St Croix C, Watkins S, Singh SV.
    Mitochondrion; 2019 Jul; 47():282-293. PubMed ID: 30685490
    [Abstract] [Full Text] [Related]

  • 2. Growth arrest by the antitumor steroidal lactone withaferin A in human breast cancer cells is associated with down-regulation and covalent binding at cysteine 303 of β-tubulin.
    Antony ML, Lee J, Hahm ER, Kim SH, Marcus AI, Kumari V, Ji X, Yang Z, Vowell CL, Wipf P, Uechi GT, Yates NA, Romero G, Sarkar SN, Singh SV.
    J Biol Chem; 2014 Jan 17; 289(3):1852-65. PubMed ID: 24297176
    [Abstract] [Full Text] [Related]

  • 3. Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species.
    Hahm ER, Moura MB, Kelley EE, Van Houten B, Shiva S, Singh SV.
    PLoS One; 2011 Jan 17; 6(8):e23354. PubMed ID: 21853114
    [Abstract] [Full Text] [Related]

  • 4. Withaferin A inhibits expression of ataxia telangiectasia and Rad3-related kinase and enhances sensitivity of human breast cancer cells to cisplatin.
    Hahm ER, Lee J, Abella T, Singh SV.
    Mol Carcinog; 2019 Nov 17; 58(11):2139-2148. PubMed ID: 31441116
    [Abstract] [Full Text] [Related]

  • 5. The Role of Forkhead Box Q1 Transcription Factor in Anticancer Effects of Withaferin A in Breast Cancer.
    Kim SH, Singh KB, Hahm ER, Singh SV.
    Cancer Prev Res (Phila); 2021 Apr 17; 14(4):421-432. PubMed ID: 33509807
    [Abstract] [Full Text] [Related]

  • 6. Dynamin-related protein 1-mediated mitochondrial fission contributes to IR-783-induced apoptosis in human breast cancer cells.
    Tang Q, Liu W, Zhang Q, Huang J, Hu C, Liu Y, Wang Q, Zhou M, Lai W, Sheng F, Li G, Zhang R.
    J Cell Mol Med; 2018 Sep 17; 22(9):4474-4485. PubMed ID: 29993201
    [Abstract] [Full Text] [Related]

  • 7. Withaferin A inhibits experimental epithelial-mesenchymal transition in MCF-10A cells and suppresses vimentin protein level in vivo in breast tumors.
    Lee J, Hahm ER, Marcus AI, Singh SV.
    Mol Carcinog; 2015 Jun 17; 54(6):417-29. PubMed ID: 24293234
    [Abstract] [Full Text] [Related]

  • 8. Withaferin A induces apoptosis by ROS-dependent mitochondrial dysfunction in human colorectal cancer cells.
    Xia S, Miao Y, Liu S.
    Biochem Biophys Res Commun; 2018 Sep 18; 503(4):2363-2369. PubMed ID: 29966656
    [Abstract] [Full Text] [Related]

  • 9. Withaferin a suppresses estrogen receptor-α expression in human breast cancer cells.
    Hahm ER, Lee J, Huang Y, Singh SV.
    Mol Carcinog; 2011 Aug 18; 50(8):614-24. PubMed ID: 21432907
    [Abstract] [Full Text] [Related]

  • 10. Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells.
    Lee J, Sehrawat A, Singh SV.
    Breast Cancer Res Treat; 2012 Nov 18; 136(1):45-56. PubMed ID: 22965833
    [Abstract] [Full Text] [Related]

  • 11. Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo.
    Stan SD, Hahm ER, Warin R, Singh SV.
    Cancer Res; 2008 Sep 15; 68(18):7661-9. PubMed ID: 18794155
    [Abstract] [Full Text] [Related]

  • 12. RNA-seq reveals novel cancer-selective and disease subtype-independent mechanistic targets of withaferin A in human breast cancer cells.
    Hahm ER, Kim SH, Singh KB, Singh SV.
    Mol Carcinog; 2021 Jan 15; 60(1):3-14. PubMed ID: 33150660
    [Abstract] [Full Text] [Related]

  • 13. Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells.
    Hahm ER, Lee J, Singh SV.
    Mol Carcinog; 2014 Nov 15; 53(11):907-16. PubMed ID: 24019090
    [Abstract] [Full Text] [Related]

  • 14. Autophagy fails to alter withaferin A-mediated lethality in human breast cancer cells.
    Hahm ER, Singh SV.
    Curr Cancer Drug Targets; 2013 Jul 15; 13(6):640-50. PubMed ID: 23607597
    [Abstract] [Full Text] [Related]

  • 15. Withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells.
    Lee J, Hahm ER, Singh SV.
    Carcinogenesis; 2010 Nov 15; 31(11):1991-8. PubMed ID: 20724373
    [Abstract] [Full Text] [Related]

  • 16. Peptidyl-prolyl cis/trans isomerase Pin1 regulates withaferin A-mediated cell cycle arrest in human breast cancer cells.
    Samanta SK, Lee J, Hahm ER, Singh SV.
    Mol Carcinog; 2018 Jul 15; 57(7):936-946. PubMed ID: 29603395
    [Abstract] [Full Text] [Related]

  • 17. Down-regulation of estrogen receptor-alpha and rearranged during transfection tyrosine kinase is associated with withaferin a-induced apoptosis in MCF-7 breast cancer cells.
    Zhang X, Mukerji R, Samadi AK, Cohen MS.
    BMC Complement Altern Med; 2011 Oct 06; 11():84. PubMed ID: 21978374
    [Abstract] [Full Text] [Related]

  • 18. Withaferin A Induces ROS-Mediated Paraptosis in Human Breast Cancer Cell-Lines MCF-7 and MDA-MB-231.
    Ghosh K, De S, Das S, Mukherjee S, Sengupta Bandyopadhyay S.
    PLoS One; 2016 Oct 06; 11(12):e0168488. PubMed ID: 28033383
    [Abstract] [Full Text] [Related]

  • 19. Withaferin A-induced apoptosis in human breast cancer cells is associated with suppression of inhibitor of apoptosis family protein expression.
    Hahm ER, Singh SV.
    Cancer Lett; 2013 Jun 28; 334(1):101-8. PubMed ID: 22935676
    [Abstract] [Full Text] [Related]

  • 20. Proteomic characterization of Withaferin A-targeted protein networks for the treatment of monoclonal myeloma gammopathies.
    Dom M, Offner F, Vanden Berghe W, Van Ostade X.
    J Proteomics; 2018 May 15; 179():17-29. PubMed ID: 29448055
    [Abstract] [Full Text] [Related]

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