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259 related items for PubMed ID: 30934922

  • 1. Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines.
    Prabhu KS, Siveen KS, Kuttikrishnan S, Jochebeth A, Ali TA, Elareer NR, Iskandarani A, Quaiyoom Khan A, Merhi M, Dermime S, El-Elimat T, Oberlies NH, Alali FQ, Steinhoff M, Uddin S.
    Biomolecules; 2019 Mar 29; 9(4):. PubMed ID: 30934922
    [Abstract] [Full Text] [Related]

  • 2. Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines.
    Prabhu KS, Siveen KS, Kuttikrishnan S, Iskandarani AN, Khan AQ, Merhi M, Omri HE, Dermime S, El-Elimat T, Oberlies NH, Alali FQ, Uddin S.
    Front Pharmacol; 2018 Mar 29; 9():720. PubMed ID: 30061828
    [Abstract] [Full Text] [Related]

  • 3. Sanguinarine suppresses growth and induces apoptosis in childhood acute lymphoblastic leukemia.
    Kuttikrishnan S, Siveen KS, Prabhu KS, Khan AQ, Akhtar S, Mateo JM, Merhi M, Taha R, Omri HE, Mraiche F, Dermime S, Uddin S.
    Leuk Lymphoma; 2019 Mar 29; 60(3):782-794. PubMed ID: 30187808
    [Abstract] [Full Text] [Related]

  • 4. Induction of apoptosis in MDA-MB-231 human breast carcinoma cells with an ethanol extract of Cyperus rotundus L. by activating caspases.
    Park SE, Shin WT, Park C, Hong SH, Kim GY, Kim SO, Ryu CH, Hong SH, Choi YH.
    Oncol Rep; 2014 Dec 29; 32(6):2461-70. PubMed ID: 25241797
    [Abstract] [Full Text] [Related]

  • 5. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Dec 29; 9():1555-84. PubMed ID: 25792811
    [Abstract] [Full Text] [Related]

  • 6. N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells.
    Kim BM, Choi YJ, Han Y, Yun YS, Hong SH.
    Toxicol Appl Pharmacol; 2009 Aug 15; 239(1):87-97. PubMed ID: 19481559
    [Abstract] [Full Text] [Related]

  • 7. Investigation of the mechanism and apoptotic pathway induced by 4β cinnamido linked podophyllotoxins against human lung cancer cells A549.
    Kamal A, Nayak VL, Bagul C, Vishnuvardhan MV, Mallareddy A.
    Apoptosis; 2015 Nov 15; 20(11):1518-29. PubMed ID: 26386574
    [Abstract] [Full Text] [Related]

  • 8. Deltonin isolated from Dioscorea zingiberensis inhibits cancer cell growth through inducing mitochondrial apoptosis and suppressing Akt and mitogen activated protein kinase signals.
    Shu D, Qing Y, Tong Q, He Y, Xing Z, Zhao Y, Li Y, Wei Y, Huang W, Wu X.
    Biol Pharm Bull; 2011 Nov 15; 34(8):1231-9. PubMed ID: 21804211
    [Abstract] [Full Text] [Related]

  • 9. Targeting of X-linked inhibitor of apoptosis protein and PI3-kinase/AKT signaling by embelin suppresses growth of leukemic cells.
    Prabhu KS, Siveen KS, Kuttikrishnan S, Iskandarani A, Tsakou M, Achkar IW, Therachiyil L, Krishnankutty R, Parray A, Kulinski M, Merhi M, Dermime S, Mohammad RM, Uddin S.
    PLoS One; 2017 Nov 15; 12(7):e0180895. PubMed ID: 28704451
    [Abstract] [Full Text] [Related]

  • 10. Polyphenols from Korean prostrate spurge Euphorbia supina induce apoptosis through the Fas-associated extrinsic pathway and activation of ERK in human leukemic U937 cells.
    Han MH, Lee WS, Nagappan A, Kim HJ, Park C, Kim GY, Hong SH, Kim ND, Kim G, Ryu CH, Shin SC, Choi YH.
    Oncol Rep; 2016 Jul 15; 36(1):99-107. PubMed ID: 27122127
    [Abstract] [Full Text] [Related]

