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PUBMED FOR HANDHELDS

Journal Abstract Search


242 related items for PubMed ID: 30785020

  • 1. Novel 2,4-disubstituted quinazolines as cytotoxic agents and JAK2 inhibitors: Synthesis, in vitro evaluation and molecular dynamics studies.
    Jyothi Buggana S, Paturi MC, Perka H, Gade DR, Vvs RP.
    Comput Biol Chem; 2019 Apr; 79():110-118. PubMed ID: 30785020
    [Abstract] [Full Text] [Related]

  • 2. 2,4-Disubstituted quinazolines targeting breast cancer cells via EGFR-PI3K.
    Li ED, Lin Q, Meng YQ, Zhang LY, Song PP, Li N, Xin JC, Yang P, Bao CN, Zhang DQ, Zhang Y, Wang JK, Zhang QR, Liu HM.
    Eur J Med Chem; 2019 Jun 15; 172():36-47. PubMed ID: 30939352
    [Abstract] [Full Text] [Related]

  • 3. Virtual screening and synthesis of quinazolines as novel JAK2 inhibitors.
    Yang SH, Khadka DB, Cho SH, Ju HK, Lee KY, Han HJ, Lee KT, Cho WJ.
    Bioorg Med Chem; 2011 Jan 15; 19(2):968-77. PubMed ID: 21185195
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, Molecular Modeling and Biological Evaluation of 4-Alkoxyquinazoline Derivatives as Novel Inhibitors of VEGFR2.
    Lu L, Zhao TT, Liu TB, Sun WX, Xu C, Li DD, Zhu HL.
    Chem Pharm Bull (Tokyo); 2016 Nov 01; 64(11):1570-1575. PubMed ID: 27568484
    [Abstract] [Full Text] [Related]

  • 5. Development of a series of novel 4-anlinoquinazoline derivatives possessing quinazoline skeleton: Design, synthesis, EGFR kinase inhibitory efficacy, and evaluation of anticancer activities in vitro.
    Chang J, Ren H, Zhao M, Chong Y, Zhao W, He Y, Zhao Y, Zhang H, Qi C.
    Eur J Med Chem; 2017 Sep 29; 138():669-688. PubMed ID: 28711702
    [Abstract] [Full Text] [Related]

  • 6. Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2.
    Alkahtani HM, Abdalla AN, Obaidullah AJ, Alanazi MM, Almehizia AA, Alanazi MG, Ahmed AY, Alwassil OI, Darwish HW, Abdel-Aziz AA, El-Azab AS.
    Bioorg Chem; 2020 Jan 29; 95():103461. PubMed ID: 31838290
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis and biological evaluation of novel 2,4-disubstituted quinazoline derivatives targeting H1975 cells via EGFR-PI3K signaling pathway.
    Wang Z, Liu L, Dai H, Si X, Zhang L, Li E, Yang Z, Chao G, Zheng J, Ke Y, Lihong S, Zhang Q, Liu H.
    Bioorg Med Chem; 2021 Aug 01; 43():116265. PubMed ID: 34192644
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis, anti-tumor activity, and molecular modeling of quinazoline and pyrido[2,3-d]pyrimidine derivatives targeting epidermal growth factor receptor.
    Hou J, Wan S, Wang G, Zhang T, Li Z, Tian Y, Yu Y, Wu X, Zhang J.
    Eur J Med Chem; 2016 Aug 08; 118():276-89. PubMed ID: 27132165
    [Abstract] [Full Text] [Related]

  • 9. Discovery and rational design of 2-aminopyrimidine-based derivatives targeting Janus kinase 2 (JAK2) and FMS-like tyrosine kinase 3 (FLT3).
    Li Y, Wang P, Chen C, Ye T, Han Y, Hou Y, Liu Y, Gong P, Qin M, Zhao Y.
    Bioorg Chem; 2020 Nov 08; 104():104361. PubMed ID: 33142418
    [Abstract] [Full Text] [Related]

  • 10. Benzo[g]quinazolin-based scaffold derivatives as dual EGFR/HER2 inhibitors.
    Ghorab MM, Alsaid MS, Soliman AM, Al-Mishari AA.
    J Enzyme Inhib Med Chem; 2018 Dec 08; 33(1):67-73. PubMed ID: 29098904
    [Abstract] [Full Text] [Related]

