These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

313 related items for PubMed ID: 3079764

  • 1. Human liver microsomal cytochrome P-450 mephenytoin 4-hydroxylase, a prototype of genetic polymorphism in oxidative drug metabolism. Purification and characterization of two similar forms involved in the reaction.
    Shimada T, Misono KS, Guengerich FP.
    J Biol Chem; 1986 Jan 15; 261(2):909-21. PubMed ID: 3079764
    [Abstract] [Full Text] [Related]

  • 2. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
    Lasker JM, Wester MR, Aramsombatdee E, Raucy JL.
    Arch Biochem Biophys; 1998 May 01; 353(1):16-28. PubMed ID: 9578596
    [Abstract] [Full Text] [Related]

  • 3. Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase.
    Ged C, Umbenhauer DR, Bellew TM, Bork RW, Srivastava PK, Shinriki N, Lloyd RS, Guengerich FP.
    Biochemistry; 1988 Sep 06; 27(18):6929-40. PubMed ID: 3196692
    [Abstract] [Full Text] [Related]

  • 4. Separation of human liver microsomal tolbutamide hydroxylase and (S)-mephenytoin 4'-hydroxylase cytochrome P-450 enzymes.
    Srivastava PK, Yun CH, Beaune PH, Ged C, Guengerich FP.
    Mol Pharmacol; 1991 Jul 06; 40(1):69-79. PubMed ID: 1857342
    [Abstract] [Full Text] [Related]

  • 5. Genetic polymorphism of human cytochrome P-450 (S)-mephenytoin 4-hydroxylase. Studies with human autoantibodies suggest a functionally altered cytochrome P-450 isozyme as cause of the genetic deficiency.
    Meier UT, Meyer UA.
    Biochemistry; 1987 Dec 15; 26(25):8466-74. PubMed ID: 3442670
    [Abstract] [Full Text] [Related]

  • 6. Polymorphism of human cytochrome P-450.
    Guengerich FP, Umbenhauer DR, Churchill PF, Beaune PH, Böcker R, Knodell RG, Martin MV, Lloyd RS.
    Xenobiotica; 1987 Mar 15; 17(3):311-6. PubMed ID: 3577206
    [Abstract] [Full Text] [Related]

  • 7. Characterization of monkey cytochrome P450, P450 CMLd, responsible for S-mephenytoin 4-hydroxylation in hepatic microsomes of cynomolgus monkeys.
    Ohmori S, Chiba K, Nakasa H, Horie T, Kitada M.
    Arch Biochem Biophys; 1994 Jun 15; 311(2):395-401. PubMed ID: 8203903
    [Abstract] [Full Text] [Related]

  • 8. A convenient assay for mephenytoin 4-hydroxylase activity of human liver microsomal cytochrome P-450.
    Shimada T, Shea JP, Guengerich FP.
    Anal Biochem; 1985 May 15; 147(1):174-9. PubMed ID: 4025815
    [Abstract] [Full Text] [Related]

  • 9. Participation of a rat liver cytochrome P-450 induced by pregnenolone 16 alpha-carbonitrile and other compounds in the 4-hydroxylation of mephenytoin.
    Shimada T, Guengerich FP.
    Mol Pharmacol; 1985 Aug 15; 28(2):215-9. PubMed ID: 4022003
    [Abstract] [Full Text] [Related]

  • 10. Characterization and inhibition of mephenytoin 4-hydroxylase activity in human liver microsomes.
    Hall SD, Guengerich FP, Branch RA, Wilkinson GR.
    J Pharmacol Exp Ther; 1987 Jan 15; 240(1):216-22. PubMed ID: 2879902
    [Abstract] [Full Text] [Related]

  • 11. Lack of low Km diazepam N-demethylase in livers of poor metabolizers for S-mephenytoin 4'-hydroxylation.
    Yasumori T, Li QH, Yamazoe Y, Ueda M, Tsuzuki T, Kato R.
    Pharmacogenetics; 1994 Dec 15; 4(6):323-31. PubMed ID: 7704038
    [Abstract] [Full Text] [Related]

  • 12. Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
    Heyn H, White RB, Stevens JC.
    Drug Metab Dispos; 1996 Sep 15; 24(9):948-54. PubMed ID: 8886603
    [Abstract] [Full Text] [Related]

  • 13. Species differences in stereoselective metabolism of mephenytoin by cytochrome P450 (CYP2C and CYP3A).
    Yasumori T, Chen L, Nagata K, Yamazoe Y, Kato R.
    J Pharmacol Exp Ther; 1993 Jan 15; 264(1):89-94. PubMed ID: 8423554
    [Abstract] [Full Text] [Related]

  • 14. Purification and characterization of cholesterol 7 alpha-hydroxylase cytochrome P-450 of untreated rabbit liver microsomes.
    Miki N, Miura R, Miyake Y.
    J Biochem; 1987 May 15; 101(5):1087-94. PubMed ID: 3115967
    [Abstract] [Full Text] [Related]

  • 15. Cloning and sequence determination of a complementary DNA related to human liver microsomal cytochrome P-450 S-mephenytoin 4-hydroxylase.
    Umbenhauer DR, Martin MV, Lloyd RS, Guengerich FP.
    Biochemistry; 1987 Feb 24; 26(4):1094-9. PubMed ID: 3032244
    [Abstract] [Full Text] [Related]

  • 16. Formation of (R)-8-hydroxywarfarin in human liver microsomes. A new metabolic marker for the (S)-mephenytoin hydroxylase, P4502C19.
    Wienkers LC, Wurden CJ, Storch E, Kunze KL, Rettie AE, Trager WF.
    Drug Metab Dispos; 1996 May 24; 24(5):610-4. PubMed ID: 8723744
    [Abstract] [Full Text] [Related]

  • 17. The role of S-mephenytoin 4'-hydroxylase in imipramine metabolism by human liver microsomes: a two-enzyme kinetic analysis of N-demethylation and 2-hydroxylation.
    Chiba K, Saitoh A, Koyama E, Tani M, Hayashi M, Ishizaki T.
    Br J Clin Pharmacol; 1994 Mar 24; 37(3):237-42. PubMed ID: 8198931
    [Abstract] [Full Text] [Related]

  • 18. Purification and characterization of the rat liver microsomal cytochrome P-450 involved in the 4-hydroxylation of debrisoquine, a prototype for genetic variation in oxidative drug metabolism.
    Larrey D, Distlerath LM, Dannan GA, Wilkinson GR, Guengerich FP.
    Biochemistry; 1984 Jun 05; 23(12):2787-95. PubMed ID: 6432035
    [Abstract] [Full Text] [Related]

  • 19. Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes.
    Yamazaki H, Nakano M, Imai Y, Ueng YF, Guengerich FP, Shimada T.
    Arch Biochem Biophys; 1996 Jan 15; 325(2):174-82. PubMed ID: 8561495
    [Abstract] [Full Text] [Related]

  • 20. Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations.
    Inoue K, Yamazaki H, Imiya K, Akasaka S, Guengerich FP, Shimada T.
    Pharmacogenetics; 1997 Apr 15; 7(2):103-13. PubMed ID: 9170147
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 16.