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150 related items for PubMed ID: 3097260

  • 1. Primate-rodent 3H-MPTP binding differences, and biotransformation of MPTP to a reactive intermediate in vitro.
    Corsini GU, Pintus S, Bocchetta A, Piccardi MP, Del Zompo M.
    J Neural Transm Suppl; 1986; 22():55-60. PubMed ID: 3097260
    [Abstract] [Full Text] [Related]

  • 2. A reactive metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is formed in rat brain in vitro by type B monoamine oxidase.
    Corsini GU, Pintus S, Bocchetta A, Piccardi MP, Del Zompo M.
    J Pharmacol Exp Ther; 1986 Aug; 238(2):648-52. PubMed ID: 3488394
    [Abstract] [Full Text] [Related]

  • 3. Characterization of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) binding sites in C57BL/6 mouse brain: mutual effects of monoamine oxidase inhibitors and sigma ligands on MPTP and sigma binding sites.
    Itzhak Y, Mash D, Zhang SH, Stein I.
    Mol Pharmacol; 1991 Mar; 39(3):385-93. PubMed ID: 1848660
    [Abstract] [Full Text] [Related]

  • 4. The role of MAO in MPTP toxicity--a review.
    Glover V, Gibb C, Sandler M.
    J Neural Transm Suppl; 1986 Mar; 20():65-76. PubMed ID: 3091762
    [Abstract] [Full Text] [Related]

  • 5. Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. I. Evaluation of the biological activity of MPTP analogs.
    Youngster SK, Sonsalla PK, Sieber BA, Heikkila RE.
    J Pharmacol Exp Ther; 1989 Jun; 249(3):820-8. PubMed ID: 2786564
    [Abstract] [Full Text] [Related]

  • 6. Quantitative analysis of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolism in isolated rat hepatocytes.
    Di Monte D, Shinka T, Sandy MS, Castagnoli N, Smith MT.
    Drug Metab Dispos; 1988 Jun; 16(2):250-5. PubMed ID: 2898342
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of types A and B monoamine oxidase by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Fuller RW, Hemrick-Luecke SK.
    J Pharmacol Exp Ther; 1985 Mar; 232(3):696-701. PubMed ID: 3871853
    [Abstract] [Full Text] [Related]

  • 8. Selegiline and the prophylaxis of Parkinson's disease.
    Sandler M, Willoughby J, Glover V, Gibb C.
    J Neural Transm Suppl; 1987 Mar; 25():35-43. PubMed ID: 3123604
    [Abstract] [Full Text] [Related]

  • 9. Age-dependent effects of the 2'-methyl analog of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine: prevention by inhibitors of monoamine oxidase B.
    Finnegan KT, Irwin I, Delanney LE, Langston JW.
    J Pharmacol Exp Ther; 1995 May; 273(2):716-20. PubMed ID: 7752075
    [Abstract] [Full Text] [Related]

  • 10. Involvement of monoamine oxidase enzymes in the action of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine, a selective neurotoxin, in the squirrel monkey: binding and biochemical studies.
    Del Zompo M, Piccardi MP, Bernardi F, Bonuccelli U, Corsini GU.
    Brain Res; 1986 Jul 23; 378(2):320-4. PubMed ID: 3089539
    [Abstract] [Full Text] [Related]

  • 11. Development of fluorinated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs with potent nigrostriatal toxicity for potential use in positron emission tomography studies.
    Harik SI, Riachi NJ, Hritz MA, Berridge MS, Sayre LM.
    J Pharmacol Exp Ther; 1993 Aug 23; 266(2):790-5. PubMed ID: 8355208
    [Abstract] [Full Text] [Related]

  • 12. Biotransformation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in primary cultures of mouse astrocytes.
    Di Monte DA, Wu EY, Irwin I, Delanney LE, Langston JW.
    J Pharmacol Exp Ther; 1991 Aug 23; 258(2):594-600. PubMed ID: 1907660
    [Abstract] [Full Text] [Related]

  • 13. Importance of monoamine oxidase A in the bioactivation of neurotoxic analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Heikkila RE, Kindt MV, Sonsalla PK, Giovanni A, Youngster SK, McKeown KA, Singer TP.
    Proc Natl Acad Sci U S A; 1988 Aug 23; 85(16):6172-6. PubMed ID: 3137566
    [Abstract] [Full Text] [Related]

  • 14. Role for monoamine oxidase-A (MAO-A) in the bioactivation and nigrostriatal dopaminergic neurotoxicity of the MPTP analog, 2'Me-MPTP.
    Kindt MV, Youngster SK, Sonsalla PK, Duvoisin RC, Heikkila RE.
    Eur J Pharmacol; 1988 Feb 09; 146(2-3):313-8. PubMed ID: 3131149
    [Abstract] [Full Text] [Related]

  • 15. Species-dependent differences in monoamine oxidase A and B-catalyzed oxidation of various C4 substituted 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridinyl derivatives.
    Inoue H, Castagnoli K, Van Der Schyf C, Mabic S, Igarashi K, Castagnoli N.
    J Pharmacol Exp Ther; 1999 Nov 09; 291(2):856-64. PubMed ID: 10525109
    [Abstract] [Full Text] [Related]

  • 16. Enhanced hydroxyl radical generation by 2'-methyl analog of MPTP: suppression by clorgyline and deprenyl.
    Chiueh CC, Huang SJ, Murphy DL.
    Synapse; 1992 Aug 09; 11(4):346-8. PubMed ID: 1323883
    [Abstract] [Full Text] [Related]

  • 17. [3H]tryptamine binding sites are not identical to monoamine oxidase in rat brain.
    Perry DC, Grimm LJ, Kettler KG, Kellar KJ.
    J Neurochem; 1988 Nov 09; 51(5):1535-40. PubMed ID: 3139835
    [Abstract] [Full Text] [Related]

  • 18. D-deprenyl protects nigrostriatal neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity.
    Muralikrishnan D, Samantaray S, Mohanakumar KP.
    Synapse; 2003 Oct 09; 50(1):7-13. PubMed ID: 12872288
    [Abstract] [Full Text] [Related]

  • 19. Studies on the molecular mechanism of bioactivation of the selective nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Chiba K, Peterson LA, Castagnoli KP, Trevor AJ, Castagnoli N.
    Drug Metab Dispos; 1985 Oct 09; 13(3):342-7. PubMed ID: 2861994
    [Abstract] [Full Text] [Related]

  • 20. Deprenyl antagonizes acute lethality of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
    Fuller RW, Hemrick-Luecke SK, Perry KW.
    J Pharmacol Exp Ther; 1988 Nov 09; 247(2):531-5. PubMed ID: 3141609
    [Abstract] [Full Text] [Related]

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