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166 related items for PubMed ID: 30843385

  • 1. Antitumor Platinium(IV) Prodrugs: A Systematic Computational Exploration of Their Reduction Mechanism by l-Ascorbic Acid.
    Dabbish E, Ponte F, Russo N, Sicilia E.
    Inorg Chem; 2019 Mar 18; 58(6):3851-3860. PubMed ID: 30843385
    [Abstract] [Full Text] [Related]

  • 2. A computational mechanistic investigation into the reduction of Pt(iv) prodrugs with two axial chlorides by biological reductants.
    Ejehi Z, Ariafard A.
    Chem Commun (Camb); 2017 Jan 24; 53(8):1413-1416. PubMed ID: 28079213
    [Abstract] [Full Text] [Related]

  • 3. Dependence of the reduction products of platinum(IV) prodrugs upon the configuration of the substrate, bulk of the carrier ligands, and nature of the reducing agent.
    Sinisi M, Intini FP, Natile G.
    Inorg Chem; 2012 Sep 17; 51(18):9694-704. PubMed ID: 22921246
    [Abstract] [Full Text] [Related]

  • 4. Reduction of ormaplatin and cis-diamminetetrachloroplatinum(iv) by ascorbic acid and dominant thiols in human plasma: kinetic and mechanistic analyses.
    Dong J, Ren Y, Huo S, Shen S, Xu J, Tian H, Shi T.
    Dalton Trans; 2016 Jul 28; 45(28):11326-37. PubMed ID: 27327648
    [Abstract] [Full Text] [Related]

  • 5. Insights from Computations on the Mechanism of Reduction by Ascorbic Acid of PtIV Prodrugs with Asplatin and Its Chlorido and Bromido Analogues as Model Systems.
    Ponte F, Russo N, Sicilia E.
    Chemistry; 2018 Jul 05; 24(38):9572-9580. PubMed ID: 29723436
    [Abstract] [Full Text] [Related]

  • 6. Pt(IV) analogs of oxaliplatin that do not follow the expected correlation between electrochemical reduction potential and rate of reduction by ascorbate.
    Zhang JZ, Wexselblatt E, Hambley TW, Gibson D.
    Chem Commun (Camb); 2012 Jan 21; 48(6):847-9. PubMed ID: 22124352
    [Abstract] [Full Text] [Related]

  • 7. Multi-Acting Mitochondria-Targeted Platinum(IV) Prodrugs of Kiteplatin with α-Lipoic Acid in the Axial Positions.
    Savino S, Marzano C, Gandin V, Hoeschele JD, Natile G, Margiotta N.
    Int J Mol Sci; 2018 Jul 14; 19(7):. PubMed ID: 30011897
    [Abstract] [Full Text] [Related]

  • 8. Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs.
    Ravera M, Gabano E, Zanellato I, Bonarrigo I, Alessio M, Arnesano F, Galliani A, Natile G, Osella D.
    J Inorg Biochem; 2015 Sep 14; 150():1-8. PubMed ID: 26042542
    [Abstract] [Full Text] [Related]

  • 9. Platinum(IV) Complexes of trans-1,2-diamino-4-cyclohexene: Prodrugs Affording an Oxaliplatin Analogue that Overcomes Cancer Resistance.
    Papadia P, Micoli K, Barbanente A, Ditaranto N, Hoeschele JD, Natile G, Marzano C, Gandin V, Margiotta N.
    Int J Mol Sci; 2020 Mar 27; 21(7):. PubMed ID: 32230896
    [Abstract] [Full Text] [Related]

  • 10. Iodido equatorial ligands influence on the mechanism of action of Pt(IV) and Pt(II) anti-cancer complexes: A DFT computational study.
    Scoditti S, Vigna V, Dabbish E, Sicilia E.
    J Comput Chem; 2021 Apr 05; 42(9):608-619. PubMed ID: 33469953
    [Abstract] [Full Text] [Related]

  • 11. Importance of platinum(II)-assisted platinum(IV) substitution for the oxidation of guanosine derivatives by platinum(IV) complexes.
    Choi S, Vastag L, Larrabee YC, Personick ML, Schaberg KB, Fowler BJ, Sandwick RK, Rawji G.
    Inorg Chem; 2008 Feb 18; 47(4):1352-60. PubMed ID: 18220340
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, Structure, and Cytotoxicity of Oxaliplatin-Based Platinum(IV) Anticancer Prodrugs Bearing One Axial Fluoride.
    Xu Z, Chan HM, Li C, Wang Z, Tse MK, Tong Z, Zhu G.
    Inorg Chem; 2018 Jul 16; 57(14):8227-8235. PubMed ID: 29943979
    [Abstract] [Full Text] [Related]

  • 13. Investigation of the Inertness to Hydrolysis of Platinum(IV) Prodrugs.
    Ritacco I, Mazzone G, Russo N, Sicilia E.
    Inorg Chem; 2016 Feb 15; 55(4):1580-6. PubMed ID: 26812023
    [Abstract] [Full Text] [Related]

  • 14. A multi-methodological inquiry of the behavior of cisplatin-based Pt(IV) derivatives in the presence of bioreductants with a focus on the isolated encounter complexes.
    Corinti D, Crestoni ME, Fornarini S, Dabbish E, Sicilia E, Gabano E, Perin E, Osella D.
    J Biol Inorg Chem; 2020 Jun 15; 25(4):655-670. PubMed ID: 32296997
    [Abstract] [Full Text] [Related]

  • 15. Influence of equatorial and axial carboxylato ligands on the kinetic inertness of platinum(IV) complexes in the presence of ascorbate and cysteine and within DLD-1 cancer cells.
    Chen CK, Zhang JZ, Aitken JB, Hambley TW.
    J Med Chem; 2013 Nov 14; 56(21):8757-64. PubMed ID: 24107138
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  • 20. Kinetics and mechanism for reduction of the anticancer prodrug trans,trans,trans-[PtCl2(OH)2(c-C6H11NH2)(NH3)] (JM335) by thiols.
    Lemma K, Shi T, Elding LI.
    Inorg Chem; 2000 Apr 17; 39(8):1728-34. PubMed ID: 12526561
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