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Journal Abstract Search

175 related items for PubMed ID: 30863203

  • 1. TNF-α Downregulation Modifies Insulin Receptor Substrate 1 (IRS-1) in Metabolic Signaling of Diabetic Insulin-Resistant Hepatocytes.
    Alipourfard I, Datukishvili N, Mikeladze D.
    Mediators Inflamm; 2019; 2019():3560819. PubMed ID: 30863203
    [Abstract] [Full Text] [Related]

  • 2. The Key Role of Akt Protein Kinase in Metabolic-Inflammatory Pathways Cross-Talk: TNF-α Down-Regulation and Improving of Insulin Resistance in HepG2 Cell Line.
    Alipourfard I, Bakhtiyari S, Gheysarzadeh A, Di Renzo L, De Lorenzo A, Mikeladze D, Khamoushi A.
    Curr Mol Med; 2021; 21(3):257-264. PubMed ID: 32338219
    [Abstract] [Full Text] [Related]

  • 3. Modified Si-Miao-San extract inhibits inflammatory response and modulates insulin sensitivity in hepatocytes through an IKKβ/IRS-1/Akt-dependent pathway.
    Liu K, Luo T, Zhang Z, Wang T, Kou J, Liu B, Huang F.
    J Ethnopharmacol; 2011 Jul 14; 136(3):473-9. PubMed ID: 21296137
    [Abstract] [Full Text] [Related]

  • 4. S6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2.
    Zhang J, Gao Z, Yin J, Quon MJ, Ye J.
    J Biol Chem; 2008 Dec 19; 283(51):35375-82. PubMed ID: 18952604
    [Abstract] [Full Text] [Related]

  • 5. MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells.
    Yang WM, Min KH, Lee W.
    Biochem Biophys Res Commun; 2016 Sep 30; 478(4):1786-91. PubMed ID: 27613089
    [Abstract] [Full Text] [Related]

  • 6. Palmitate affects insulin receptor phosphorylation and intracellular insulin signal in a pancreatic alpha-cell line.
    Piro S, Maniscalchi ET, Monello A, Pandini G, Mascali LG, Rabuazzo AM, Purrello F.
    Endocrinology; 2010 Sep 30; 151(9):4197-206. PubMed ID: 20573722
    [Abstract] [Full Text] [Related]

  • 7. TNF-α knockdown alleviates palmitate-induced insulin resistance in C2C12 skeletal muscle cells.
    Haghani K, Pashaei S, Vakili S, Taheripak G, Bakhtiyari S.
    Biochem Biophys Res Commun; 2015 May 15; 460(4):977-82. PubMed ID: 25839650
    [Abstract] [Full Text] [Related]

  • 8. Protein phosphatase 4 (PP4) functions as a critical regulator in tumor necrosis factor (TNF)-α-induced hepatic insulin resistance.
    Zhao H, Huang X, Jiao J, Zhang H, Liu J, Qin W, Meng X, Shen T, Lin Y, Chu J, Li J.
    Sci Rep; 2015 Dec 15; 5():18093. PubMed ID: 26666849
    [Abstract] [Full Text] [Related]

  • 9. Timosaponin B-II Ameliorates Palmitate-Induced Insulin Resistance and Inflammation via IRS-1/PI3K/Akt and IKK/NF-[Formula: see text]B Pathways.
    Yuan YL, Lin BQ, Zhang CF, Cui LL, Ruan SX, Yang ZL, Li F, Ji D.
    Am J Chin Med; 2016 Dec 15; 44(4):755-69. PubMed ID: 27222060
    [Abstract] [Full Text] [Related]

  • 10. MiR-183-5p Induced by Saturated Fatty Acids Hinders Insulin Signaling by Downregulating IRS-1 in Hepatocytes.
    Nguyen MT, Min KH, Lee W.
    Int J Mol Sci; 2022 Mar 10; 23(6):. PubMed ID: 35328400
    [Abstract] [Full Text] [Related]

