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385 related items for PubMed ID: 30849662

  • 1. Ex vivo resistance in childhood acute lymphoblastic leukemia: Correlations between BCRP, MRP1, MRP4 and MRP5 ABC transporter expression and intracellular methotrexate polyglutamate accumulation.
    Jaramillo AC, Cloos J, Lemos C, Stam RW, Kaspers GJL, Jansen G, Peters GJ.
    Leuk Res; 2019 Apr; 79():45-51. PubMed ID: 30849662
    [Abstract] [Full Text] [Related]

  • 2. Lack of an effect of breast cancer resistance protein (BCRP/ABCG2) overexpression on methotrexate polyglutamate export and folate accumulation in a human breast cancer cell line.
    Rhee MS, Schneider E.
    Biochem Pharmacol; 2005 Jan 01; 69(1):123-32. PubMed ID: 15588721
    [Abstract] [Full Text] [Related]

  • 3. Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.
    Rots MG, Pieters R, Kaspers GJ, van Zantwijk CH, Noordhuis P, Mauritz R, Veerman AJ, Jansen G, Peters GJ.
    Blood; 1999 Feb 01; 93(3):1067-74. PubMed ID: 9920857
    [Abstract] [Full Text] [Related]

  • 4. Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter.
    Volk EL, Schneider E.
    Cancer Res; 2003 Sep 01; 63(17):5538-43. PubMed ID: 14500392
    [Abstract] [Full Text] [Related]

  • 5. Multidrug resistance genes in infant acute lymphoblastic leukemia: Ara-C is not a substrate for the breast cancer resistance protein.
    Stam RW, van den Heuvel-Eibrink MM, den Boer ML, Ebus ME, Janka-Schaub GE, Allen JD, Pieters R.
    Leukemia; 2004 Jan 01; 18(1):78-83. PubMed ID: 14574327
    [Abstract] [Full Text] [Related]

  • 6. Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia.
    Wojtuszkiewicz A, Peters GJ, van Woerden NL, Dubbelman B, Escherich G, Schmiegelow K, Sonneveld E, Pieters R, van de Ven PM, Jansen G, Assaraf YG, Kaspers GJ, Cloos J.
    J Hematol Oncol; 2015 May 29; 8():61. PubMed ID: 26022503
    [Abstract] [Full Text] [Related]

  • 7. Folate deprivation results in the loss of breast cancer resistance protein (BCRP/ABCG2) expression. A role for BCRP in cellular folate homeostasis.
    Ifergan I, Shafran A, Jansen G, Hooijberg JH, Scheffer GL, Assaraf YG.
    J Biol Chem; 2004 Jun 11; 279(24):25527-34. PubMed ID: 15047700
    [Abstract] [Full Text] [Related]

  • 8. Expression of multidrug resistance 1 (MDR1), multidrug resistance-related protein 1 (MRP1), lung resistance protein (LRP), and breast cancer resistance protein (BCRP) genes and clinical outcome in childhood acute lymphoblastic leukemia.
    Kourti M, Vavatsi N, Gombakis N, Sidi V, Tzimagiorgis G, Papageorgiou T, Koliouskas D, Athanassiadou F.
    Int J Hematol; 2007 Aug 11; 86(2):166-73. PubMed ID: 17875533
    [Abstract] [Full Text] [Related]

  • 9. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia.
    Synold TW, Relling MV, Boyett JM, Rivera GK, Sandlund JT, Mahmoud H, Crist WM, Pui CH, Evans WE.
    J Clin Invest; 1994 Nov 11; 94(5):1996-2001. PubMed ID: 7525652
    [Abstract] [Full Text] [Related]

  • 10. Reduced folate carrier expression in acute lymphoblastic leukemia: a mechanism for ploidy but not lineage differences in methotrexate accumulation.
    Belkov VM, Krynetski EY, Schuetz JD, Yanishevski Y, Masson E, Mathew S, Raimondi S, Pui CH, Relling MV, Evans WE.
    Blood; 1999 Mar 01; 93(5):1643-50. PubMed ID: 10029593
    [Abstract] [Full Text] [Related]

