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Journal Abstract Search


406 related items for PubMed ID: 30784099

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  • 4. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease.
    Oksenberg D, Dufu K, Patel MP, Chuang C, Li Z, Xu Q, Silva-Garcia A, Zhou C, Hutchaleelaha A, Patskovska L, Patskovsky Y, Almo SC, Sinha U, Metcalf BW, Archer DR.
    Br J Haematol; 2016 Oct; 175(1):141-53. PubMed ID: 27378309
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  • 11. VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditions.
    Abdulmalik O, Pagare PP, Huang B, Xu GG, Ghatge MS, Xu X, Chen Q, Anabaraonye N, Musayev FN, Omar AM, Venitz J, Zhang Y, Safo MK.
    Sci Rep; 2020 Nov 20; 10(1):20277. PubMed ID: 33219275
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  • 15. Substituted benzaldehydes (12C79 and 589C80) that stabilize oxyhaemoglobin also protect sickle cells against calcium-mediated dehydration.
    Stone PC, Nash GB, Stuart J.
    Br J Haematol; 1992 Jul 20; 81(3):419-23. PubMed ID: 1390217
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  • 16. GBT440 improves red blood cell deformability and reduces viscosity of sickle cell blood under deoxygenated conditions.
    Dufu K, Patel M, Oksenberg D, Cabrales P.
    Clin Hemorheol Microcirc; 2018 Jul 20; 70(1):95-105. PubMed ID: 29660913
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  • 19. Nitric oxide reduces sickle hemoglobin polymerization: potential role of nitric oxide-induced charge alteration in depolymerization.
    Ikuta T, Thatte HS, Tang JX, Mukerji I, Knee K, Bridges KR, Wang S, Montero-Huerta P, Joshi RM, Head CA.
    Arch Biochem Biophys; 2011 Jun 01; 510(1):53-61. PubMed ID: 21457702
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  • 20. Effects of hemoglobin concentration on deformability of individual sickle cells after deoxygenation.
    Itoh T, Chien S, Usami S.
    Blood; 1995 Apr 15; 85(8):2245-53. PubMed ID: 7718897
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