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Journal Abstract Search

176 related items for PubMed ID: 30987252

  • 41.
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  • 42. Synthesis, In Silico and Kinetics Evaluation of N-(β-d-glucopyranosyl)-2-arylimidazole-4(5)-carboxamides and N-(β-d-glucopyranosyl)-4(5)-arylimidazole-2-carboxamides as Glycogen Phosphorylase Inhibitors.
    Homolya L, Mathomes RT, Varga L, Docsa T, Juhász L, Hayes JM, Somsák L.
    Int J Mol Sci; 2024 Apr 23; 25(9):. PubMed ID: 38731811
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  • 46. Synthesis of heterocyclic N-(β-D-glucopyranosyl)carboxamides for inhibition of glycogen phosphorylase.
    Kónya B, Docsa T, Gergely P, Somsák L.
    Carbohydr Res; 2012 Apr 01; 351():56-63. PubMed ID: 22365837
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  • 47. Halogen-substituted (C-β-D-glucopyranosyl)-hydroquinone regioisomers: synthesis, enzymatic evaluation and their binding to glycogen phosphorylase.
    Alexacou KM, Zhang YZ, Praly JP, Zographos SE, Chrysina ED, Oikonomakos NG, Leonidas DD.
    Bioorg Med Chem; 2011 Sep 01; 19(17):5125-36. PubMed ID: 21821421
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  • 48. Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes.
    Klabunde T, Wendt KU, Kadereit D, Brachvogel V, Burger HJ, Herling AW, Oikonomakos NG, Kosmopoulou MN, Schmoll D, Sarubbi E, von Roedern E, Schönafinger K, Defossa E.
    J Med Chem; 2005 Oct 06; 48(20):6178-93. PubMed ID: 16190745
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  • 49. Synthesis and pharmacological evaluation of bis-3-(3,4-dichlorophenyl)acrylamide derivatives as glycogen phosphorylase inhibitors.
    Onda K, Shiraki R, Yonetoku Y, Momose K, Katayama N, Orita M, Yamaguchi T, Ohta M, Tsukamoto S.
    Bioorg Med Chem; 2008 Sep 15; 16(18):8627-34. PubMed ID: 18723356
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  • 50. Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds.
    Watson KA, Mitchell EP, Johnson LN, Son JC, Bichard CJ, Orchard MG, Fleet GW, Oikonomakos NG, Leonidas DD, Kontou M.
    Biochemistry; 1994 May 17; 33(19):5745-58. PubMed ID: 8180201
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  • 51. The σ-hole phenomenon of halogen atoms forms the structural basis of the strong inhibitory potency of C5 halogen substituted glucopyranosyl nucleosides towards glycogen phosphorylase b.
    Kantsadi AL, Hayes JM, Manta S, Skamnaki VT, Kiritsis C, Psarra AM, Koutsogiannis Z, Dimopoulou A, Theofanous S, Nikoleousakos N, Zoumpoulakis P, Kontou M, Papadopoulos G, Zographos SE, Komiotis D, Leonidas DD.
    ChemMedChem; 2012 Apr 17; 7(4):722-32. PubMed ID: 22267166
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  • 52. Binding evaluation of fragment-based scaffolds for probing allosteric enzymes.
    Krimm I, Lancelin JM, Praly JP.
    J Med Chem; 2012 Feb 09; 55(3):1287-95. PubMed ID: 22229710
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  • 53. Ligand-based modelling followed by synthetic exploration unveil novel glycogen phosphorylase inhibitory leads.
    Habash M, Taha MO.
    Bioorg Med Chem; 2011 Aug 15; 19(16):4746-71. PubMed ID: 21788139
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  • 54. Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies.
    Oikonomakos NG, Kosmopoulou M, Zographos SE, Leonidas DD, Chrysina ED, Somsák L, Nagy V, Praly JP, Docsa T, Tóth B, Gergely P.
    Eur J Biochem; 2002 Mar 15; 269(6):1684-96. PubMed ID: 11895439
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  • 55. A new class of glycogen phosphorylase inhibitors.
    Lu Z, Bohn J, Bergeron R, Deng Q, Ellsworth KP, Geissler WM, Harris G, McCann PE, McKeever B, Myers RW, Saperstein R, Willoughby CA, Yao J, Chapman K.
    Bioorg Med Chem Lett; 2003 Nov 17; 13(22):4125-8. PubMed ID: 14592521
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  • 56. Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs.
    Oikonomakos NG, Kosmopoulou MN, Chrysina ED, Leonidas DD, Kostas ID, Wendt KU, Klabunde T, Defossa E.
    Protein Sci; 2005 Jul 17; 14(7):1760-71. PubMed ID: 15987904
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  • 57. Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
    Wen X, Sun H, Liu J, Cheng K, Zhang P, Zhang L, Hao J, Zhang L, Ni P, Zographos SE, Leonidas DD, Alexacou KM, Gimisis T, Hayes JM, Oikonomakos NG.
    J Med Chem; 2008 Jun 26; 51(12):3540-54. PubMed ID: 18517260
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  • 58. Glucose analogue inhibitors of glycogen phosphorylase: from crystallographic analysis to drug prediction using GRID force-field and GOLPE variable selection.
    Watson KA, Mitchell EP, Johnson LN, Cruciani G, Son JC, Bichard CJ, Fleet GW, Oikonomakos NG, Kontou M, Zographos SE.
    Acta Crystallogr D Biol Crystallogr; 1995 Jul 01; 51(Pt 4):458-72. PubMed ID: 15299833
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  • 59. Evaluation of designed ligands by a multiple screening method: application to glycogen phosphorylase inhibitors constructed with a variety of approaches.
    So SS, Karplus M.
    J Comput Aided Mol Des; 2001 Jul 01; 15(7):613-47. PubMed ID: 11688944
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  • 60. Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors.
    Chetter BA, Kyriakis E, Barr D, Karra AG, Katsidou E, Koulas SM, Skamnaki VT, Snape TJ, Psarra AG, Leonidas DD, Hayes JM.
    Bioorg Chem; 2020 Sep 01; 102():104003. PubMed ID: 32771768
    [Abstract] [Full Text] [Related]

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