  • 11. ABCB1 and ABCG2 proteins, their functional activity and gene expression in concert with drug sensitivity of leukemia cells.
    Svirnovski AI, Shman TV, Serhiyenka TF, Savitski VP, Smolnikova VV, Fedasenka UU.
    Hematology; 2009 Aug 01; 14(4):204-12. PubMed ID: 19635183
    [Abstract] [Full Text] [Related]

  • 12. Hyperuricemia influences tryptophan metabolism via inhibition of multidrug resistance protein 4 (MRP4) and breast cancer resistance protein (BCRP).
    Dankers AC, Mutsaers HA, Dijkman HB, van den Heuvel LP, Hoenderop JG, Sweep FC, Russel FG, Masereeuw R.
    Biochim Biophys Acta; 2013 Oct 01; 1832(10):1715-22. PubMed ID: 23665398
    [Abstract] [Full Text] [Related]

  • 13. Characterization of SN38-resistant T47D breast cancer cell sublines overexpressing BCRP, MRP1, MRP2, MRP3, and MRP4.
    Lee HJ, Choi CH.
    BMC Cancer; 2022 Apr 23; 22(1):446. PubMed ID: 35461219
    [Abstract] [Full Text] [Related]

  • 14. Basis for natural resistance to methotrexate in human acute non-lymphocytic leukemia.
    Lin JT, Tong WP, Trippett TM, Niedzwiecki D, Tao Y, Tan C, Steinherz P, Schweitzer BI, Bertino JR.
    Leuk Res; 1991 Apr 23; 15(12):1191-6. PubMed ID: 1722550
    [Abstract] [Full Text] [Related]

  • 15. Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system.
    Chen ZS, Lee K, Walther S, Raftogianis RB, Kuwano M, Zeng H, Kruh GD.
    Cancer Res; 2002 Jun 01; 62(11):3144-50. PubMed ID: 12036927
    [Abstract] [Full Text] [Related]

  • 16. Cellular folate status modulates the expression of BCRP and MRP multidrug transporters in cancer cell lines from different origins.
    Lemos C, Kathmann I, Giovannetti E, Beliën JA, Scheffer GL, Calhau C, Jansen G, Peters GJ.
    Mol Cancer Ther; 2009 Mar 01; 8(3):655-64. PubMed ID: 19240161
    [Abstract] [Full Text] [Related]

  • 17. Inflammatory regulation of ATP binding cassette efflux transporter expression and function in microglia.
    Gibson CJ, Hossain MM, Richardson JR, Aleksunes LM.
    J Pharmacol Exp Ther; 2012 Dec 01; 343(3):650-60. PubMed ID: 22942241
    [Abstract] [Full Text] [Related]

  • 18. [Study on the relationship between the resistance to MTX and the transport protein superfamily of ATP-binding cassette that induces multiple drug resistance].
    Zhang CY, Feng YX, Li P, Fu SB.
    Yi Chuan; 2006 Oct 01; 28(10):1201-5. PubMed ID: 17035174
    [Abstract] [Full Text] [Related]

  • 19. Ganciclovir and Its Hemocompatible More Lipophilic Derivative Can Enhance the Apoptotic Effects of Methotrexate by Inhibiting Breast Cancer Resistance Protein (BCRP).
    Markowicz-Piasecka M, Huttunen J, Montaser A, Adla SK, Auriola S, Lehtonen M, Huttunen KM.
    Int J Mol Sci; 2021 Jul 20; 22(14):. PubMed ID: 34299347
    [Abstract] [Full Text] [Related]

  • 20. Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy.
    Leclerc GJ, Mou C, Leclerc GM, Mian AM, Barredo JC.
    Leukemia; 2010 Mar 20; 24(3):552-62. PubMed ID: 20072153
    [Abstract] [Full Text] [Related]

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