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Journal Abstract Search

389 related items for PubMed ID: 30858281

  • 1.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 2. Reconstitution of sterol-regulated endoplasmic reticulum-to-Golgi transport of SREBP-2 in insect cells by co-expression of mammalian SCAP and Insigs.
    Dobrosotskaya IY, Goldstein JL, Brown MS, Rawson RB.
    J Biol Chem; 2003 Sep 12; 278(37):35837-43. PubMed ID: 12842885
    [Abstract] [Full Text] [Related]

  • 3. Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins.
    Sun LP, Seemann J, Goldstein JL, Brown MS.
    Proc Natl Acad Sci U S A; 2007 Apr 17; 104(16):6519-26. PubMed ID: 17428919
    [Abstract] [Full Text] [Related]

  • 4. PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus.
    Xu D, Wang Z, Zhang Y, Jiang W, Pan Y, Song BL, Chen Y.
    Nat Commun; 2015 Aug 27; 6():8100. PubMed ID: 26311497
    [Abstract] [Full Text] [Related]

  • 5. Insulin enhances the biogenesis of nuclear sterol regulatory element-binding protein (SREBP)-1c by posttranscriptional down-regulation of Insig-2A and its dissociation from SREBP cleavage-activating protein (SCAP).SREBP-1c complex.
    Yellaturu CR, Deng X, Park EA, Raghow R, Elam MB.
    J Biol Chem; 2009 Nov 13; 284(46):31726-34. PubMed ID: 19759400
    [Abstract] [Full Text] [Related]

  • 6. COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions.
    Takashima K, Saitoh A, Funabashi T, Hirose S, Yagi C, Nozaki S, Sato R, Shin HW, Nakayama K.
    J Cell Sci; 2015 Aug 01; 128(15):2805-15. PubMed ID: 26092941
    [Abstract] [Full Text] [Related]

  • 7. Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro.
    Sun LP, Li L, Goldstein JL, Brown MS.
    J Biol Chem; 2005 Jul 15; 280(28):26483-90. PubMed ID: 15899885
    [Abstract] [Full Text] [Related]

  • 8. Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.
    Yang T, Espenshade PJ, Wright ME, Yabe D, Gong Y, Aebersold R, Goldstein JL, Brown MS.
    Cell; 2002 Aug 23; 110(4):489-500. PubMed ID: 12202038
    [Abstract] [Full Text] [Related]

  • 9. Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles.
    Yellaturu CR, Deng X, Cagen LM, Wilcox HG, Mansbach CM, Siddiqi SA, Park EA, Raghow R, Elam MB.
    J Biol Chem; 2009 Mar 20; 284(12):7518-32. PubMed ID: 19158095
    [Abstract] [Full Text] [Related]

  • 10. Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner.
    Shao W, Machamer CE, Espenshade PJ.
    J Lipid Res; 2016 Aug 20; 57(8):1564-73. PubMed ID: 27324795
    [Abstract] [Full Text] [Related]

  • 11.
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    [No Abstract] [Full Text] [Related]

  • 12. Sterols block binding of COPII proteins to SCAP, thereby controlling SCAP sorting in ER.
    Espenshade PJ, Li WP, Yabe D.
    Proc Natl Acad Sci U S A; 2002 Sep 03; 99(18):11694-9. PubMed ID: 12193656
    [Abstract] [Full Text] [Related]

  • 13. Assaying Sterol-Regulated ER-to-Golgi Transport of SREBP Cleavage-Activating Protein Using Immunofluorescence Microscopy.
    Ishida CT, Shao W, Espenshade PJ.
    Methods Mol Biol; 2023 Sep 03; 2557():755-764. PubMed ID: 36512249
    [Abstract] [Full Text] [Related]

  • 14. Point mutation in luminal loop 7 of Scap protein blocks interaction with loop 1 and abolishes movement to Golgi.
    Zhang Y, Motamed M, Seemann J, Brown MS, Goldstein JL.
    J Biol Chem; 2013 May 17; 288(20):14059-14067. PubMed ID: 23564452
    [Abstract] [Full Text] [Related]

  • 15. Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth.
    Cheng C, Ru P, Geng F, Liu J, Yoo JY, Wu X, Cheng X, Euthine V, Hu P, Guo JY, Lefai E, Kaur B, Nohturfft A, Ma J, Chakravarti A, Guo D.
    Cancer Cell; 2015 Nov 09; 28(5):569-581. PubMed ID: 26555173
    [Abstract] [Full Text] [Related]

  • 16. Overexpression of membrane domain of SCAP prevents sterols from inhibiting SCAP.SREBP exit from endoplasmic reticulum.
    Yang T, Goldstein JL, Brown MS.
    J Biol Chem; 2000 Sep 22; 275(38):29881-6. PubMed ID: 10896675
    [Abstract] [Full Text] [Related]

  • 17. A novel processing system of sterol regulatory element-binding protein-1c regulated by polyunsaturated fatty acid.
    Nakakuki M, Kawano H, Notsu T, Imada K, Mizuguchi K, Shimano H.
    J Biochem; 2014 May 22; 155(5):301-13. PubMed ID: 24729033
    [Abstract] [Full Text] [Related]

  • 18. The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces SREBP-2 cleavage.
    Irisawa M, Inoue J, Ozawa N, Mori K, Sato R.
    J Biol Chem; 2009 Oct 16; 284(42):28995-9004. PubMed ID: 19706601
    [Abstract] [Full Text] [Related]

  • 19. Identification of luminal Loop 1 of Scap protein as the sterol sensor that maintains cholesterol homeostasis.
    Motamed M, Zhang Y, Wang ML, Seemann J, Kwon HJ, Goldstein JL, Brown MS.
    J Biol Chem; 2011 May 20; 286(20):18002-12. PubMed ID: 21454655
    [Abstract] [Full Text] [Related]

  • 20. Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake.
    Gong Y, Lee JN, Lee PC, Goldstein JL, Brown MS, Ye J.
    Cell Metab; 2006 Jan 20; 3(1):15-24. PubMed ID: 16399501
    [Abstract] [Full Text] [Related]

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