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127 related items for PubMed ID: 30785507

  • 1. The effect of hirudin on antagonisting thrombin induced apoptosis of human microvascular endothelial cells1.
    Zhu J, Pan X, Lin B, Lin G, Pradhan R, Long F, Yin G.
    Acta Cir Bras; 2019 Feb 14; 34(1):e20190010000006. PubMed ID: 30785507
    [Abstract] [Full Text] [Related]

  • 2. [Effect of natural hirudin on angiogenesis of human microvascular endothelial cells].
    Lin G, Lin B, Zhu J, Pan X, Yin G.
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2018 Dec 15; 32(12):1586-1591. PubMed ID: 30569688
    [Abstract] [Full Text] [Related]

  • 3. The thrombin antagonist hirudin fails to inhibit endotoxin-induced leukocyte/endothelial cell interaction and microvascular perfusion failure.
    Hoffmann JN, Vollmar B, Inthorn D, Schildberg FW, Menger MD.
    Shock; 2000 Nov 15; 14(5):528-34. PubMed ID: 11092685
    [Abstract] [Full Text] [Related]

  • 4. Antithrombin effects of native and recombinant hirudins.
    Markwardt F, Stürzebecher J, Glusa E.
    Biomed Biochim Acta; 1990 Nov 15; 49(5):399-404. PubMed ID: 2271010
    [Abstract] [Full Text] [Related]

  • 5. [Effect of AG490 on JAK2/STAT3 signaling pathway in human retinoblastoma HXO-RB44 cell lines].
    Xu B, Chen X, Tan J, Xu X.
    Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2018 Oct 28; 43(10):1061-1067. PubMed ID: 30523225
    [Abstract] [Full Text] [Related]

  • 6. JAK2 tyrosine kinase inhibitor AG490 suppresses cell growth and invasion of gallbladder cancer cells via inhibition of JAK2/STAT3 signaling.
    Fu LX, Lian QW, Pan JD, Xu ZL, Zhou TM, Ye B.
    J Biol Regul Homeost Agents; 2017 Oct 28; 31(1):51-58. PubMed ID: 28337870
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of thrombin during reperfusion improves immediate postischemic myocardial function and modulates apoptosis in a porcine model of cardiopulmonary bypass.
    Jormalainen M, Vento AE, Lukkarinen H, Kääpä P, Kytö V, Lauronen J, Paavonen T, Suojaranta-Ylinen R, Petäjä J.
    J Cardiothorac Vasc Anesth; 2007 Apr 28; 21(2):224-31. PubMed ID: 17418736
    [Abstract] [Full Text] [Related]

  • 8. Electrostatic steering and ionic tethering in the formation of thrombin-hirudin complexes: the role of the thrombin anion-binding exosite-I.
    Myles T, Le Bonniec BF, Betz A, Stone SR.
    Biochemistry; 2001 Apr 24; 40(16):4972-9. PubMed ID: 11305913
    [Abstract] [Full Text] [Related]

  • 9. Recombinant hirudin suppresses the viability, adhesion, migration and invasion of Hep-2 human laryngeal cancer cells.
    Lu Q, Lv M, Xu E, Shao F, Feng Y, Yang J, Shi L.
    Oncol Rep; 2015 Mar 24; 33(3):1358-64. PubMed ID: 25592110
    [Abstract] [Full Text] [Related]

  • 10. Comparison of hirudin and hirudin PA C-terminal fragments and related analogs as antithrombin agents.
    Krstenansky JL, Owen TJ, Yates MT, Mao SJ.
    Thromb Res; 1988 Oct 15; 52(2):137-41. PubMed ID: 3194888
    [Abstract] [Full Text] [Related]

  • 11. Effects of hirudin (thrombin specific inhibitor) in zebrafish embryos: a developmental role for thrombin.
    Jagadeeswaran P, Liu YC, Eddy CA.
    Blood Cells Mol Dis; 1997 Dec 15; 23(3):410-4. PubMed ID: 9446755
    [Abstract] [Full Text] [Related]

  • 12. Expression of hirudin fusion proteins in mammalian cells: a strategy for prevention of intravascular thrombosis.
    Riesbeck K, Chen D, Kemball-Cook G, McVey JH, George AJ, Tuddenham EG, Dorling A, Lechler RI.
    Circulation; 1998 Dec 15; 98(24):2744-52. PubMed ID: 9851962
    [Abstract] [Full Text] [Related]

  • 13. Involvement of nuclear JAK2 signaling in AG490-induced apoptosis of gastric cancer cells.
    Qian C, Wang J, Yao J, Wang L, Xue M, Liu W, Si J.
    Anat Rec (Hoboken); 2013 Dec 15; 296(12):1865-73. PubMed ID: 24151255
    [Abstract] [Full Text] [Related]

  • 14. Direct thrombin inhibitors for treatment of arterial thrombosis: potential differences between bivalirudin and hirudin.
    Bates SM, Weitz JI.
    Am J Cardiol; 1998 Oct 22; 82(8B):12P-18P. PubMed ID: 9809887
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of the JAK2/STAT3/SOSC1 Signaling Pathway Improves Secretion Function of Vascular Endothelial Cells in a Rat Model of Pregnancy-Induced Hypertension.
    Luo JY, Fu D, Wu YQ, Gao Y.
    Cell Physiol Biochem; 2016 Oct 22; 40(3-4):527-537. PubMed ID: 27889763
    [Abstract] [Full Text] [Related]

  • 16. Hirudin ameliorates immunoglobulin A nephropathy by inhibition of fibrosis and inflammatory response.
    Deng F, Zhang J, Li Y, Wang W, Hong D, Li G, Feng J.
    Ren Fail; 2019 Nov 22; 41(1):104-112. PubMed ID: 30880546
    [Abstract] [Full Text] [Related]

  • 17. Comparative studies on the anticoagulant and protease generation inhibitory actions of newly developed site-directed thrombin inhibitory drugs. Efegatran, argatroban, hirulog, and hirudin.
    Callas DD, Hoppensteadt D, Fareed J.
    Semin Thromb Hemost; 1995 Nov 22; 21(2):177-83. PubMed ID: 7660140
    [Abstract] [Full Text] [Related]

  • 18. [(*)AG490 could suppress bone marrow mesenchymal stem cells migration, mineralization and bone defect healing via inhibiting Jak2-STAT3 pathway].
    Yu X, Wan QL, Li Z, Li ZB.
    Zhonghua Kou Qiang Yi Xue Za Zhi; 2018 May 09; 53(5):293-300. PubMed ID: 29972985
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of JAK2/STAT3 Signaling Pathway Suppresses Proliferation of Burkitt's Lymphoma Raji Cells via Cell Cycle Progression, Apoptosis, and Oxidative Stress by Modulating HSP70.
    Xu NW, Chen Y, Liu W, Chen YJ, Fan ZM, Liu M, Li LJ.
    Med Sci Monit; 2018 Sep 08; 24():6255-6263. PubMed ID: 30194286
    [Abstract] [Full Text] [Related]

  • 20. Comparison of the effects of heparin and hirudin on thrombin binding to the normal and the de-endothelialized rabbit aorta in vitro.
    Hatton MW, Moar SL.
    Thromb Haemost; 1991 Aug 01; 66(2):208-12. PubMed ID: 1771613
    [Abstract] [Full Text] [Related]

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