  • 11. Quinazoline-based multi-tyrosine kinase inhibitors: synthesis, modeling, antitumor and antiangiogenic properties.
    Conconi MT, Marzaro G, Urbani L, Zanusso I, Di Liddo R, Castagliuolo I, Brun P, Tonus F, Ferrarese A, Guiotto A, Chilin A.
    Eur J Med Chem; 2013 Sep 08; 67():373-83. PubMed ID: 23900004
    [Abstract] [Full Text] [Related]

  • 12. Novel morpholin-3-one fused quinazoline derivatives as EGFR tyrosine kinase inhibitors.
    Qin X, Lv Y, Liu P, Li Z, Hu L, Zeng C, Yang L.
    Bioorg Med Chem Lett; 2016 Mar 15; 26(6):1571-1575. PubMed ID: 26879314
    [Abstract] [Full Text] [Related]

  • 13. Pyrrole-3-carboxamides as potent and selective JAK2 inhibitors.
    Brasca MG, Nesi M, Avanzi N, Ballinari D, Bandiera T, Bertrand J, Bindi S, Canevari G, Carenzi D, Casero D, Ceriani L, Ciomei M, Cirla A, Colombo M, Cribioli S, Cristiani C, Della Vedova F, Fachin G, Fasolini M, Felder ER, Galvani A, Isacchi A, Mirizzi D, Motto I, Panzeri A, Pesenti E, Vianello P, Gnocchi P, Donati D.
    Bioorg Med Chem; 2014 Sep 01; 22(17):4998-5012. PubMed ID: 25009002
    [Abstract] [Full Text] [Related]

  • 14. Discovery of 6-substituted 4-anilinoquinazolines with dioxygenated rings as novel EGFR tyrosine kinase inhibitors.
    Li DD, Fang F, Li JR, Du QR, Sun J, Gong HB, Zhu HL.
    Bioorg Med Chem Lett; 2012 Sep 15; 22(18):5870-5. PubMed ID: 22901387
    [Abstract] [Full Text] [Related]

  • 15. The Effect of a Newly Synthesized Ferrocene Derivative against MCF-7 Breast Cancer Cells and Spheroid Stem Cells through ROS Production and Inhibition of JAK2/STAT3 Signaling Pathway.
    Nourbakhsh M, Farzaneh S, Taghikhani A, Zarghi A, Noori S.
    Anticancer Agents Med Chem; 2020 Sep 15; 20(7):875-886. PubMed ID: 31893999
    [Abstract] [Full Text] [Related]

  • 16. Facile and efficient synthesis and biological evaluation of 4-anilinoquinazoline derivatives as EGFR inhibitors.
    Wang Z, Wu X, Wang L, Zhang J, Liu J, Song Z, Tang Z.
    Bioorg Med Chem Lett; 2016 Jun 01; 26(11):2589-93. PubMed ID: 27118497
    [Abstract] [Full Text] [Related]

  • 17. Molecular modelling and synthesis of quinazoline-based compounds as potential antiproliferative agents.
    Yassen AS, Elshihawy HE, Said MM, Abouzid KA.
    Chem Pharm Bull (Tokyo); 2014 Jun 01; 62(5):454-66. PubMed ID: 24789927
    [Abstract] [Full Text] [Related]

  • 18. Novel 4-aminoquinazoline derivatives induce growth inhibition, cell cycle arrest and apoptosis via PI3Kα inhibition.
    Fan YH, Ding HW, Liu DD, Song HR, Xu YN, Wang J.
    Bioorg Med Chem; 2018 May 01; 26(8):1675-1685. PubMed ID: 29475582
    [Abstract] [Full Text] [Related]

  • 19. Compounds Consisting of Quinazoline, Ibuprofen, and Amino Acids with Cytotoxic and Anti-Inflammatory Effects.
    Garduño-Villavicencio LR, Martínez-Ortega U, Ortiz-Sánchez E, Tinajero-Rodríguez JM, Hernández-Luis F.
    ChemMedChem; 2024 May 17; 19(10):e202300651. PubMed ID: 38354370
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis, antiproliferative activity and docking studies of quinazoline derivatives bearing 2,3-dihydro-indole or 1,2,3,4-tetrahydroquinoline as potential EGFR inhibitors.
    OuYang Y, Zou W, Peng L, Yang Z, Tang Q, Chen M, Jia S, Zhang H, Lan Z, Zheng P, Zhu W.
    Eur J Med Chem; 2018 Jun 25; 154():29-43. PubMed ID: 29775935
    [Abstract] [Full Text] [Related]


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