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Journal Abstract Search

635 related items for PubMed ID: 30793584

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  • 2. β-site amyloid precursor protein-cleaving enzyme 1(BACE1) inhibitor treatment induces Aβ5-X peptides through alternative amyloid precursor protein cleavage.
    Portelius E, Dean RA, Andreasson U, Mattsson N, Westerlund A, Olsson M, Demattos RB, Racke MM, Zetterberg H, May PC, Blennow K.
    Alzheimers Res Ther; 2014; 6(5-8):75. PubMed ID: 25404952
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  • 4. Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism.
    Cohen SI, Linse S, Luheshi LM, Hellstrand E, White DA, Rajah L, Otzen DE, Vendruscolo M, Dobson CM, Knowles TP.
    Proc Natl Acad Sci U S A; 2013 Jun 11; 110(24):9758-63. PubMed ID: 23703910
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  • 7. Inhibition of BACE1 affected both its Aβ producing and degrading activities and increased Aβ42 and Aβ40 levels at high-level BACE1 expression.
    Ulku I, Leung R, Herre F, Walther L, Shobo A, Saftig P, Hancock MA, Liebsch F, Multhaup G.
    J Biol Chem; 2024 Aug 11; 300(8):107510. PubMed ID: 38944120
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  • 11. Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons.
    Lee EB, Skovronsky DM, Abtahian F, Doms RW, Lee VM.
    J Biol Chem; 2003 Feb 14; 278(7):4458-66. PubMed ID: 12480937
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  • 13. N-Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42.
    Szczepankiewicz O, Linse B, Meisl G, Thulin E, Frohm B, Sala Frigerio C, Colvin MT, Jacavone AC, Griffin RG, Knowles T, Walsh DM, Linse S.
    J Am Chem Soc; 2015 Nov 25; 137(46):14673-85. PubMed ID: 26535489
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  • 15. BACE1: the beta-secretase enzyme in Alzheimer's disease.
    Vassar R.
    J Mol Neurosci; 2004 Nov 25; 23(1-2):105-14. PubMed ID: 15126696
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  • 16. The beta-secretase, BACE: a prime drug target for Alzheimer's disease.
    Vassar R.
    J Mol Neurosci; 2001 Oct 25; 17(2):157-70. PubMed ID: 11816789
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  • 17. Structural and molecular insights into tacrine-benzofuran hybrid induced inhibition of amyloid-β peptide aggregation and BACE1 activity.
    Kaur R, Narang SS, Singh P, Goyal B.
    J Biomol Struct Dyn; 2023 Oct 25; 41(22):13211-13227. PubMed ID: 37013977
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  • 18. Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication.
    Munke A, Persson J, Weiffert T, De Genst E, Meisl G, Arosio P, Carnerup A, Dobson CM, Vendruscolo M, Knowles TPJ, Linse S.
    Proc Natl Acad Sci U S A; 2017 Jun 20; 114(25):6444-6449. PubMed ID: 28584111
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  • 19. Protective effect of centipedegrass against Aβ oligomerization and Aβ-mediated cell death in PC12 cells.
    Song Y, Kim HD, Lee MK, Kim MK, Kang SN, Ko YG, Won CK, Kim GS, Lee SS, Bai HW, Chung BY, Cho JH.
    Pharm Biol; 2015 Jun 20; 53(9):1260-6. PubMed ID: 25853960
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