  • 11. 4-Hydroxyisoleucine improves insulin resistance in HepG2 cells by decreasing TNF-α and regulating the expression of insulin signal transduction proteins.
    Gao F, Jian L, Zafar MI, Du W, Cai Q, Shafqat RA, Lu F.
    Mol Med Rep; 2015 Nov 10; 12(5):6555-60. PubMed ID: 26352439
    [Abstract] [Full Text] [Related]

  • 12. Cross-talk mechanisms in the development of insulin resistance of skeletal muscle cells palmitate rather than tumour necrosis factor inhibits insulin-dependent protein kinase B (PKB)/Akt stimulation and glucose uptake.
    Storz P, Döppler H, Wernig A, Pfizenmaier K, Müller G.
    Eur J Biochem; 1999 Nov 10; 266(1):17-25. PubMed ID: 10542046
    [Abstract] [Full Text] [Related]

  • 13. Serine 307 on insulin receptor substrate 1 is required for SOCS3 and TNF-α signaling in the rMC-1 cell line.
    Jiang Y, Biswas SK, Steinle JJ.
    Mol Vis; 2014 Nov 10; 20():1463-70. PubMed ID: 25352752
    [Abstract] [Full Text] [Related]

  • 14. Induction of miR-96 by Dietary Saturated Fatty Acids Exacerbates Hepatic Insulin Resistance through the Suppression of INSR and IRS-1.
    Yang WM, Min KH, Lee W.
    PLoS One; 2016 Nov 10; 11(12):e0169039. PubMed ID: 28036389
    [Abstract] [Full Text] [Related]

  • 15. Arg972 insulin receptor substrate-1 enhances tumor necrosis factor-α-induced apoptosis in osteoblasts.
    You Y, Liu S, Peng L, Long M, Deng H, Zhao H.
    Mol Med Rep; 2015 Jul 10; 12(1):255-60. PubMed ID: 25760103
    [Abstract] [Full Text] [Related]

  • 16. Diosgenin ameliorates palmitate-induced endothelial dysfunction and insulin resistance via blocking IKKβ and IRS-1 pathways.
    Liu K, Zhao W, Gao X, Huang F, Kou J, Liu B.
    Atherosclerosis; 2012 Aug 10; 223(2):350-8. PubMed ID: 22766331
    [Abstract] [Full Text] [Related]

  • 17. Visfatin Induces Inflammation and Insulin Resistance via the NF-κB and STAT3 Signaling Pathways in Hepatocytes.
    Heo YJ, Choi SE, Jeon JY, Han SJ, Kim DJ, Kang Y, Lee KW, Kim HJ.
    J Diabetes Res; 2019 Aug 10; 2019():4021623. PubMed ID: 31396538
    [Abstract] [Full Text] [Related]

  • 18. Paradoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo.
    Yang P, Zhao Y, Zhao L, Yuan J, Chen Y, Varghese Z, Moorhead JF, Chen Y, Ruan XZ.
    Sci Rep; 2015 Oct 09; 5():14959. PubMed ID: 26449763
    [Abstract] [Full Text] [Related]

  • 19. Paeoniflorin suppresses lipid accumulation and alleviates insulin resistance by regulating the Rho kinase/IRS-1 pathway in palmitate-induced HepG2Cells.
    Ma Z, Liu H, Wang W, Guan S, Yi J, Chu L.
    Biomed Pharmacother; 2017 Jun 09; 90():361-367. PubMed ID: 28380411
    [Abstract] [Full Text] [Related]

  • 20. Berberine inhibits inflammatory response and ameliorates insulin resistance in hepatocytes.
    Lou T, Zhang Z, Xi Z, Liu K, Li L, Liu B, Huang F.
    Inflammation; 2011 Dec 09; 34(6):659-67. PubMed ID: 21110076
    [Abstract] [Full Text] [Related]

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