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Journal Abstract Search

418 related items for PubMed ID: 30819076

  • 1. Combination of Memantine and 6-Chlorotacrine as Novel Multi-Target Compound against Alzheimer's Disease.
    Kaniakova M, Nepovimova E, Kleteckova L, Skrenkova K, Holubova K, Chrienova Z, Hepnarova V, Kucera T, Kobrlova T, Vales K, Korabecny J, Soukup O, Horak M.
    Curr Alzheimer Res; 2019; 16(9):821-833. PubMed ID: 30819076
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  • 3. Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer's disease treatment.
    Gazova Z, Soukup O, Sepsova V, Siposova K, Drtinova L, Jost P, Spilovska K, Korabecny J, Nepovimova E, Fedunova D, Horak M, Kaniakova M, Wang ZJ, Hamouda AK, Kuca K.
    Biochim Biophys Acta Mol Basis Dis; 2017 Feb; 1863(2):607-619. PubMed ID: 27865910
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  • 6. Paradigm shift in NMDA receptor antagonist drug development: molecular mechanism of uncompetitive inhibition by memantine in the treatment of Alzheimer's disease and other neurologic disorders.
    Lipton SA.
    J Alzheimers Dis; 2004 Dec; 6(6 Suppl):S61-74. PubMed ID: 15665416
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  • 7. Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease.
    Chalupova K, Korabecny J, Bartolini M, Monti B, Lamba D, Caliandro R, Pesaresi A, Brazzolotto X, Gastellier AJ, Nachon F, Pejchal J, Jarosova M, Hepnarova V, Jun D, Hrabinova M, Dolezal R, Zdarova Karasova J, Mzik M, Kristofikova Z, Misik J, Muckova L, Jost P, Soukup O, Benkova M, Setnicka V, Habartova L, Chvojkova M, Kleteckova L, Vales K, Mezeiova E, Uliassi E, Valis M, Nepovimova E, Bolognesi ML, Kuca K.
    Eur J Med Chem; 2019 Apr 15; 168():491-514. PubMed ID: 30851693
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  • 8. Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal structure and in-vitro biological evaluation.
    Manzoor S, Prajapati SK, Majumdar S, Raza MK, Gabr MT, Kumar S, Pal K, Rashid H, Kumar S, Krishnamurthy S, Hoda N.
    Eur J Med Chem; 2021 Apr 05; 215():113224. PubMed ID: 33582578
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  • 10. A molecular approach in drug development for Alzheimer's disease.
    Agatonovic-Kustrin S, Kettle C, Morton DW.
    Biomed Pharmacother; 2018 Oct 05; 106():553-565. PubMed ID: 29990843
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  • 13. Discovery of novel series of 2-substituted benzo[d]oxazol-5-amine derivatives as multi-target directed ligands for the treatment of Alzheimer's disease.
    Gutti G, Kakarla R, Kumar D, Beohar M, Ganeshpurkar A, Kumar A, Krishnamurthy S, Singh SK.
    Eur J Med Chem; 2019 Nov 15; 182():111613. PubMed ID: 31437780
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  • 14. Multifunctional tacrine-trolox hybrids for the treatment of Alzheimer's disease with cholinergic, antioxidant, neuroprotective and hepatoprotective properties.
    Xie SS, Lan JS, Wang XB, Jiang N, Dong G, Li ZR, Wang KD, Guo PP, Kong LY.
    Eur J Med Chem; 2015 Mar 26; 93():42-50. PubMed ID: 25656088
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  • 15. In vitro galantamine-memantine co-application: mechanism of beneficial action.
    Zhao X, Marszalec W, Toth PT, Huang J, Yeh JZ, Narahashi T.
    Neuropharmacology; 2006 Dec 26; 51(7-8):1181-91. PubMed ID: 17011596
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  • 16. Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-β peptide in Alzheimer's disease.
    Rosini M, Simoni E, Caporaso R, Basagni F, Catanzaro M, Abu IF, Fagiani F, Fusco F, Masuzzo S, Albani D, Lanni C, Mellor IR, Minarini A.
    Eur J Med Chem; 2019 Oct 15; 180():111-120. PubMed ID: 31301562
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  • 17. Design, synthesis and evaluation of novel 5,6,7-trimethoxyflavone-6-chlorotacrine hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Liao S, Deng H, Huang S, Yang J, Wang S, Yin B, Zheng T, Zhang D, Liu J, Gao G, Ma J, Deng Z.
    Bioorg Med Chem Lett; 2015 Apr 01; 25(7):1541-5. PubMed ID: 25724825
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  • 18. Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.
    Fernández-Bachiller MI, Pérez C, González-Muñoz GC, Conde S, López MG, Villarroya M, García AG, Rodríguez-Franco MI.
    J Med Chem; 2010 Jul 08; 53(13):4927-37. PubMed ID: 20545360
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  • 19. The molecular basis of memantine action in Alzheimer's disease and other neurologic disorders: low-affinity, uncompetitive antagonism.
    Lipton SA.
    Curr Alzheimer Res; 2005 Apr 08; 2(2):155-65. PubMed ID: 15974913
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  • 20. The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease.
    Hepnarova V, Korabecny J, Matouskova L, Jost P, Muckova L, Hrabinova M, Vykoukalova N, Kerhartova M, Kucera T, Dolezal R, Nepovimova E, Spilovska K, Mezeiova E, Pham NL, Jun D, Staud F, Kaping D, Kuca K, Soukup O.
    Eur J Med Chem; 2018 Apr 25; 150():292-306. PubMed ID: 29533874
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