  • 11. Plumbagin engenders apoptosis in lung cancer cells via caspase-9 activation and targeting mitochondrial-mediated ROS induction.
    Tripathi SK, Rengasamy KRR, Biswal BK.
    Arch Pharm Res; 2020 Feb 15; 43(2):242-256. PubMed ID: 32034669
    [Abstract] [Full Text] [Related]

  • 12. ω-hydroxyundec-9-enoic acid induction of breast cancer cells apoptosis through generation of mitochondrial ROS and phosphorylation of AMPK.
    Ahn J, Kim H, Yang KM.
    Arch Pharm Res; 2020 Jul 15; 43(7):735-743. PubMed ID: 32720162
    [Abstract] [Full Text] [Related]

  • 13. Diallyl trisulfide-induced apoptosis of bladder cancer cells is caspase-dependent and regulated by PI3K/Akt and JNK pathways.
    Shin DY, Kim GY, Hwang HJ, Kim WJ, Choi YH.
    Environ Toxicol Pharmacol; 2014 Jan 15; 37(1):74-83. PubMed ID: 24309133
    [Abstract] [Full Text] [Related]

  • 14. BL-038, a Benzofuran Derivative, Induces Cell Apoptosis in Human Chondrosarcoma Cells through Reactive Oxygen Species/Mitochondrial Dysfunction and the Caspases Dependent Pathway.
    Liu JF, Chen CY, Chen HT, Chang CS, Tang CH.
    Int J Mol Sci; 2016 Sep 07; 17(9):. PubMed ID: 27618007
    [Abstract] [Full Text] [Related]

  • 15. Involvement of mitochondria and caspase-3 in ET-18-OCH(3)-induced apoptosis of human leukemic cells.
    Gajate C, Santos-Beneit AM, Macho A, Lazaro Md, Hernandez-De Rojas A, Modolell M, Muñoz E, Mollinedo F.
    Int J Cancer; 2000 Apr 15; 86(2):208-18. PubMed ID: 10738248
    [Abstract] [Full Text] [Related]

  • 16. Furazolidone induces apoptosis through activating reactive oxygen species-dependent mitochondrial signaling pathway and suppressing PI3K/Akt signaling pathway in HepG2 cells.
    Deng S, Tang S, Zhang S, Zhang C, Wang C, Zhou Y, Dai C, Xiao X.
    Food Chem Toxicol; 2015 Jan 15; 75():173-86. PubMed ID: 25434308
    [Abstract] [Full Text] [Related]

  • 17. Curcumin induces apoptosis in human neuroblastoma cells via inhibition of AKT and Foxo3a nuclear translocation.
    Picone P, Nuzzo D, Caruana L, Messina E, Scafidi V, Di Carlo M.
    Free Radic Res; 2014 Dec 15; 48(12):1397-408. PubMed ID: 25179440
    [Abstract] [Full Text] [Related]

  • 18. Apoptosis induction of human prostate carcinoma cells by cordycepin through reactive oxygen species‑mediated mitochondrial death pathway.
    Lee HH, Park C, Jeong JW, Kim MJ, Seo MJ, Kang BW, Park JU, Kim GY, Choi BT, Choi YH, Jeong YK.
    Int J Oncol; 2013 Mar 15; 42(3):1036-44. PubMed ID: 23292300
    [Abstract] [Full Text] [Related]

  • 19. Increased apoptotic efficacy of lonidamine plus arsenic trioxide combination in human leukemia cells. Reactive oxygen species generation and defensive protein kinase (MEK/ERK, Akt/mTOR) modulation.
    Calviño E, Estañ MC, Simón GP, Sancho P, Boyano-Adánez Mdel C, de Blas E, Bréard J, Aller P.
    Biochem Pharmacol; 2011 Dec 01; 82(11):1619-29. PubMed ID: 21889928
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, biological evaluation and mechanism studies of C-23 modified 23-hydroxybetulinic acid derivatives as anticancer agents.
    Lu L, Zhang H, Liu J, Liu Y, Wang Y, Xu S, Zhu Z, Xu J.
    Eur J Med Chem; 2019 Nov 15; 182():111659. PubMed ID: 31491611
    [Abstract] [Full Text] [Related]

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