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119 related items for PubMed ID: 30827841

  • 1. Structural Basis of MRG15-Mediated Activation of the ASH1L Histone Methyltransferase by Releasing an Autoinhibitory Loop.
    Lee Y, Yoon E, Cho S, Schmähling S, Müller J, Song JJ.
    Structure; 2019 May 07; 27(5):846-852.e3. PubMed ID: 30827841
    [Abstract] [Full Text] [Related]

  • 2. Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding.
    Hou P, Huang C, Liu CP, Yang N, Yu T, Yin Y, Zhu B, Xu RM.
    Structure; 2019 May 07; 27(5):837-845.e3. PubMed ID: 30827843
    [Abstract] [Full Text] [Related]

  • 3. MRG15 activates histone methyltransferase activity of ASH1L by recruiting it to the nucleosomes.
    Al-Harthi S, Li H, Winkler A, Szczepski K, Deng J, Grembecka J, Cierpicki T, Jaremko Ł.
    Structure; 2023 Oct 05; 31(10):1200-1207.e5. PubMed ID: 37527654
    [Abstract] [Full Text] [Related]

  • 4. Crystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanism.
    An S, Yeo KJ, Jeon YH, Song JJ.
    J Biol Chem; 2011 Mar 11; 286(10):8369-8374. PubMed ID: 21239497
    [Abstract] [Full Text] [Related]

  • 5. Two Loops Undergoing Concerted Dynamics Regulate the Activity of the ASH1L Histone Methyltransferase.
    Rogawski DS, Ndoj J, Cho HJ, Maillard I, Grembecka J, Cierpicki T.
    Biochemistry; 2015 Sep 08; 54(35):5401-13. PubMed ID: 26292256
    [Abstract] [Full Text] [Related]

  • 6. ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia.
    Zhu L, Li Q, Wong SH, Huang M, Klein BJ, Shen J, Ikenouye L, Onishi M, Schneidawind D, Buechele C, Hansen L, Duque-Afonso J, Zhu F, Martin GM, Gozani O, Majeti R, Kutateladze TG, Cleary ML.
    Cancer Discov; 2016 Jul 08; 6(7):770-83. PubMed ID: 27154821
    [Abstract] [Full Text] [Related]

  • 7. Regulation and function of H3K36 di-methylation by the trithorax-group protein complex AMC.
    Schmähling S, Meiler A, Lee Y, Mohammed A, Finkl K, Tauscher K, Israel L, Wirth M, Philippou-Massier J, Blum H, Habermann B, Imhof A, Song JJ, Müller J.
    Development; 2018 Apr 05; 145(7):. PubMed ID: 29540501
    [Abstract] [Full Text] [Related]

  • 8. Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity.
    Rogawski DS, Deng J, Li H, Miao H, Borkin D, Purohit T, Song J, Chase J, Li S, Ndoj J, Klossowski S, Kim E, Mao F, Zhou B, Ropa J, Krotoska MZ, Jin Z, Ernst P, Feng X, Huang G, Nishioka K, Kelly S, He M, Wen B, Sun D, Muntean A, Dou Y, Maillard I, Cierpicki T, Grembecka J.
    Nat Commun; 2021 May 14; 12(1):2792. PubMed ID: 33990599
    [Abstract] [Full Text] [Related]

  • 9. Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes.
    Gregory GD, Vakoc CR, Rozovskaia T, Zheng X, Patel S, Nakamura T, Canaani E, Blobel GA.
    Mol Cell Biol; 2007 Dec 14; 27(24):8466-79. PubMed ID: 17923682
    [Abstract] [Full Text] [Related]

  • 10. Unleashing the Power of ASH1L Methyltransferase.
    De I, Müller CW.
    Structure; 2019 May 07; 27(5):727-728. PubMed ID: 31067442
    [Abstract] [Full Text] [Related]

  • 11. Caf1 regulates the histone methyltransferase activity of Ash1 by sensing unmodified histone H3.
    Yoon E, Song JJ.
    Epigenetics Chromatin; 2023 Apr 29; 16(1):15. PubMed ID: 37118845
    [Abstract] [Full Text] [Related]

  • 12. Kinetic characterization of human histone H3 lysine 36 methyltransferases, ASH1L and SETD2.
    Eram MS, Kuznetsova E, Li F, Lima-Fernandes E, Kennedy S, Chau I, Arrowsmith CH, Schapira M, Vedadi M.
    Biochim Biophys Acta; 2015 Sep 29; 1850(9):1842-8. PubMed ID: 26002201
    [Abstract] [Full Text] [Related]

  • 13. Subunit contributions to histone methyltransferase activities of fly and worm polycomb group complexes.
    Ketel CS, Andersen EF, Vargas ML, Suh J, Strome S, Simon JA.
    Mol Cell Biol; 2005 Aug 29; 25(16):6857-68. PubMed ID: 16055700
    [Abstract] [Full Text] [Related]

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  • 16. Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins.
    Xu S, Zhong C, Zhang T, Ding J.
    J Mol Cell Biol; 2011 Oct 29; 3(5):293-300. PubMed ID: 21724641
    [Abstract] [Full Text] [Related]

  • 17. RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.
    Hayakawa T, Ohtani Y, Hayakawa N, Shinmyozu K, Saito M, Ishikawa F, Nakayama J.
    Genes Cells; 2007 Jun 29; 12(6):811-26. PubMed ID: 17573780
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  • 19. Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase.
    Sun XJ, Wei J, Wu XY, Hu M, Wang L, Wang HH, Zhang QH, Chen SJ, Huang QH, Chen Z.
    J Biol Chem; 2005 Oct 21; 280(42):35261-71. PubMed ID: 16118227
    [Abstract] [Full Text] [Related]

  • 20. Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3.
    Zhang P, Du J, Sun B, Dong X, Xu G, Zhou J, Huang Q, Liu Q, Hao Q, Ding J.
    Nucleic Acids Res; 2006 Oct 21; 34(22):6621-8. PubMed ID: 17135209
    [Abstract] [Full Text] [Related]

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