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Journal Abstract Search

241 related items for PubMed ID: 30934952

  • 1. Structural Stabilization of Human Transthyretin by Centella asiatica (L.) Urban Extract: Implications for TTR Amyloidosis.
    Eze FN, Leelawatwattana L, Prapunpoj P.
    Biomolecules; 2019 Mar 29; 9(4):. PubMed ID: 30934952
    [Abstract] [Full Text] [Related]

  • 2. Transthyretin Anti-Amyloidogenic and Fibril Disrupting Activities of Bacopa monnieri (L.) Wettst (Brahmi) Extract.
    Eze FN, Ingkaninan K, Prapunpoj P.
    Biomolecules; 2019 Dec 09; 9(12):. PubMed ID: 31835306
    [Abstract] [Full Text] [Related]

  • 3. Kinetic stabilization of an oligomeric protein under physiological conditions demonstrated by a lack of subunit exchange: implications for transthyretin amyloidosis.
    Wiseman RL, Green NS, Kelly JW.
    Biochemistry; 2005 Jun 28; 44(25):9265-74. PubMed ID: 15966751
    [Abstract] [Full Text] [Related]

  • 4. Kinetic stabilization of the native state by protein engineering: implications for inhibition of transthyretin amyloidogenesis.
    Foss TR, Kelker MS, Wiseman RL, Wilson IA, Kelly JW.
    J Mol Biol; 2005 Apr 08; 347(4):841-54. PubMed ID: 15769474
    [Abstract] [Full Text] [Related]

  • 5. Specific disruption of transthyretin(105-115) fibrilization using "stabilizing" inhibitors of transthyretin amyloidogenesis.
    Liang Y, Ore MO, Morin S, Wilson DJ.
    Biochemistry; 2012 Apr 24; 51(16):3523-30. PubMed ID: 22482799
    [Abstract] [Full Text] [Related]

  • 6. Genistein, a natural product from soy, is a potent inhibitor of transthyretin amyloidosis.
    Green NS, Foss TR, Kelly JW.
    Proc Natl Acad Sci U S A; 2005 Oct 11; 102(41):14545-50. PubMed ID: 16195386
    [Abstract] [Full Text] [Related]

  • 7. Quantification of the thermodynamically linked quaternary and tertiary structural stabilities of transthyretin and its disease-associated variants: the relationship between stability and amyloidosis.
    Hurshman Babbes AR, Powers ET, Kelly JW.
    Biochemistry; 2008 Jul 01; 47(26):6969-84. PubMed ID: 18537267
    [Abstract] [Full Text] [Related]

  • 8. Structural evidence for asymmetric ligand binding to transthyretin.
    Cianci M, Folli C, Zonta F, Florio P, Berni R, Zanotti G.
    Acta Crystallogr D Biol Crystallogr; 2015 Aug 01; 71(Pt 8):1582-92. PubMed ID: 26249340
    [Abstract] [Full Text] [Related]

  • 9. Anion shielding of electrostatic repulsions in transthyretin modulates stability and amyloidosis: insight into the chaotrope unfolding dichotomy.
    Hammarström P, Jiang X, Deechongkit S, Kelly JW.
    Biochemistry; 2001 Sep 25; 40(38):11453-9. PubMed ID: 11560493
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization.
    Green NS, Palaninathan SK, Sacchettini JC, Kelly JW.
    J Am Chem Soc; 2003 Nov 05; 125(44):13404-14. PubMed ID: 14583036
    [Abstract] [Full Text] [Related]

  • 11. Matrix metalloproteinase, hyaluronidase and elastase inhibitory potential of standardized extract of Centella asiatica.
    Nema NK, Maity N, Sarkar BK, Mukherjee PK.
    Pharm Biol; 2013 Sep 05; 51(9):1182-7. PubMed ID: 23763301
    [Abstract] [Full Text] [Related]

  • 12. The pathway by which the tetrameric protein transthyretin dissociates.
    Foss TR, Wiseman RL, Kelly JW.
    Biochemistry; 2005 Nov 29; 44(47):15525-33. PubMed ID: 16300401
    [Abstract] [Full Text] [Related]

  • 13. Orally administered diflunisal stabilizes transthyretin against dissociation required for amyloidogenesis.
    Sekijima Y, Dendle MA, Kelly JW.
    Amyloid; 2006 Dec 29; 13(4):236-49. PubMed ID: 17107884
    [Abstract] [Full Text] [Related]

  • 14. Pathogenesis of and therapeutic strategies to ameliorate the transthyretin amyloidoses.
    Sekijima Y, Kelly JW, Ikeda S.
    Curr Pharm Des; 2008 Dec 29; 14(30):3219-30. PubMed ID: 19075702
    [Abstract] [Full Text] [Related]

  • 15. R104H may suppress transthyretin amyloidogenesis by thermodynamic stabilization, but not by the kinetic mechanism characterizing T119 interallelic trans-suppression.
    Sekijima Y, Dendle MT, Wiseman RL, White JT, D'Haeze W, Kelly JW.
    Amyloid; 2006 Jun 29; 13(2):57-66. PubMed ID: 16911959
    [Abstract] [Full Text] [Related]

  • 16. Native state kinetic stabilization as a strategy to ameliorate protein misfolding diseases: a focus on the transthyretin amyloidoses.
    Johnson SM, Wiseman RL, Sekijima Y, Green NS, Adamski-Werner SL, Kelly JW.
    Acc Chem Res; 2005 Dec 29; 38(12):911-21. PubMed ID: 16359163
    [Abstract] [Full Text] [Related]

  • 17. Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.
    Connelly S, Mortenson DE, Choi S, Wilson IA, Powers ET, Kelly JW, Johnson SM.
    Bioorg Med Chem Lett; 2017 Aug 01; 27(15):3441-3449. PubMed ID: 28625364
    [Abstract] [Full Text] [Related]

  • 18. Review on the Structures and Activities of Transthyretin Amyloidogenesis Inhibitors.
    Guo X, Liu Z, Zheng Y, Li Y, Li L, Liu H, Chen Z, Wu L.
    Drug Des Devel Ther; 2020 Aug 01; 14():1057-1081. PubMed ID: 32210536
    [Abstract] [Full Text] [Related]

  • 19. [Studies on chemical constituents in herb of Centella asiatica].
    Yu QL, Gao WY, Zhang YW, Teng J, Duan HQ.
    Zhongguo Zhong Yao Za Zhi; 2007 Jun 01; 32(12):1182-4. PubMed ID: 17802882
    [Abstract] [Full Text] [Related]

  • 20. Pentacyclic triterpenoids from the medicinal herb, Centella asiatica (L.) Urban.
    James JT, Dubery IA.
    Molecules; 2009 Oct 09; 14(10):3922-41. PubMed ID: 19924039
    [Abstract] [Full Text] [Related]

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