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214 related items for PubMed ID: 30841449
1. 6PGD inhibition sensitizes hepatocellular carcinoma to chemotherapy via AMPK activation and metabolic reprogramming. Chen H, Wu D, Bao L, Yin T, Lei D, Yu J, Tong X. Biomed Pharmacother; 2019 Mar; 111():1353-1358. PubMed ID: 30841449 [Abstract] [Full Text] [Related]
2. 6PGD Upregulation is Associated with Chemo- and Immuno-Resistance of Renal Cell Carcinoma via AMPK Signaling-Dependent NADPH-Mediated Metabolic Reprograming. Cao J, Sun X, Zhang X, Chen D. Am J Med Sci; 2020 Sep; 360(3):279-286. PubMed ID: 32829780 [Abstract] [Full Text] [Related]
3. Inhibiting 6-phosphogluconate dehydrogenase selectively targets breast cancer through AMPK activation. Yang X, Peng X, Huang J. Clin Transl Oncol; 2018 Sep; 20(9):1145-1152. PubMed ID: 29340974 [Abstract] [Full Text] [Related]
4. Inhibiting 6-phosphogluconate dehydrogenase enhances chemotherapy efficacy in cervical cancer via AMPK-independent inhibition of RhoA and Rac1. Guo H, Xiang Z, Zhang Y, Sun D. Clin Transl Oncol; 2019 Apr; 21(4):404-411. PubMed ID: 30182212 [Abstract] [Full Text] [Related]
5. Inhibiting 6-phosphogluconate dehydrogenase reverses doxorubicin resistance in anaplastic thyroid cancer via inhibiting NADPH-dependent metabolic reprogramming. Ma L, Cheng Q. Biochem Biophys Res Commun; 2018 Apr 15; 498(4):912-917. PubMed ID: 29534964 [Abstract] [Full Text] [Related]
6. HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress. Wang MD, Wu H, Huang S, Zhang HL, Qin CJ, Zhao LH, Fu GB, Zhou X, Wang XM, Tang L, Wen W, Yang W, Tang SH, Cao D, Guo LN, Zeng M, Wu MC, Yan HX, Wang HY. Oncotarget; 2016 Feb 09; 7(6):6711-26. PubMed ID: 26744319 [Abstract] [Full Text] [Related]
7. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Lin R, Elf S, Shan C, Kang HB, Ji Q, Zhou L, Hitosugi T, Zhang L, Zhang S, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, Mitsche M, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Hurwitz SJ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Lei Q, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J. Nat Cell Biol; 2015 Nov 09; 17(11):1484-96. PubMed ID: 26479318 [Abstract] [Full Text] [Related]
8. Regulation of SIRT1/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells. Kwon HY, Kim JH, Kim B, Srivastava SK, Kim SH. Arch Toxicol; 2018 Jan 09; 92(1):241-257. PubMed ID: 28676953 [Abstract] [Full Text] [Related]
9. 6-Phosphogluconate dehydrogenase fuels multiple aspects of cancer cells: From cancer initiation to metastasis and chemoresistance. Sarfraz I, Rasul A, Hussain G, Shah MA, Zahoor AF, Asrar M, Selamoglu Z, Ji XY, Adem Ş, Sarker SD. Biofactors; 2020 Jul 09; 46(4):550-562. PubMed ID: 32039535 [Abstract] [Full Text] [Related]
10. Simvastatin-induced cell cycle arrest through inhibition of STAT3/SKP2 axis and activation of AMPK to promote p27 and p21 accumulation in hepatocellular carcinoma cells. Wang ST, Ho HJ, Lin JT, Shieh JJ, Wu CY. Cell Death Dis; 2017 Feb 23; 8(2):e2626. PubMed ID: 28230855 [Abstract] [Full Text] [Related]
11. A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth. Gillis JL, Hinneh JA, Ryan NK, Irani S, Moldovan M, Quek LE, Shrestha RK, Hanson AR, Xie J, Hoy AJ, Holst J, Centenera MM, Mills IG, Lynn DJ, Selth LA, Butler LM. Elife; 2021 Aug 12; 10():. PubMed ID: 34382934 [Abstract] [Full Text] [Related]
12. Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin. Elf S, Lin R, Xia S, Pan Y, Shan C, Wu S, Lonial S, Gaddh M, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Boggon TJ, Fan J, Chen J. Oncogene; 2017 Jan 12; 36(2):254-262. PubMed ID: 27270429 [Abstract] [Full Text] [Related]
13. AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress. Jeon SM, Chandel NS, Hay N. Nature; 2012 May 09; 485(7400):661-5. PubMed ID: 22660331 [Abstract] [Full Text] [Related]
14. Overexpression of NAD(P)H: Quinone Oxidoreductase 1 Inhibits Hepatocellular Carcinoma Cell Proliferation and Induced Apoptosis by Activating AMPK/PGC-1α Pathway. Zhang X, Han K, Yuan DH, Meng CY. DNA Cell Biol; 2017 Apr 09; 36(4):256-263. PubMed ID: 28191864 [Abstract] [Full Text] [Related]
15. Prognostic significance of AMPK activation and therapeutic effects of metformin in hepatocellular carcinoma. Zheng L, Yang W, Wu F, Wang C, Yu L, Tang L, Qiu B, Li Y, Guo L, Wu M, Feng G, Zou D, Wang H. Clin Cancer Res; 2013 Oct 01; 19(19):5372-80. PubMed ID: 23942093 [Abstract] [Full Text] [Related]
16. Targeting AMPK, mTOR and β-Catenin by Combined Metformin and Aspirin Therapy in HCC: An Appraisal in Egyptian HCC Patients. Abdelmonsif DA, Sultan AS, El-Hadidy WF, Abdallah DM. Mol Diagn Ther; 2018 Feb 01; 22(1):115-127. PubMed ID: 29094287 [Abstract] [Full Text] [Related]
17. Inhibition of mitochondrial respiration overcomes hepatocellular carcinoma chemoresistance. Sun Y, Xu H, Chen X, Li X, Luo B. Biochem Biophys Res Commun; 2019 Jan 08; 508(2):626-632. PubMed ID: 30522865 [Abstract] [Full Text] [Related]
18. TFAM depletion overcomes hepatocellular carcinoma resistance to doxorubicin and sorafenib through AMPK activation and mitochondrial dysfunction. Zhu Y, Xu J, Hu W, Wang F, Zhou Y, Xu W, Gong W, Shao L. Gene; 2020 Aug 30; 753():144807. PubMed ID: 32461017 [Abstract] [Full Text] [Related]
19. ID1 promotes hepatocellular carcinoma proliferation and confers chemoresistance to oxaliplatin by activating pentose phosphate pathway. Yin X, Tang B, Li JH, Wang Y, Zhang L, Xie XY, Zhang BH, Qiu SJ, Wu WZ, Ren ZG. J Exp Clin Cancer Res; 2017 Nov 23; 36(1):166. PubMed ID: 29169374 [Abstract] [Full Text] [Related]
20. Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts. Zhou X, Chen J, Chen L, Feng X, Liu Z, Hu L, Zeng Z, Jia X, Liang M, Shi B, Yi G, Liu J. Cancer Lett; 2017 Dec 28; 411():1-11. PubMed ID: 28964787 [Abstract] [Full Text] [Related] Page: [Next] [New Search]